Nestin-positive progenitor cells derived from adult human pancreatic islets of Langerhans contain side population (SP) cells defined by expression of the ABCG2 (BCRP1) ATP-binding cassette transporter

Global and societal implications of the diabetes epidemic

2001 • 5,825 citations

Islet Transplantation in Seven Patients with Type 1 Diabetes Mellitus Using a Glucocorticoid-Free Immunosuppressive Regimen

2000 • 5,125 citations

CNS stem cells express a new class of intermediate filament protein

1990 • 3,138 citations

Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo.

1996 • 2,901 citations

Purified hematopoietic stem cells can differentiate into hepatocytes in vivo

2000 • 2,366 citations

The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

2001 • 2,274 citations

Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells

2001 • 1,999 citations

Dystrophin expression in the mdx mouse restored by stem cell transplantation

1999 • 1,817 citations

From Marrow to Brain: Expression of Neuronal Phenotypes in Adult Mice

2000 • 1,709 citations

Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species

1997 • 1,116 citations

The Evolving Concept of a Stem Cell

2001 • 1,058 citations

Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells

1991 • 962 citations

Hematopoietic potential of stem cells isolated from murine skeletal muscle

1999 • 960 citations

Multipotential Nestin-Positive Stem Cells Isolated From Adult Pancreatic Islets Differentiate Ex Vivo Into Pancreatic Endocrine, Exocrine, and Hepatic Phenotypes

2001 • 788 citations

The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors

2002 • 754 citations

Independent regulatory elements in the nestin gene direct transgene expression to neural stem cells or muscle precursors

1994 • 583 citations

ABC Transporters as Phenotypic Markers and Functional Regulators of Stem Cells

2002 • 461 citations

The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoechst 33342 and is overexpressed in hematopoietic stem cells.

2002 • 398 citations

A Genetic Analysis of Neural Progenitor Differentiation

2001 • 241 citations

Bone marrow origin of hematopoietic progenitors and stem cells in murine muscle

2001 • 198 citations

Transduction of Murine Bone Marrow Cells With an MDR1 Vector Enables Ex Vivo Stem Cell Expansion, but These Expanded Grafts Cause a Myeloproliferative Syndrome in Transplanted Mice

1998 • 197 citations

Enforced P-glycoprotein pump function in murine bone marrow cells results in expansion of side population stem cells in vitro and repopulating cells in vivo

2000 • 169 citations

Hoechst dye efflux reveals a novel CD7+CD34− lymphoid progenitor in human umbilical cord blood

2000 • 128 citations

Identification of a candidate human neurohematopoietic stem-cell population

2001 • 117 citations

Hoechst dye efflux reveals a novel CD7+CD34− lymphoid progenitor in human umbilical cord blood

2000 • 116 citations

Somatic stem cell plasticity

2001 • 86 citations