Frequent loss of heterozygosity on chromosomes Xp and 13q in human ovarian cancer

Mutations in the p53 gene occur in diverse human tumour types

1989 • 2,765 citations

Chromosome 17 Deletions and p53 Gene Mutations in Colorectal Carcinomas

1989 • 2,081 citations

p53: A Frequent Target for Genetic Abnormalities in Lung Cancer

1989 • 1,214 citations

A gene deleted in Kallmann's syndrome shares homology with neural cell adhesion and axonal path-finding molecules

1991 • 848 citations

Cancer statistics, 1990

1990 • 818 citations

Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines.

1990 • 607 citations

Familial breast-ovarian cancer locus on chromosome 17q12-q23

1991 • 513 citations

Loss of heterozygosity on chromosomes 3, 13, and 17 in small-cell carcinoma and on chromosome 3 in adenocarcinoma of the lung.

1987 • 487 citations

Reduction to Homozygosity of Genes on Chromosome 11 in Human Breast Neoplasia

1987 • 329 citations

LOSS OF CONSTITUTIONAL HETEROZYGOSITY IN HUMAN CANCER

1991 • 318 citations

ZFX has a gene structure similar to ZFY, the putative human sex determinant, and escapes X inactivation

1989 • 296 citations

Mechanisms of p53 loss in human sarcomas.

1990 • 273 citations

HUMAN TUMOR SUPPRESSOR GENES

1990 • 266 citations

Allelotype of human ovarian cancer.

1991 • 257 citations

Accumulation of genetic alterations and progression of primary breast cancer.

1991 • 229 citations

Loss of heterozygosity in human ductal breast tumors indicates a recessive mutation on chromosome 13.

1987 • 206 citations

Frequent allelic losses and mutations of the p53 gene in human ovarian cancer.

1991 • 194 citations

Frequent loss of heterozygosity on chromosomes 6q, 11, and 17 in human ovarian carcinomas.

1990 • 189 citations

Molecular analysis of genetic changes in the origin and development of renal cell carcinoma.

1991 • 181 citations

Deletions in human chromosome arms 11p and 13q in primary hepatocellular carcinomas

1988 • 161 citations

Allele loss from chromosome 17 in ovarian cancer.

1990 • 156 citations

Loss of heterozygosity on chromosomal segments 3p, 6q and 11p in human ovarian carcinomas.

1990 • 144 citations

Genetic Changes in Human Adrenocortical Carcinomas

1989 • 128 citations

Allele losses on chromosome 17 in human epithelial ovarian carcinoma.

1990 • 121 citations

Distinction of low grade from high grade human ovarian carcinomas on the basis of losses of heterozygosity on chromosomes 3, 6, and 11 and HER-2/neu gene amplification.

1991 • 108 citations

Epithelial Carcinoma of the Ovary: Current Strategies

1981 • 97 citations

Loss of somatic heterozygosity in hepatocellular carcinoma.

1991 • 77 citations

Loss of alleles at loci on chromosome 13 in human primary gastric cancers

1988 • 63 citations

Amplification and protein over-expression of the neu/HER-2/c-erbB-2 protooncogene in human breast carcinomas: relationship to loss of gene sequences on chromosome 17, family history and prognosis

1990 • 63 citations

Delayed Sexual Maturation Induced by Daily Melatonin Administration Eliminates the LH Response to Naloxone despite Normal Responsiveness to GnRH in Juvenile Male Rats

1988 • 62 citations

Allele Loss at the Retinoblastoma Locus in Human Ovarian Cancer

1991 • 61 citations

Allele loss at the c-Ha-ras1 locus in human ovarian cancer.

1989 • 51 citations

A dinucleotide repeat polymorphism at the DMD locus

1991 • 16 citations