Organotypic Keratinocyte Cocultures in Defined Medium with Regular Epidermal Morphogenesis and Differentiation

Calcium-Regulated Differentiation of Normal Human Epidermal Keratinocytes in Chemically Defined Clonal Culture and Serum-Free Serial Culture

1983 • 1,088 citations

Living Tissue Formed in Vitro and Accepted as Skin-Equivalent Tissue of Full Thickness

1981 • 1,042 citations

Large induction of keratinocyte growth factor expression in the dermis during wound healing.

1992 • 603 citations

The mesothelial keratins: A new family of cytoskeletal proteins identified in cultured mesothelial cells and nonkeratinizing epithelia

1982 • 523 citations

Cyclic AMP in relation to proliferation of the Epidermal cell: a new view

1978 • 478 citations

The keratinocyte handbook

1995 • 428 citations

Mutual induction of growth factor gene expression by epidermal-dermal cell interaction

1993 • 401 citations

Transforming growth factor-beta 1 modulates beta 1 and beta 5 integrin receptors and induces the de novo expression of the alpha v beta 6 heterodimer in normal human keratinocytes: implications for wound healing.

1995 • 324 citations

Characterization of human loricrin. Structure and function of a new class of epidermal cell envelope proteins.

1991 • 305 citations

The Formation of Competent Barrier Lipids in Reconstructed Human Epidermis Requires the Presence of Vitamin C

1997 • 302 citations

Keratins (Kl6 and Kl7) as markers of keratinocyte hyperproliferation in psoriasis in vivo and in vitro

1995 • 291 citations

Terminal differentiation of epidermal keratinocytes

1989 • 273 citations

Terminal Epidermal Differentiation of Human Keratinocytes Grown in Chemically Defined Medium on Inert Filter Substrates at the Air-Liquid Interface

1990 • 263 citations

Dynamics of Basement Membrane Formation by Keratinocyte–Fibroblast Interactions in Organotypic Skin Culture

1998 • 256 citations

Retinoic acid improves epidermal morphogenesis

1989 • 239 citations

The Keratinocyte handbook

1994 • 229 citations

New Techniques for the In Vitro Culture of Human Skin Keratinocytes and Perspectives on Their Use for Grafting of Patients With Extensive Burns

1986 • 223 citations

Pretranslational regulation of extracellular matrix macromolecules and collagenase expression in fibroblasts by mechanical forces.

1992 • 204 citations

Epidermis generated in vitro: practical considerations and applications

1991 • 199 citations

Influence of Human Dermal Fibroblasts on Epidermalization

1989 • 192 citations

Defects in the Barrier

1995 • 188 citations

Synthetic peptides corresponding to keratin subunits elicit highly specific antibodies.

1984 • 186 citations

Regulation of proliferation of fibroblasts of low and high population doubling levels grown in collagen lattices

1981 • 170 citations

Fate of human keratinocytes during reepithelialization in an organotypic culture model.

1994 • 169 citations

Activators of the nuclear hormone receptors PPARalpha and FXR accelerate the development of the fetal epidermal permeability barrier.

1997 • 161 citations

Regulation of gene expression by nuclear hormone receptors

1989 • 133 citations

TGF-beta and retinoic acid: regulators of growth and modifiers of differentiation in human epidermal cells.

1990 • 129 citations

Culturing Keratinocytes and Fibroblasts in a Three-Dimensional Mesh Results in Epidermal Differentiation and Formation of a Basal Lamina-Anchoring Zone

1993 • 128 citations

Post-Mitotic Human Dermal Fibroblasts Efficiently Support the Growth of Human Follicular Keratinocytes.

1989 • 119 citations

Mesenchyme-mediated and endogenous regulation of growth and differentiation of human skin keratinocytes derived from different body sites

1990 • 110 citations

Immunofluorescent localization of type IV collagen and laminin during endochondral bone differentiation and regulation by pituitary growth hormone

1980 • 107 citations

Use of Human Skin Recombinants as an in vitro Model for Testing the Irritation Potential of Cutaneous Irritants

1995 • 104 citations

Characterization, Barrier Function, and Drug Metabolism of an In Vitro Skin Model

1993 • 103 citations

Differential modulation of epidermal keratinization in immortalized (HaCaT) and tumorigenic human skin keratinocytes (HaCaT-ras) by retinoic acid and extracellular Ca2+

1993 • 102 citations

Successful Treatment of Chronic Leg Ulcers with Epidermal Equivalents Generated from Cultured Autologous Outer Root Sheath Cells

1996 • 99 citations

Cultured Skin Substitutes: A Review

1996 • 97 citations

Modulation of IL-6 Production of IL-1 Activity by Keratinocyte-Fibroblast Interaction

1993 • 96 citations

The living skin equivalent as a model in vitro for ranking the toxic potential of dermal irritants

1992 • 94 citations

Human Epidermis Reconstructed on Dermal Substrates in vitro: An Alternative to Animals in Skin Pharmacology

1990 • 90 citations

Lipid Supplemented Medium Induces Lamellar Bodies and Precursors of Barrier Lipids in Cultured Analogues of Human Skin

1993 • 89 citations

Improved Barrier Structure Formation in Air-Exposed Human Keratinocyte Culture Systems

1994 • 88 citations

Elastin-Associated Microfibrils (10 nm) in a Three-Dimensional Fibroblast Culture

1991 • 64 citations

Integrin and basement membrane normalization in mouse grafts of human keratinocytes – Implications for epidermal homeostasis

1997 • 64 citations

Culture of reconstructed epidermis in a defined medium at 33° C shows a delayed epidermal maturation, prolonged lifespan and improved stratum corneum

1997 • 63 citations

Mutational analyses of differentiation-dependent human papillomavirus type 18 enhancer elements in epithelial raft cultures of neonatal foreskin keratinocytes.

1997 • 61 citations

Post-mitotic human dermal fibroblasts efficiently support the growth of human follicular keratinocytes

1989 • 61 citations

Type VII Collagen Gene Expression by Human Skin Fibroblasts and Keratinocytes in Culture: Influence of Donor Age and Cytokine Responses

1994 • 60 citations

Correlation between hyperproliferation and suprabasal integrin expression in human epidermis reconstituted in culture

1997 • 55 citations

Minireview: Regulation of Gene Expression by Nuclear Hormone Receptors

1997 • 52 citations

Effect of growth environment on spatial expression of involucrin by human epidermal keratinocytes

1987 • 52 citations

Use of a Serum-Free Epidermal Culture Model to Show Deleterious Effects of Epidermal Growth Factor on Morphogenesis and Differentiation

1995 • 51 citations

Modulation of cellular biosynthetic activity in the retracting collagen lattice.

1987 • 50 citations

Serial cultivation of normal human keratinocytes: A defined system for studying the regulation of growth and differentiation

1992 • 50 citations

Epidermal growth factor and temperature regulate keratinocyte differentiation

1997 • 48 citations

1,25-Dihydroxyvitamin D3 stimulates specifically the last steps of epidermal differentiation of cultured human keratinocytes

1991 • 47 citations

Impaired desquamation in the in vitro reconstructed human epidermis

1996 • 38 citations

Organotypic culture of outer root sheath cells from human hair follicles using a new culture device

1987 • 35 citations

Triglyceride metabolism in human keratinocytes cultured at the air-liquid interface

1995 • 27 citations

Organotypic and epidermal-dermal co-cultures of normal human keratinocytes and dermal cells: Regulation of transforming growth factor α, β1 and β2 mRNA levels

1994 • 27 citations

Fatty Acid Alteration and the Lateral Diffusion of Lipids in the Plasma Membrane of Keratinocytes

1997 • 22 citations

Cell Culture in Pharmaceutical Research

1994 • 13 citations

Cell Culture Models: Reliable Tools in Pharmacotoxicology?

1994 • 8 citations