Distinct DNA binding preferences for the c-Myc/Max and Max/Max dimers

Induction of apoptosis in fibroblasts by c-myc protein

1992 • 2,977 citations

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

1985 • 2,456 citations

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

1987 • 1,792 citations

Max: A Helix-Loop-Helix Zipper Protein That Forms a Sequence-Specific DNA-Binding Complex with Myc

1991 • 1,650 citations

A simple phase-extraction assay for chloramphenicol acyltransferase activity

1988 • 1,006 citations

Differences and Similarities in DNA-Binding Preferences of MyoD and E2A Protein Complexes Revealed by Binding Site Selection

1990 • 957 citations

Sequence-Specific DNA Binding by the c-Myc Protein

1990 • 893 citations

Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis.

1991 • 861 citations

Isolation of Monoclonal Antibodies Specific for Human c-myc Proto-Oncogene Product

1985 • 788 citations

Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites

1993 • 786 citations

Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain

1993 • 723 citations

Mad: A heterodimeric partner for Max that antagonizes Myc transcriptional activity

1993 • 711 citations

Methylation-Sensitive Sequence-Specific DNA Binding by the c-Myc Basic Region

1991 • 596 citations

Association of Myn, the murine homolog of Max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation

1991 • 576 citations

Oncogenic activity of the c-Myc protein requires dimerization with Max

1993 • 543 citations

New light on Myc and Myb. Part II. Myb.

1990 • 487 citations

Myc and Max proteins possess distinct transcriptional activities

1992 • 478 citations

Chimaeras of Myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells

1989 • 475 citations

Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max

1992 • 458 citations

Definition of regions in human c-myc that are involved in transformation and nuclear localization.

1987 • 457 citations

Myc and Max associate in vivo.

1992 • 428 citations

An amino-terminal c-myc domain required for neoplastic transformation activates transcription.

1990 • 413 citations

A sensitive method for the determination of protein-DNA binding specificities

1990 • 346 citations

A series of mammalian expression vectors and characterisation of their expression of a reporter gene in stably and transiently transfected cells

1990 • 313 citations

Max: functional domains and interaction with c-Myc.

1992 • 280 citations

Single amino acid substitutions alter helix-loop-helix protein specificity for bases flanking the core CANNTG motif.

1992 • 199 citations

c-Myc trans-activates the p53 promoter through a required downstream CACGTG motif.

1993 • 186 citations

Determination of the c-MYC DNA-binding site.

1991 • 181 citations

An Amino-Terminal c-Myc Domain Required for Neoplastic Transformation Activates Transcription

1990 • 153 citations

An embryonically expressed gene is a target for c-Myc regulation via the c-Myc-binding sequence.

1992 • 147 citations

Opposite regulation of gene transcription and cell proliferation by c-Myc and Max.

1993 • 146 citations

Myc and Max function as a nucleoprotein complex

1992 • 143 citations

An initiation site of DNA replication with transcriptional enhancer activity present upstream of the c-myc gene.

1988 • 134 citations

Alternative Forms of Max as Enhancers or Suppressors of Myc-Ras Cotransformation

1992 • 130 citations

Myc family oncoproteins function through a common pathway to transform normal cells in culture: cross-interference by Max and trans-acting dominant mutants.

1992 • 129 citations

Sequence-Specific Transcriptional Activation by Myc and Repression by Max

1993 • 124 citations

Definition of Regions in Human c-myc that are Involved in Transformation and Nuclear Localization

1987 • 106 citations

Max and c-Myc/Max DNA-binding activities in cell extracts.

1992 • 94 citations

max encodes a sequence-specific DNA-binding protein and is not regulated by serum growth factors.

1992 • 92 citations

C-MYC: evidence for multiple regulatory functions.

1990 • 79 citations

Biphasic effect of Max on Myc cotransformation activity and dependence on amino- and carboxy-terminal Max functions.

1992 • 59 citations

C-myc and the yeast transcription factor PHO4 share a common CACGTG-binding motif.

1991 • 59 citations

DNA binding activities of c-Myc purified from eukaryotic cells.

1992 • 57 citations

Mutational analysis of Max: role of basic, helix-loop-helix/leucine zipper domains in DNA binding, dimerization and regulation of Myc-mediated transcriptional activation.

1992 • 53 citations

Myc and Max: a putative transcriptional complex in search of a cellular target

1992 • 48 citations

Both the helix-loop-helix and the leucine zipper motifs of c-Myc contribute to its dimerization specificity with Max.

1993 • 38 citations

Gene-regulatory properties of Myc helix-loop-helix/leucine zipper mutants: Max-dependent DNA binding and transcriptional activation in yeast correlates with transforming capacity.

1993 • 29 citations

Protein complexes bearing myc-like antigenicity recognize two distinct DNA sequences.

1992 • 22 citations

Alternative mRNA forms and open reading frames of the max gene.

1993 • 20 citations