Development of a Novel Proteomic Approach for the Detection of Transitional Cell Carcinoma of the Bladder in Urine

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

β-Defensins: Linking Innate and Adaptive Immunity Through Dendritic and T Cell CCR6

1999 • 1,760 citations

New desorption strategies for the mass spectrometric analysis of macromolecules

1993 • 632 citations

Widespread expression of beta‐defensin hBD‐1 in human secretory glands and epithelial cells

1996 • 571 citations

Use of a New Tumor Marker, Urinary NMP22, in the Detection of Occult or Rapidly Recurring Transitional Cell Carcinoma of the Urinary Tract Following Surgical Treatment

1996 • 330 citations

Enteric defensins: antibiotic peptide components of intestinal host defense.

1992 • 310 citations

PROGNOSTIC MARKERS IN BLADDER CANCER: A CONTEMPORARY REVIEW OF THE LITERATURE

1998 • 285 citations

Detection of bladder cancer recurrence by microsatellite analysis of urine

1997 • 285 citations

Proteinchip® surface enhanced laser desorption/ionization (SELDI) mass spectrometry: a novel protein biochip technology for detection of prostate cancer biomarkers in complex protein mixtures

1999 • 264 citations

Integration of mass spectrometry in analytical biotechnology

1991 • 242 citations

Tumor-associated hyaluronic acid: a new sensitive and specific urine marker for bladder cancer.

1997 • 234 citations

Artificial Neural Networks in the Diagnosis and Prognosis of Prostate Cancer: A Pilot Study

1994 • 234 citations

The Human β-Defensin-1 and α-Defensins Are Encoded by Adjacent Genes: Two Peptide Families with Differing Disulfide Topology Share a Common Ancestry

1997 • 212 citations

Proteome profiling of bladder squamous cell carcinomas: identification of markers that define their degree of differentiation.

1997 • 205 citations

Improved detection of recurrent bladder cancer using the bard bta stat test

1997 • 195 citations

Rapid protein display profiling of cancer progression directly from human tissue using a protein biochip

2000 • 156 citations

Loss of adipocyte-type fatty acid binding protein and other protein biomarkers is associated with progression of human bladder transitional cell carcinomas.

1996 • 146 citations

Tumor-derived hyaluronidase: a diagnostic urine marker for high-grade bladder cancer.

1997 • 139 citations

Mechanism of target cytolysis by peptide defensins. Target cell metabolic activities, possibly involving endocytosis, are crucial for expression of cytotoxicity.

1988 • 137 citations

Bactericidal Domain of Lactoferrin: Detection, Quantitation, and Characterization of Lactoferricin in Serum by SELDI Affinity Mass Spectrometry

1998 • 128 citations

From Electrophoretically Separated Protein to Identification: Strategies for Sequence and Mass Analysis

1994 • 124 citations

A Multicenter Trial Evaluation of the Fibrin/Fibrinogen Degradation Products Test for Detection and Monitoring of Bladder Cancer

1997 • 122 citations

Performance characteristics of a new monoclonal antibody test for bladder cancer: ImmunoCyt trade mark.

1997 • 121 citations

Molecular alterations in bladder cancer

1998 • 119 citations

Towards a Comprehensive Database of Proteins From the Urine of Patients With Bladder Cancer

1996 • 110 citations

Overview of Peptide and Protein Analysis by Mass Spectrometry

2010 • 91 citations

Immunohistochemical localization of defensin in human coronary vessels.

1997 • 87 citations

IMMUNOSTAINING OF LEWIS X IN CELLS FROM VOIDED URINE, CYTOPATHOLOGY AND ULTRASOUND FOR NONINVASIVE DETECTION OF BLADDER TUMORS

1998 • 84 citations

Expression of cytokeratin 20 in urinary cytology of patients with bladder carcinoma

1998 • 82 citations

Expression of cytokeratin 20 in urinary cytology of patients with bladder carcinoma.

1998 • 81 citations

Isolation of human intestinal defensins from ileal neobladder urine

1998 • 75 citations

Soluble forms of the adhesion molecule E-cadherin in urine.

1995 • 75 citations

Detection of bladder tumors by immunostaininc of the lewis x antigen in cells from voided urine

1995 • 75 citations

Tumor-Derived Hyaluronidase: A Diagnostic Urine Marker for High-Grade Bladder Cancer

1998 • 75 citations

An enzyme immunoassay for human defensins

1991 • 60 citations

NEURAL NETWORK ANALYSIS OF CLINICOPATHOLOGICAL AND MOLECULAR MARKERS IN BLADDER CANCER

2000 • 60 citations

A comprehensive protein ressource for the study of bladder cancer: http://biobase.dk/cgi-bin/celis

1999 • 59 citations

Generation of a Baculovirus Recombinant Prostate-Specific Membrane Antigen and Its Use in the Development of a Novel Protein Biochip Quantitative Immunoassay

2000 • 51 citations

The Bard<sup>®</sup> BTA Test: Its Mode of Action, Sensitivity and Specificity, Compared to Cytology of Voided Urine, in the Diagnosis of Superficial Bladder Cancer

1998 • 43 citations

Immunohistochemical staining of human alpha-defensin-1 (HNP-1), in the submandibular glands of patients with oral carcinomas.

2000 • 36 citations

Urinary concentrations of the soluble adhesion molecule E-cadherin and total protein in patients with bladder cancer

1999 • 34 citations

Urine cytology, tumour markers and bladder cancer

1998 • 32 citations

Detection of Bladder Cancer Recurrence by Microsatellite Analysis of Urine

1998 • 26 citations

Detection of Onco-Fetal Bladder Antigen in Urine of Patients with Transitional Cell Carcinoma

1987 • 18 citations

Urinary Protein Profiles in Patients with Urothelial Bladder Tumours

1981 • 16 citations

Presence of defensin in epithelial Langerhans cells adjacent to oral carcinomas and precancerous lesions.

2000 • 13 citations

Protein Identification and Characterization by Mass Spectrometry

1998 • 11 citations

Markers of bladder cancer State of the art

2000 • 10 citations

Darwin's Ghost: The Origin of Species Updated

2000 • 9 citations

Overview of Peptide and Protein Analysis by Mass Spectrometry

1997 • 7 citations

Telomerase activity

2000 • 5 citations

Deleted Work

1955 • 0 citations