Prolactin and the hyperphagia of lactation

Mammalian reproductive biology

1990 • 1,038 citations

Metabolic fuels and reproduction in female mammals

1992 • 677 citations

Minireview: From Anorexia to Obesity—The Yin and Yang of Body Weight Control

2003 • 385 citations

Focus on prolactin as a metabolic hormone

2006 • 313 citations

Anxiolytic and Anti-Stress Effects of Brain Prolactin: Improved Efficacy of Antisense Targeting of the Prolactin Receptor by Molecular Modeling

2001 • 259 citations

The effect of pregnancy and lactation on food intake, gastrointestinal anatomy and the absorptive capacity of the small intestine in the albino rat

1975 • 255 citations

A Receptor-Mediated Mechanism for the Transport of Prolactin from Blood to Cerebrospinal Fluid*

1987 • 247 citations

Targeted Deletion of the PRL Receptor: Effects on Islet Development, Insulin Production, and Glucose Tolerance

2002 • 241 citations

Increased hypothalamic expression of prolactin in lactation: involvement in behavioural and neuroendocrine stress responses

2002 • 212 citations

Induction of Neuropeptide Y Gene Expression in the Dorsal Medial Hypothalamic Nucleus in Two Models of theAgoutiObesity Syndrome

1997 • 207 citations

Atlas of the neurons that express mRNA for the long form of the prolactin receptor in the forebrain of the female rat

1997 • 183 citations

Atlas of the neurons that express mRNA for the long form of the prolactin receptor in the forebrain of the female rat

1997 • 178 citations

Lactation alters neuropeptide-Y and proopiomelanocortin gene expression in the arcuate nucleus of the rat.

1993 • 174 citations

Inhibition of Gonadotropin Secretion During Lactation in the Rat: Relative Contribution of Suckling and Ovarian Steroids1

1977 • 157 citations

The Brain Prolactin System: Involvement in Stress Response Adaptations in Lactation

2002 • 154 citations

Body Weight and Fat Deposition in Prolactin Receptor-Deficient Mice**This work was supported in part by grants from the NICHD (HD-24192 to M.F.), the Juvenile Diabetes Foundation (196029 to M.F.), Eli Lilly & Co. (to M.F.), and INSERM (to P.A.K.).

2001 • 146 citations

Region-Specific Reduction in Leptin-Induced Phosphorylation of Signal Transducer and Activator of Transcription-3 (STAT3) in the Rat Hypothalamus Is Associated with Leptin Resistance during Pregnancy

2004 • 141 citations

Induction of neuropeptide Y expression in dorsomedial hypothalamus of diet-induced obese mice

1998 • 140 citations

Prolactin Receptor Gene Expression in Rat Mammary Gland and Liver during Pregnancy and Lactation

1991 • 140 citations

Altered Expression of Agouti-Related Protein and Its Colocalization with Neuropeptide Y in the Arcuate Nucleus of the Hypothalamus during Lactation*

1999 • 138 citations

Anorectic effects of estrogen may be mediated by decreased neuropeptide-Y release in the hypothalamic paraventricular nucleus.

1994 • 136 citations

NUTRITIONAL REQUIREMENTS OF PREGNANT AND LACTATING RATS STUDIED BY THE SELFSELECTION METHOD

1938 • 131 citations

The utilization of protein and energy during lactation in the rat, with particular regard to the use of fat accumulated in pregnancy

1982 • 128 citations

The prolactin/growth hormone receptor family: structure/function relationships.

1997 • 127 citations

The Acute Suckling Stimulus Induces Expression of Neuropeptide Y (NPY) in Cells in the Dorsomedial Hypothalamus and Increases NPY Expression in the Arcuate Nucleus*

1998 • 119 citations

Prolactin stimulates food intake in a dose-dependent manner

1989 • 118 citations

Weaning in rats: II. Pup behavior patterns

1990 • 116 citations

Changes in bone mineral and bone formation rates during pregnancy and lactation in rats

1986 • 115 citations

Suppression of Leptin Receptor Messenger Ribonucleic Acid and Leptin Responsiveness in the Ventromedial Nucleus of the Hypothalamus during Pregnancy in the Rat

2005 • 110 citations

Food intake, body weight, and adiposity in female rats: actions and interactions of progestins and antiestrogens

1981 • 110 citations

Participation of prolactin receptors and phosphatidylinositol 3-kinase and MAP kinase pathways in the increase in pancreatic islet mass and sensitivity to glucose during pregnancy

2004 • 108 citations

Expression of the long form of the prolactin receptor in magnocellular oxytocin neurons is associated with specific prolactin regulation of oxytocin neurons

2006 • 101 citations

Effects of systemic and central prolactin injections on food intake, weight gain, and estrous cyclicity in female rats

1993 • 98 citations

The Suppression of Pulsatile Luteinizing Hormone Secretion during Lactation in the Rat*

1984 • 97 citations

In vivo release and gene upregulation of brain prolactin in response to physiological stimuli

2004 • 94 citations

Hyperprolactinemia stimulates food intake in the female rat

1986 • 93 citations

Neuropeptide Y (NPY) neurons in the arcuate nucleus (ARH) and dorsomedial nucleus (DMH), areas activated during lactation, project to the paraventricular nucleus of the hypothalamus (PVH)

1998 • 91 citations

Control of food intake in the lactating rat: Role of suckling and hormones

1976 • 89 citations

Quantitation of prolactin receptor mRNA in the maternal rat brain during pregnancy and lactation

2003 • 87 citations

Detection of prolactin receptor (PRL-R) mRNA in the rat hypothalamus and pituitary gland.

1992 • 86 citations

Lactation Suppresses Diurnal Rhythm of Serum Leptin

1998 • 86 citations

Increased expression of both short and long forms of prolactin receptor mRNA in hypothalamic nuclei of lactating rats

1999 • 85 citations

Neuroanatomical specificity of prolactin-induced hyperphagia in virgin female rats

2000 • 84 citations

Neuropeptide Y and Tuberoinfundibular Dopamine Activities Are Altered during Lactation: Role of Prolactin**This work was supported by NIH Grants HD-14643 and HD-18185 and Oregon Regional Primate Research Center Grant RR-00163.

1999 • 81 citations

Expression of mRNA for Prolactin Receptor (Long Form) in Dopamine and Pro‐Opiomelanocortin Neurones in the Arcuate Nucleus of Non‐Pregnant and Lactating Rats

2005 • 79 citations

BODY WEIGHT AND FOOD CONSUMPTION OF LACTATING RATS NURSING VARIOUS SIZES OF LITTERS

1967 • 78 citations

Changes in Leptin Levels during Lactation: Implications for Lactational Hyperphagia and Anovulation

2000 • 78 citations

Inhibition of Uncoupling Protein Expression during Lactation: Role of Leptin

2003 • 76 citations

Meal patterning in the lactating rat

1980 • 76 citations

The effect of central administration of prolactin on food intake in virgin female rats is dose-dependent, occurs in the absence of ovarian hormones and the latency to onset varies with feeding regimen

1996 • 75 citations

Hypoadiponectinemia in Lean Lactating Women: Prolactin Inhibits Adiponectin Secretion from Human Adipocytes

2006 • 72 citations

Melanocortin 4 Receptor-Mediated Hyperphagia and Activation of Neuropeptide Y Expression in the Dorsomedial Hypothalamus during Lactation

2004 • 70 citations

Changes in the pulsatile secretion of LH after the removal of and subsequent resuckling by pups in ovariectomized lactating rats

1989 • 66 citations

Regulation of Hypothalamic Neuropeptide Y Messenger Ribonucleic Acid Expression during Lactation: Role of Prolactin

2003 • 65 citations

BODY WEIGHT AND FOOD CONSUMPTION OF LACTATING RATS: EFFECTS OF OVARIECTOMY AND OF ARREST AND RESUMPTION OF SUCKLING

1967 • 64 citations

Prolactin and growth hormone stimulate food intake in ring doves

1988 • 61 citations

Vitamin D-dependent calcium-binding protein. Changes during gestation, prenatal and postnatal development in rats.

1979 • 61 citations

The role of lactogenic hormones in maternal behavior in female rats

1994 • 61 citations

Prolactin induction of insulin gene expression: the roles of glucose and glucose transporter-2

2000 • 60 citations

Induction of Neuropeptide Y Gene Expression in the Dorsal Medial Hypothalamic Nucleus in Two Models of the Agouti Obesity Syndrome

1997 • 60 citations

THE INFLUENCE OF SUCKLING ON FOOD INTAKE AND GROWTH OF ADULT FEMALE RATS

1954 • 57 citations

Thermogenesis and the energetics of pregnancy and lactation

1989 • 56 citations

Mechanisms of Suppression of Ovarian Follicular Development During Lactation in the Rat

1982 • 55 citations

Altered Expression of Agouti-Related Protein and Its Colocalization with Neuropeptide Y in the Arcuate Nucleus of the Hypothalamus during Lactation

1999 • 53 citations

Differential proopiomelanocortin gene expression in the medial basal hypothalamus of rats during pregnancy and lactation

1997 • 53 citations

Nuclear translocation of STAT5 and increased expression of Fos related antigens (FRAs) in hypothalamic dopaminergic neurons after prolactin administration

2001 • 52 citations

Peripheral blood and ovarian levels of sex steroids in the lactating rat.

1982 • 50 citations

Lactation alters neuropeptide-Y and proopiomelanocortin gene expression in the arcuate nucleus of the rat

1993 • 50 citations

Anorectic effects of estrogen may be mediated by decreased neuropeptide- Y release in the hypothalamic paraventricular nucleus

1994 • 47 citations

Detection of prolactin receptor (PRL-R) mRNA in the rat hypothalamus and pituitary gland

1992 • 46 citations

Mechanism of the neuroleptic-induced obesity in female rats

1998 • 46 citations

Targeted Deletion of the PRL Receptor: Effects on Islet Development, Insulin Production, and Glucose Tolerance

2002 • 46 citations

Mechanisms regulating hormone release and the duration of dioestrus in the lactating rat

1983 • 44 citations

Functional mapping of neural sites mediating prolactin-induced hyperphagia in doves

1993 • 44 citations

Role of the Ventromedial Hypothalamus in Prolactin-Induced Hyperphagia in Ring Doves

1999 • 44 citations

Effects of Suckling on Pituitary Release of Prolactin, GH, and TSH in Postpartum Lactating Rats

1969 • 43 citations

Neuropeptide Y and Tuberoinfundibular Dopamine Activities Are Altered during Lactation: Role of Prolactin

1999 • 36 citations

Prolactin potentiates insulin-stimulated leptin expression and release from differentiated brown adipocytes

2004 • 35 citations

Effect of suckling upon the secretion and release of prolactin from the pituitary of the lactating rat.

1971 • 34 citations

Metabolic Adaptations in Skeletal Muscle during Lactation: Complementary Deoxyribonucleic Acid Microarray and Real-Time Polymerase Chain Reaction Analysis of Gene Expression

2004 • 31 citations

The Acute Suckling Stimulus Induces Expression of Neuropeptide Y (NPY) in Cells in the Dorsomedial Hypothalamus and Increases NPY Expression in the Arcuate Nucleus

1998 • 31 citations

Prolactin stimulates food intake in the absence of ovarian progesterone

1989 • 31 citations

SUPPRESSION OF PROGESTERONE SECRETION IN LACTATING RATS BY ADMINISTRATION OF ERGOCORNINE AND THE EFFECT OF PROLACTIN REPLACEMENT

1975 • 30 citations

Neuroendocrine regulation of salt and water metabolism

1997 • 30 citations

Time course and response specificity of prolactin-induced hyperphagia in ring doves

1989 • 30 citations

Suppression of LH secretion in food-restricted lactating females: effects of ovariectomy and bromocryptine treatment

1995 • 29 citations

Body Weight and Fat Deposition in Prolactin Receptor-Deficient Mice

2001 • 27 citations

Diurnal changes in hypothalamic neuropeptide and SOCS-3 expression: effects of lactation and relationship with serum leptin and food intake

2004 • 27 citations

Elevated calcium, phosphorus, and magnesium retention in pregnant rats prior to the onset of fetal skeletal mineralization

1988 • 24 citations

Brown adipose tissue thermogenesis and the energetics of lactation in rodents.

1985 • 22 citations

Prolactin, prolactin receptor and uncoupling proteins during fetal and neonatal development

2003 • 22 citations

The Contribution of Changes in Milk Delivery to the Prolongation of Lactational Infertility Induced by Food Restriction or Increased Litter Size

1998 • 21 citations

Site of Action of Prolactin in the Suppression of Gonadotropin Secretion During Lactation in the Rat: Effect on Pituitary Responsiveness to LHRH1

1981 • 19 citations

Prolactin levels in juvenile and adult rats following acute restraint and the open field

2000 • 17 citations

Decrease in litter weight gain and in progesterone secretion in lactating rats treated with antiserum to rat prolactin

1976 • 16 citations

Factors influencing the self-selection of calcium in lactating rats

1989 • 15 citations

Short-term in vivo regulation of prolactin receptors in the liver, testes, kidneys, and mammary gland of rats.

1992 • 9 citations

EFFECT OF PERPHENAZINE DURING LATE PREGNANCY ON PROLACTIN PRODUCTION AND LACTOGENESIS IN THE RAT

1973 • 6 citations

Effects of cyclic steroid hormone replacement on prolactin and luteinizing hormone surges in female rats

2004 • 5 citations