Protective effect of thioredoxin upon NO-mediated cell injury in THP1 monocytic human cells

NITRIC OXIDE AND MACROPHAGE FUNCTION

1997 • 4,106 citations

Nitric oxide synthases: Roles, tolls, and controls

1994 • 2,945 citations

Establishment and characterization of a human histiocytic lymphoma cell line (U‐937)

1976 • 2,468 citations

Establishment and characterization of a human acute monocytic leukemia cell line (THP‐1)

1980 • 2,158 citations

Redox signaling: Nitrosylation and related target interactions of nitric oxide

1994 • 1,732 citations

NO at work

1994 • 1,493 citations

S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds.

1992 • 1,454 citations

H2O2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor.

1993 • 1,330 citations

Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide.

1985 • 1,146 citations

Thioredoxin catalyzes the reduction of insulin disulfides by dithiothreitol and dihydrolipoamide.

1979 • 907 citations

Nitric oxide synthase: Aspects concerning structure and catalysis

1994 • 865 citations

Distinct effects of thioredoxin and antioxidants onthe activation of transcription factors NF-kappa B and AP-1.

1994 • 694 citations

Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death.

1995 • 585 citations

Secretion of thioredoxin by normal and neoplastic cells through a leaderless secretory pathway.

1992 • 463 citations

Periplasmic superoxide dismutase protectsSalmonellafrom products of phagocyte NADPH-oxidase and nitric oxide synthase

1997 • 386 citations

Glutathione transferases catalyse the detoxication of oxidized metabolites (o-quinones) of catecholamines and may serve as an antioxidant system preventing degenerative cellular processes

1997 • 338 citations

Peroxynitrite-mediated DNA strand breakage activates poly-adenosine diphosphate ribosyl synthetase and causes cellular energy depletion in macrophages stimulated with bacterial lipopolysaccharide.

1996 • 322 citations

Cytokine-treated human neutrophils contain inducible nitric oxide synthase that produces nitration of ingested bacteria.

1996 • 310 citations

1,25-dihydroxyvitamin D3 inhibits proliferation of human promyelocytic leukaemia (HL60) cells and induces monocyte-macrophage differentiation in HL60 and normal human bone marrow cells

1983 • 307 citations

Thiol Compounds Interact with Nitric Oxide in Regulating Heme Oxygenase-1 Induction in Endothelial Cells

1997 • 297 citations

Amplification of calcium-induced gene transcription by nitric oxide in neuronal cells

1993 • 293 citations

The Comparative Toxicity of Nitric Oxide and Peroxynitrite to Escherichia coli

1995 • 286 citations

Nitric oxide is an important mediator for tumoricidal activity in vivo.

1994 • 249 citations

Thioredoxin, a gene found overexpressed in human cancer, inhibits apoptosis in vitro and in vivo.

1997 • 244 citations

Cloning and expression of a cDNA for human thioredoxin.

1988 • 239 citations

Induction of macrophage differentiation of human normal and leukemic myeloid stem cells by 1,25-dihydroxyvitamin D3 and its fluorinated analogues.

1984 • 236 citations

Induction of differentiation of the human histiocytic lymphoma cell line U-937 by 1 alpha,25-dihydroxycholecalciferol.

1983 • 215 citations

The effect of H2O2 upon thioredoxin-enriched lens epithelial cells.

1988 • 214 citations

Protective activity of adult T cell leukemia-derived factor (ADF) against tumor necrosis factor-dependent cytotoxicity on U937 cells.

1991 • 201 citations

Autocrine production of extracellular catalase prevents apoptosis of the human CEM T-cell line in serum-free medium.

1993 • 187 citations

Expression and regulation of myeloid-specific genes in normal and leukemic myeloid cells

1991 • 178 citations

Thioredoxin as a potent costimulus of cytokine expression.

1996 • 166 citations

IFN-gamma and 1,25(OH)2D3 induce on THP-1 cells distinct patterns of cell surface antigen expression, cytokine production, and responsiveness to contact with activated T cells.

1992 • 153 citations

The role of glutathione in lymphocyte activation. I. Comparison of inhibitory effects of buthionine sulfoximine and 2-cyclohexene-1-one by nuclear size transformation.

1985 • 153 citations

Vitamin D metabolites change the phenotype of monoblastic U937 cells.

1983 • 149 citations

Elevation of Manganese Superoxide Dismutase Gene Expression by Thioredoxin

1997 • 143 citations

Functional antagonism between vitamin D3 and retinoic acid in the regulation of CD14 and CD23 expression during monocytic differentiation of U-937 cells.

1993 • 127 citations

Adult T cell leukemia (ATL)-derived factor/human thioredoxin prevents apoptosis of lymphoid cells induced by L-cystine and glutathione depletion: possible involvement of thiol-mediated redox regulation in apoptosis caused by pro-oxidant state.

1997 • 126 citations

Regulation of CD14 expression during monocytic differentiation induced with 1 alpha,25-dihydroxyvitamin D3.

1994 • 112 citations

A Pro to His mutation in active site of thioredoxin increases its disulfide-isomerase activity 10-fold. New refolding systems for reduced or randomly oxidized ribonuclease.

1992 • 110 citations

Human vitamin D receptor phosphorylation by casein kinase II at Ser-208 potentiates transcriptional activation.

1996 • 108 citations

Glutathione modulates activation-dependent proliferation of human peripheral blood lymphocyte populations without regulating their activated function.

1991 • 101 citations

Redox Modulation of Iron Regulatory Proteins by Peroxynitrite

1997 • 83 citations

Role of Glutathione in Macrophage Activation: Effect of Cellular Glutathione Depletion on Nitrite Production and Leishmanicidal Activity

1995 • 74 citations

Involvement of Fcε:RII/CD23 and L-argininedependent pathway in IgE-mediated stimulation of human monocyte functions

1994 • 68 citations

Synergistic effect of retinoic acid and 1,25-dihydroxyvitamin D3 on the differentiation of the human monocytic cell line U937

1991 • 63 citations

Genomic cloning of human thioredoxin-encoding gene: mapping of the transcription start point and analysis of the promoter

1994 • 63 citations

A single exogenous stimulus activates resident rat macrophages for nitric oxide production and tumor cytotoxicity

1993 • 60 citations

Overexpression of CuZn superoxide dismutase protects RAW 264.7 macrophages against nitric oxide cytotoxicity

1999 • 49 citations

Vitamin D3-Binding Protein as a Precursor for Macrophage Activating Factor in the Inflammation-Primed Macrophage Activation Cascade in Rats

1996 • 40 citations

Role of nitric oxide in the anti-tumoral effect of retinoic acid and 1,25-dihydroxyvitamin D3 on human promonocytic leukemic cells

1996 • 37 citations

Mechanisms of differentiation of U937 leukemic cells induced by GM-CSF and 1,25(OH)2 vitamin D3

1991 • 34 citations

Regulation of interleukin-1 and tumour necrosis factor gene expression in myelomonocytic cell lines by 1,25-dihydroxyvitamin D3.

1991 • 32 citations

Vitamin D3- and retinoic acid-induced monocytic differentiation: interactions between the endogenous vitamin D3 receptor, retinoic acid receptors, and retinoid X receptors in U-937 cells.

1996 • 30 citations

IL-6 augments Fc IgE receptor (Fc epsilon RII/CD23) expression on human monoblastic/monocytic cell lines U937, THP-1, and Mono-Mac-6 but not on blood monocytes. Regulatory effects of IL-4 and IFN-gamma.

1991 • 28 citations