Changes in channel properties of acetylcholine receptors during the time course of thiol chemical modifications

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Down-Regulation of Na⁺/K⁺ATPase Activity by Human Parvovirus B19 Capsid Protein VP1

2013 • 8,607 citations

Regulation of the Voltage Gated K<sup>+</sup> Channel K<sub>v1.3</sub> by Recombinant Human Klotho Protein

2014 • 5,592 citations

Data transformations for improved display and fitting of single-channel dwell time histograms

1987 • 828 citations

Structural homology of Torpedo californica acetylcholine receptor subunits

1983 • 798 citations

Single acetylcholine-activated channels show burst-kinetics in presence of desensitizing concentrations of agonist

1980 • 608 citations

Nucleotide and deduced amino acid sequences of Torpedo californica acetylcholine receptor gamma subunit.

1983 • 412 citations

Identification of the alpha subunit half-cystine specifically labeled by an affinity reagent for the acetylcholine receptor binding site.

1984 • 408 citations

Location of functional regions of acetylcholine receptor α-subunit by site-directed mutagenesis

1985 • 390 citations

Acetylcholine receptor binding site contains a disulfide cross-link between adjacent half-cystinyl residues.

1986 • 361 citations

Activation of acetylcholine receptors on clonal mammalian BC3H‐1 cells by high concentrations of agonist.

1987 • 194 citations

Activation of Torpedo acetylcholine receptors expressed in mouse fibroblasts. Single channel current kinetics reveal distinct agonist binding affinities.

1990 • 193 citations

Functional consequences of agonist-mediated state transitions in the cholinergic receptor. Studies in cultured muscle cells.

1979 • 191 citations

Isolation of a clone coding for the alpha-subunit of a mouse acetylcholine receptor

1985 • 169 citations

Acetylcholine Receptor Structure, Function, and Evolution

1985 • 165 citations

Spontaneous openings of the acetylcholine receptor channel.

1984 • 162 citations

Acetylcholine receptor metabolism in a nonfusing muscle cell line.

1977 • 160 citations

Relationship between reversible antagonist occupancy and the functional capacity of the acetylcholine receptor.

1981 • 158 citations

Isolation and characterization of a cDNA clone for the complete protein coding region of the delta subunit of the mouse acetylcholine receptor.

1984 • 155 citations

The relationship between agonist occupation and the permeability response of the cholinergic receptor revealed by bound cobra alpha-toxin.

1980 • 140 citations

Activation of a nicotinic acetylcholine receptor

1984 • 132 citations

Activation of acetylcholine receptors on clonal mammalian BC3H‐1 cells by low concentrations of agonist.

1986 • 123 citations

Formation of the alpha-bungarotoxin binding site and assembly of the nicotinic acetylcholine receptor subunits occur in the endoplasmic reticulum.

1987 • 119 citations

Antibodies to synthetic peptides as probes for the binding site on the alpha subunit of the acetylcholine receptor.

1985 • 85 citations

Mechanisms of noncompetitive inhibition of acetylcholine-induced single-channel currents.

1989 • 66 citations

Purification of an acetylcholine receptor from a nonfusing muscle cell line

1977 • 65 citations

Effects of thio-group modifications on the ion permeability control and ligand binding properties of Torpedo californica acetylcholine receptor

1981 • 64 citations

Acetylcholine receptor: Modification of synaptic gating mechanism after treatment with a disulfide bond reducing agent

1975 • 61 citations

Isolation and sequence of cDNA clones coding for the precursor to the γ subunit of mouse muscle nicotinic acetylcholine receptor

1986 • 59 citations

Acetylcholine receptor enriched membranes: Acetylcholine binding and excitability after reduction in vitro

1977 • 59 citations

Effects of agonists and antagonists on the reactivity of the binding site disulfide in acetylcholine receptor from Torpedo californica

1980 • 50 citations

Independent activation of the acetylcholine receptor from Torpedo californica at two sites

1980 • 45 citations

A photoaffinity ligand of the acetylcholine‐binding site predominantly labels the region 179–207 of the α‐subunit on native acetylcholine receptor from Torpedo marmorata

1986 • 41 citations

Effects of thio-group modifications of Torpedo californica acetylcholine receptor on ion flux activation and inactivation kinetics

1984 • 41 citations

Relationships of agonist properties to the single channel kinetics of nicotinic acetylcholine receptors

1988 • 40 citations

Functional properties of human skeletal muscle acetylcholine receptors expressed by the TE671 cell line.

1988 • 40 citations

Modulation of acetylcholine receptor states by thiol modification

1980 • 37 citations

Nicotinic acetylcholine receptor: A structural model for α‐subunit peptide 188–201, the putative binding site for cholinergic agents

1988 • 36 citations

Assessment of the number of free cysteines and isolation and identification of cystine-containing peptides from acetylcholine receptor

1989 • 35 citations

Acetylcholine Noise: Analysis after Chemical Modification of Receptor

1974 • 34 citations

Acetylcholine receptor conformational transition on excitation masks disulphide bonds against reduction

1977 • 30 citations

The effects of reducing and alkylating agents on the acetylcholine receptor activity of frog sartorius muscle

1973 • 29 citations

Thiol-group modification of Torpedo californica acetylcholine receptor: subunit localization and effects on function

1986 • 19 citations

Effects of reduction and alkylation on ligand binding and cation transport by Torpedo californica acetylcholine receptor

1982 • 18 citations

Changes in neuromuscular junction endplate current time constants produced by sulfhydryl reagents.

1981 • 14 citations

Ligand-induced variations in the reactivity of thio groups of the .alpha.-subunit of the acetylcholine receptor from Torpedo californica

1984 • 11 citations

Effects of thiol modification and Ca++ on agonist-specific state transitions of nicotinic acetylcholine receptor from electroplax

1979 • 11 citations

Further kinetic analysis of the chemically modified acetylcholine receptor

1987 • 9 citations

The Classification of the Varietites of the Human Species 1

1885 • 3 citations