Nociceptin receptor-mediated Ca2+ channel inhibition and its desensitization in NG108-15 cells

Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor

1995 • 1,887 citations

Orphanin FQ: A Neuropeptide That Activates an Opioidlike G Protein-Coupled Receptor

1995 • 1,800 citations

Cloning of a Delta Opioid Receptor by Functional Expression

1992 • 1,225 citations

ORL1, a novel member of the opioid receptor family

1994 • 1,060 citations

Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a μ, δ or κ opioid receptor type

1994 • 593 citations

cDNA cloning and regional distribution of a novel member of the opioid receptor family

1994 • 404 citations

Increase by the ORL₁ receptor (opioid receptor‐like₁) ligand, nociceptin, of inwardly rectifying K conductance in dorsal raphe nucleus neurones

1996 • 231 citations

Bidirectional modulatory effect of orphanin FQ on morphine‐induced analgesia: antagonism in brain and potentiation in spinal cord of the rat

1997 • 230 citations

Nociceptin receptor coupling to a potassium conductance in rat locus coeruleus neurones in vitro

1996 • 223 citations

The effect of nociceptin on Ca²⁺ channel current and intracellular Ca²⁺ in the SH‐SY5Y human neuroblastoma cell line

1996 • 208 citations

Facilitation of Ca2+ current in excitable cells

1996 • 190 citations

Modulation of Voltage-Gated Calcium Channels by Orphanin FQ in Freshly Dissociated Hippocampal Neurons

1996 • 181 citations

Intracerebroventricular orphanin FQ/Nociceptin supresses dopamine release in the nucleus accumbens of anaesthetized rats

1996 • 171 citations

Actions of the ORL1 receptor ligand nociceptin on membrane properties of rat periaqueductal gray neurons in vitro.

1997 • 170 citations

Actions of the ORL₁Receptor Ligand Nociceptin on Membrane Properties of Rat Periaqueductal Gray NeuronsIn Vitro

1997 • 151 citations

Transmitter-mediated inhibition of N-type calcium channels in sensory neurons involves multiple GTP-binding proteins and subunits

1995 • 136 citations

Inhibition by nociceptin of neurogenic inflammation and the release of SP and CGRP from sensory nerve terminals

1997 • 134 citations

Inhibitory action of nociceptin on spinal dorsal horn neurones of the rat, in vivo

1996 • 133 citations

Nociceptin induced inhibition of K⁺ evoked glutamate release from rat cerebrocortical slices

1996 • 128 citations

Inhibition of tachykinin release from peripheral endings of sensory nerves by nociceptin, a novel opioid peptide

1996 • 122 citations

Modulation of excitatory synaptic transmission by nociceptin in superficial dorsal horn neurones of the neonatal rat spinal cord

1997 • 119 citations

Nociceptin/Orphanin FQ Metabolism: Role of Aminopeptidase and Endopeptidase 24.15

1997 • 113 citations

Theoretical effects of single and multiple transducer receptor coupling proteins on estimates of the relative potency of agonists.

1989 • 113 citations

Depression of glutamatergic transmission by nociceptin in the neonatal rat hemisected spinal cord preparation in vitro

1996 • 104 citations

Nociceptin (orphanin FQ), an endogenous ligand for the QRL1 (opioid-receptor-like1) receptor; modulates responses of trigeminal neurons evoked by excitatory amino acids and somatosensory stimuli

1996 • 62 citations

Functional expression, activation and desensitization of opioid receptor‐like receptor ORL₁ in neuroblastoma×glioma NG108‐15 hybrid cells

1997 • 62 citations

Activation of mitogen‐activated protein kinase by the nociceptin receptor expressed in Chinese hamster ovary cells

1997 • 43 citations

Coupling of the Cloned μ‐Opioid Receptor with the ω‐Conotoxin‐Sensitive Ca²⁺ Current in NG108‐15 Cells

1995 • 26 citations

Desensitization and resensitization of δ‐opioid receptor‐mediated Ca²⁺ channel inhibition in NG108‐15 cells

1998 • 24 citations