A ribonuclease inhibitor expresses anti-angiogenic properties and leads to reduced tumor growth in mice.

Angiogenic Factors

1987 • 3,702 citations

Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth

1990 • 1,308 citations

Polymers for the sustained release of proteins and other macromolecules

1976 • 1,127 citations

Tumor Angiogenesis

1985 • 1,038 citations

Isolation and characterization of angiogenin, an angiogenic protein from human carcinoma cells

1985 • 911 citations

Amino acid sequence of human tumor derived angiogenin

1985 • 357 citations

Lymphocyte-induced angiogenesis: a quantitative and sensitive assay of the graft-vs.-host reaction.

1975 • 285 citations

Cloning and sequencing of the intronless gene for angiogenin, a human angiogenesis factor

1985 • 273 citations

Vascular attack as a therapeutic strategy for cancer

1990 • 267 citations

Tumor-related angiogenesis

1989 • 256 citations

Inhibition of angiogenesis and tumor growth in the brain. Suppression of endothelial cell turnover by penicillamine and the depletion of copper, an angiogenic cofactor.

1990 • 230 citations

Site-directed mutagenesis of histidine-13 and histidine-114 of human angiogenin. Alanine derivatives inhibit angiogenin-induced angiogenesis

1989 • 191 citations

Human placental ribonuclease inhibitor abolishes both angiogenic and ribonucleolytic activities of angiogenin.

1987 • 189 citations

Angiogenesis in the Mouse Cornea

1979 • 188 citations

Isolation of angiogenin from normal human plasma

1987 • 187 citations

Tumor-induced neovascularization in the mouse eye.

1982 • 161 citations

Inhibition of angiogenesis and tumor growth by a synthetic laminin peptide, CDPGYIGSR-NH2.

1991 • 157 citations

Control of tumor growth in animals by infusion of an angiogenesis inhibitor.

1980 • 154 citations

Heterogeneity of mouse vascular endothelium. In vitro studies of lymphatic, large blood vessel and microvascular endothelial cells.

1987 • 143 citations

Specific binding of angiogenin to calf pulmonary artery endothelial cells.

1989 • 134 citations

A hemangioendothelioma-derived cell line: its use as a model for the study of endothelial cell biology.

1990 • 131 citations

Monoclonal antibody against angiotensin-converting enzyme: its use as a marker for murine, bovine, and human endothelial cells.

1982 • 107 citations

Dual site model for the organogenic activity of angiogenin.

1991 • 105 citations

Tissue Distribution and Developmental Expression of the Messenger RNA Encoding Angiogenin

1987 • 104 citations

Inhibitors of Angiogenesis

1991 • 102 citations

The disc angiogenesis system.

1988 • 83 citations

The primary structure of human ribonuclease/angiogenin inhibitor (RAI) discloses a novel highly diversified protein superfamily with a common repetitive module.

1988 • 77 citations

Induction of angiogenesis in vitro by vanadate, an inhibitor of phosphotyrosine phosphatases

1988 • 76 citations

Endothelial Cell Growth Factors and the Vessel Wall

1987 • 73 citations

In Vivo and In Vitro Release of Macromolecules from Polymeric Drug Delivery Systems

1983 • 67 citations

Modulation of mitogenic stimuli by angiogenin correlates with in vitro phosphatidylinositol bisphosphate synthesis.

1989 • 31 citations

Mutagenesis of residues flanking Lys-40 enhances the enzymic activity and reduces the angiogenic potency of angiogenin

1990 • 26 citations

Induction of angiogenesis by mixtures of two angiogenic proteins, angiogenin and acidic fibroblast growth factor, in the chick chorioallantoic membrane

1987 • 19 citations

Organ-specific change inDolichos biflorus lectin binding by myocardial endothelial cells during in vitro cultivation

1993 • 18 citations