Intraventricular infusion of the histamine H 1 receptor antagonist chlorpheniramine improves maze performance and has anxiolytic-like effects in aged hybrid Fischer 344×Brown Norway rats

Developments of a water-maze procedure for studying spatial learning in the rat

1984 • 6,896 citations

The rat brain in stereotaxic coordinates (2nd edn)

1987 • 1,743 citations

Tests for emotionality in rats and mice: A review

1973 • 1,561 citations

Histaminergic transmission in the mammalian brain

1991 • 948 citations

High-Frequency Oscillations in the Output Networks of the Hippocampal–Entorhinal Axis of the Freely Behaving Rat

1996 • 575 citations

Behavioural profiles of two Wistar rat lines selectively bred for high or low anxiety-related behaviour

1998 • 323 citations

Diversity of neuronal nicotinic acetylcholine receptors: Lessons from behavior and implications for cns therapeutics

1995 • 258 citations

Neuropharmacology of the histaminergic neuron system in the brain and its relationship with behavioral disorders

1994 • 245 citations

Neuronal histamine deficit in Alzheimer's disease

1997 • 166 citations

The tuberomammillary nucleus projections in the control of learning, memory and reinforcement processes: evidence for an inhibitory role

1997 • 134 citations

Behavioral differences between outbred Wistar, inbred Fischer 344, Brown Norway, and hybrid Fischer 344 × Brown Norway rats

1996 • 101 citations

Behavioral assessment of aging in male Fischer 344 and Brown Norway rat strains and their F1 hybrid

1994 • 88 citations

Brain histamine in Alzheimer's disease.

1989 • 80 citations

The H1- and H2-histamine blockers chlorpheniramine and ranitidine applied to the nucleus basalis magnocellularis region modulate anxiety and reinforcement related processes

1998 • 79 citations

Selecting Animal Models of Human Aging: Inbred Strains Often Exhibit Less Biological Uniformity Than F1 Hybrids

1994 • 79 citations

Nonparametric analysis of response curves

1980 • 75 citations

The behavioral and biochemical effects of thioperamide, a histamine H3-receptor antagonist, in a light/dark test measuring anxiety in mice

1993 • 67 citations

Facilitation of learning after lesions of the tuberomammillary nucleus region in adult and aged rats

1998 • 61 citations

Anxiolytic-like behavior after lesion of the tuberomammillary nucleus E2-region

1998 • 58 citations

Diazepam-induced decrease in histamine turnover in mouse brain

1986 • 54 citations

Inhibition of histamine turnover by 8-OH-DPAT, buspirone and 5-hydroxytryptophan in the mouse and rat brain

1992 • 46 citations

Endogenous benzodiazepine modulation of memory processes

1990 • 42 citations

Reciprocal changes in expression of mRNA for nerve growth factor and its receptors TrkA and LNGFR in brain of aged rats in relation to maze learning deficits

1997 • 40 citations

Histamine H₁ Receptor Antagonists Produce Increases in Extracellular Acetylcholine in Rat Frontal Cortex and Hippocampus

1998 • 36 citations

Elevated levels of histamine metabolites in cerebrospinal fluid of aging, healthy humans.

1988 • 34 citations

Chronic administration of neurokinin SP improves maze performance in aged Rattus norvegicus

1994 • 34 citations

The histamine H1-antagonist chlorpheniramine facilitates learning in aged rats

1997 • 31 citations

Plasticity in crossed and uncrossed tuberomammillary-striatal projections in relation to recovery from behavioral asymmetries induced by hemivibrissotomy

1990 • 29 citations

Hippocampal histamine receptors and conflictive exploration in the rat: studies using the elevated asymmetric plus-maze

1997 • 29 citations

Delayed acquisition of eyeblink conditioning in aged F1 hybrid (Fischer-344 × brown Norway) rats

1992 • 28 citations

Measurement of histamine metabolites in brain and cerebrospinal fluid provides insights into histaminergic activity

1994 • 28 citations

Age-related changes in brain histamine

1984 • 27 citations

Differential modulation of hippocampal signal transfer by tuberomammillary nucleus stimulation in freely moving rats dependent on behavioral state

1998 • 24 citations

Absence of amnestic effect of an anxiolytic 5-HT3 antagonist (BRL 46470A) injected into basolateral amygdala, as opposed to diazepam

1993 • 13 citations

Summary and recommendations of the Venice conference on animal models for aging research

1991 • 11 citations

The influence of α-fluoromethylhistidine on the regional brain histamine and plasma corticosterone levels in aging

1987 • 9 citations

Neurochemical studies on central histaminergic neuron system of senescence accelerated mice

1992 • 8 citations

Relationship between Behavioral Recovery from Unilateral 6-OHDA Lesion of the Substania Nigra and Changes in the Tuberomammillary-Striatal Projection as Measured by HRP-Labelling

1998 • 5 citations