Changes in motoric, exploratory and emotional behaviours and neuronal acetylcholine content and 5‐HT turnover in histidine decarboxylase‐KO mice
Data up to Jan 2025
Total Citations Per Year
Abstract
References (50)
Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype?
1996 • 895 citations
The role of histamine and the tuberomamillary nucleus in the nervous system
2003 • 890 citations
The Mesolimbic Dopamine System: From Motivation to Action
1992 • 591 citations
Anatomical, Physiological, and Pharmacological Characteristics of Histidine Decarboxylase Knock-Out Mice: Evidence for the Role of Brain Histamine in Behavioral and Sleep–Wake Control
2002 • 472 citations
Locomotor Activity in D2 Dopamine Receptor-Deficient Mice Is Determined by Gene Dosage, Genetic Background, and Developmental Adaptations
1998 • 448 citations
Cortical cholinergic inputs mediating arousal, attentional processing and dreaming: differential afferent regulation of the basal forebrain by telencephalic and brainstem afferents
1999 • 418 citations
Mice lacking histidine decarboxylase exhibit abnormal mast cells
2001 • 393 citations
A critical role of the posterior hypothalamus in the mechanisms of wakefulness determined by microinjection of muscimol in freely moving cats
1989 • 317 citations
PHYSIOLOGICAL REVIEW ARTICLE: Brain structures and mechanisms involved in the control of cortical activation and wakefulness, with emphasis on the posterior hypothalamus and histaminergic neurons
2000 • 242 citations
Behavioral Characterization of Mice Lacking Histamine H3 Receptors
2002 • 220 citations
Comparison of human, mouse, rat, and guinea pig histamine H4 receptors reveals substantial pharmacological species variation.
2001 • 203 citations
Hippocampal acetylcholine and habituation learning
1998 • 200 citations
Ethopharmacological analysis of the effects of putative ‘anxiogenic’ agents in the mouse elevated plus-maze
1995 • 159 citations
Cholinergic nucleus basalis neurons are excited by histamine in vitro
1995 • 130 citations
Effects of conditioned fear stress on serotonin neurotransmission and freezing behavior in rats
1999 • 129 citations
Pharmacology of α fluoromethylhistidine, a specific inhibitor of histidine decarboxylase
1990 • 114 citations
Histamine-induced arousal in the conscious and pentobarbital-pretreated rat.
1982 • 107 citations
Two Novel and Selective Nonimidazole H3 Receptor Antagonists A-304121 and A-317920: II. In Vivo Behavioral and Neurophysiological Characterization
2003 • 105 citations
Anxiety and cognition in histamine H3 receptor−/− mice
2004 • 99 citations
Molecular Modeling and Site-Specific Mutagenesis of the Histamine-Binding Site of the Histamine H4Receptor
2002 • 99 citations
Superior Water Maze Performance and Increase in Fear-Related Behavior in the Endothelial Nitric Oxide Synthase-Deficient Mouse Together with Monoamine Changes in Cerebellum and Ventral Striatum
2000 • 97 citations
Thioperamide, the selective histamine H3 receptor antagonist, attenuates stimulant-induced locomotor activity in the mouse
1994 • 93 citations
Histidine-Decarboxylase Knockout Mice Show Deficient Nonreinforced Episodic Object Memory, Improved Negatively Reinforced Water-Maze Performance, and Increased Neo- and Ventro-Striatal Dopamine Turnover
2003 • 92 citations
Increased methamphetamine‐induced locomotor activity and behavioral sensitization in histamine‐deficient mice
2002 • 85 citations
The behavioral and biochemical effects of thioperamide, a histamine H3-receptor antagonist, in a light/dark test measuring anxiety in mice
1993 • 67 citations
Effects of histamine H 3 receptor ligands in experimental models of anxiety and depression
1999 • 67 citations
Histamine and spontaneous motor activity: Biphasic changes, receptors involved and participation of the striatal dopamine system
1998 • 65 citations
Mouse light/dark box test reveals anxiogenic-like effects by activation of histamine H1 receptors
2002 • 64 citations
Chemical kindling induced by pentylenetetrazol in histamine H1 receptor gene knockout mice (H1KO), histidine decarboxylase-deficient mice (HDC−/−) and mast cell-deficient W/Wv mice
2003 • 61 citations
Facilitation of learning after lesions of the tuberomammillary nucleus region in adult and aged rats
1998 • 61 citations
The role of brain histamine in acute and chronic stresses
2000 • 61 citations
Effects of thioperamide, a histamine H3 receptor antagonist, on locomotor activity and brain histamine content in mast cell-deficient mice
1991 • 60 citations
Intranasal Administration of the Dopaminergic Agonists <scp>l</scp>‐DOPA, Amphetamine, and Cocaine Increases Dopamine Activity in the Neostriatum: A Microdialysis Study in the Rat
1997 • 58 citations
Anxiolytic-like behavior after lesion of the tuberomammillary nucleus E2-region
1998 • 58 citations
Intraventricular infusion of the histamine H 1 receptor antagonist chlorpheniramine improves maze performance and has anxiolytic-like effects in aged hybrid Fischer 344×Brown Norway rats
1999 • 52 citations
Targeting disruption of histamine H1 receptors in mice: Behavioral and neurochemical characterization
1998 • 46 citations
Pharmacology of sensory stimulation-evoked increases in frontal cortical acetylcholine release
1998 • 46 citations
Histamine in dorsal and ventral hippocampus. II. Effects of H1 and H2 histamine antagonists on exploratory behavior in male rats
1986 • 44 citations
The effect of neuroleptics on acetylcholine concentration and choline uptake in striatum: Implications for regulation of acetylcholine metabolism.
1978 • 41 citations
Effects of drugs acting as histamine releasers or histamine receptor blockers on an experimental anxiety model in mice
2000 • 40 citations
Effects of alpha-fluoromethylhistidine on locomotor activity, brain histamine and catecholamine contents in rats.
1992 • 40 citations
The Anxiolytic-Like Properties of Two Selective MAOIs, Moclobemide and Selegiline, in a Standard and an Enhanced Light/Dark Aversion Test
2000 • 36 citations
Differential modulation of frontal cortex acetylcholine by injection of substance P into the nucleus basalis magnocellularis region in the freely-moving vs. the anesthetized preparation
2000 • 36 citations
The graded anxiety test: a novel test of murine unconditioned anxiety based on the principles of the elevated plus-maze and light–dark test
2002 • 26 citations
Long-term depletion of brain histamine induced by α-fluoromethylhistidine increases feeding-associated locomotor activity in mice with a modulation of brain amino acid levels
1995 • 25 citations
Effects of thioperamide on locomotor activity and on memory processes
1998 • 20 citations
Histaminergic facilitation of electrocorticographic activation: role of basal forebrain, thalamus, and neocortex
2003 • 18 citations
Memory Improvement by Post-trial Injection of Lidocaine into the Tuberomammillary Nucleus, the Source of Neuronal Histamine
1999 • 15 citations
Recovery from fatigue: changes in local brain 2-[18F]fluoro-2-deoxy-d-glucose utilization measured by autoradiography and in brain monoamine levels of rat
2003 • 14 citations
Haloperidol-induced decrease in striatal acetylcholine content in rats killed by either decapitation or microwave radiation
1976 • 8 citations