Progesterone Withdrawal Reduces Paired-Pulse Inhibition in Rat Hippocampus: Dependence on GABA_A Receptor α4 Subunit Upregulation

International Union of Pharmacology: Approaches to the Nomenclature of Voltage-Gated Ion Channels

2003 • 7,170 citations

Steroid Hormone Metabolites Are Barbiturate-Like Modulators of the GABA Receptor

1986 • 2,194 citations

GABA_A Receptor Channels

1994 • 1,948 citations

The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon

1992 • 1,525 citations

International Union of Pharmacology. XV. Subtypes of gamma-aminobutyric acidA receptors: classification on the basis of subunit structure and receptor function.

1998 • 1,204 citations

Decreased Hippocampal Inhibition and a Selective Loss of Interneurons in Experimental Epilepsy

1987 • 1,077 citations

Stress-induced elevations of gamma-aminobutyric acid type A receptor-active steroids in the rat brain.

1991 • 943 citations

Segregation of Different GABA_AReceptors to Synaptic and Extrasynaptic Membranes of Cerebellar Granule Cells

1998 • 829 citations

Selective changes in single cell GABAA receptor subunit expression and function in temporal lobe epilepsy

1998 • 741 citations

Paired‐pulse depression of monosynaptic GABA‐mediated inhibitory postsynaptic responses in rat hippocampus.

1990 • 709 citations

Local and diffuse synaptic actions of GABA in the hippocampus

1993 • 709 citations

Differential Behavioral Effects of Gonadal Steroids in Women with and in Those without Premenstrual Syndrome

1998 • 709 citations

Adaptive regulation of neuronal excitability by a voltage- independent potassium conductance

2001 • 582 citations

GABAA receptor α4 subunit suppression prevents withdrawal properties of an endogenous steroid

1998 • 568 citations

Increased number of synaptic GABAA receptors underlies potentiation at hippocampal inhibitory synapses

1998 • 492 citations

Selective Modulation of Tonic and Phasic Inhibitions in Dentate Gyrus Granule Cells

2002 • 491 citations

The diversity of GABAA receptors

1998 • 489 citations

Three Patterns of Catamenial Epilepsy

1997 • 459 citations

Anxiolytic effects of 3α-hydroxy-5α[β]-pregnan-20-one: endogenous metabolites of progesterone that are active at the GABAA receptor

1991 • 454 citations

Local Generation of Fast Ripples in Epileptic Brain

2002 • 431 citations

EPILEPTIC SEIZURES IN WOMEN RELATED to PLASMA ESTROGEN and PROGESTERONE DURING the MENSTRUAL CYCLE

1976 • 387 citations

Differential synaptic localization of two major gamma-aminobutyric acid type A receptor alpha subunits on hippocampal pyramidal cells.

1996 • 383 citations

Menstrual cycle effects on cortical excitability

1999 • 365 citations

Progesterone metabolite allopregnanolone in women with premenstrual syndrome

1997 • 350 citations

Withdrawal from 3α-OH-5α-Pregnan-20-One Using a Pseudopregnancy Model Alters the Kinetics of Hippocampal GABA_A-Gated Current and Increases the GABA_AReceptor α4 Subunit in Association with Increased Anxiety

1998 • 347 citations

Neurosteroids: 3 alpha-hydroxy-5 alpha-pregnan-20-one and its precursors in the brain, plasma, and steroidogenic glands of male and female rats.

1993 • 344 citations

Hormonally regulated α4β2δ GABAA receptors are a target for alcohol

2002 • 331 citations

Anticonvulsant profile of the progesterone metabolite 5α-pregnan-3α-ol-20-one

1989 • 320 citations

Efficacy and Stability of Quantal GABA Release at a Hippocampal Interneuron–Principal Neuron Synapse

2000 • 286 citations

Chronic benzodiazepine treatment decreases postsynaptic GABA sensitivity

1984 • 279 citations

Functional characterization of human gamma-aminobutyric acidA receptors containing the alpha 4 subunit.

1996 • 259 citations

Cloning, pharmacological characteristics and expression pattern of the rat GABA_A receptor α₄ subunit

1991 • 259 citations

Anxiolytic effect of progesterone is associated with increases in cortical alloprenanolone and GABAA receptor function

1993 • 257 citations

Modulation of the GABA _A receptor by progesterone metabolites

1987 • 245 citations

Neurosteroid regulation of GABAA receptor single‐channel kinetic properties of mouse spinal cord neurons in culture.

1992 • 241 citations

Dependence of the GABAA receptor gating kinetics on the alpha‐subunit isoform: implications for structure‐function relations and synaptic transmission.

1995 • 234 citations

Progesterone alters GABA and glutamate responsiveness: a possible mechanism for its anxiolytic action

1987 • 222 citations

Activation and deactivation rates of recombinant GABA(A) receptor channels are dependent on alpha-subunit isoform

1997 • 213 citations

The neurosteroid 3α,5α-THP has antiseizure and possible neuroprotective effects in an animal model of epilepsy

1995 • 194 citations

Circulating levels of anxiolytic steroids in the luteal phase in women with premenstrual syndrome and in control subjects.

1994 • 178 citations

The Neurosteroid, 3α‐Hydroxy‐5α‐pregnan‐20‐one, Protects against Bicuculline‐Induced Seizures during Ethanol Withdrawal in Rats

1995 • 161 citations

Chronic Intermittent Ethanol Treatment in Rats Increases GABA_A Receptor α4‐Subunit Expression: Possible Relevance to Alcohol Dependence

1997 • 157 citations

Neurosteroid Withdrawal Model of Perimenstrual Catamenial Epilepsy

2001 • 157 citations

Physiological modulation of GABAA receptor plasticity by progesterone metabolites

1999 • 154 citations

Is Premenstrual Dysphoric Disorder a Distinct Clinical Entity?

1999 • 154 citations

Estrogen and progesterone in plasma in relation to premenstrual tension

1974 • 152 citations

Progesterone withdrawal decreases latency to and increases duration of electrified prod burial: A possible rat model of PMS anxiety

1993 • 149 citations

A steroid anesthetic prolongs inhibitory postsynaptic currents in cultured rat hippocampal neurons

1987 • 144 citations

Allopregnanolone affects sleep in a benzodiazepine-like fashion.

1997 • 143 citations

Single channel properties of recombinant GABA_A receptors containing γ2 or δ subtypes expressed with α1 and β3 subtypes in mouse L929 Cells

1997 • 136 citations

Decrease in the Function of the γ‐Aminobutyric Acid‐Coupled Chloride Channel Produced by the Repeated Administration of Pentylenetetrazol to Rats

1990 • 134 citations

Anxiolytic effects of the neuroactive steroid pregnanolone (3α-OH-5β-pregnan-20-one) after microinjection in the dorsal hippocampus and lateral septum

1999 • 133 citations

Paired pulse depression in cultured hippocampal neurons is due to a presynaptic mechanism independent of GABAB autoreceptor activation

1994 • 131 citations

Activation of peripheral mitochondrial benzodiazepine receptors in the hippocampus stimulates allopregnanolone synthesis and produces anxiolytic-like effects in the rat

2000 • 126 citations

Influences of gender, gonadectomy 5 and estrous cycle on GABA/BZ receptors and benzodiazepine responses in rats

1992 • 117 citations

Properties and Plasticity of Paired-Pulse Depression at a Central Synapse

2000 • 109 citations

Chronic Treatment with Diazepam or Abecarnil Differentially Affects the Expression of GABA A Receptor Subunit mRNAs in the Rat Cortex

1996 • 105 citations

Locally applied progesterone metabolites alter neuronal responsiveness in the cerebellum

1987 • 102 citations

The history of benzodiazepine dependence: A review of animal studies

1990 • 100 citations

Seizure Activity Is Increased in Endocrine States Characterized by Decline in Endogenous Levels of the Neurosteroid 3α,5α-THP

1998 • 99 citations

Persistent reduction of GABAA receptor-mediated inhibition in rat hippocampus after chronic intermittent ethanol treatment

1996 • 98 citations

Progesterone withdrawal I: pro-convulsant effects

1998 • 98 citations

Structural Determinants of Fast Desensitization and Desensitization–Deactivation Coupling in GABA_AReceptors

2001 • 97 citations

Pentylenetetrazol‐Induced Seizures Decrease γ‐Aminobutyric Acid‐Mediated Recurrent Inhibition and Enhance Adenosine‐Mediated Depression

1994 • 95 citations

Temporally distinct mechanisms of use-dependent depression at inhibitory synapses in the rat hippocampus in vitro

1994 • 92 citations

Membrane properties and synaptic responses of interneurons located near the stratum lacunosum-moleculare/radiatum border of area CA1 in whole-cell recordings from rat hippocampal slices

1994 • 91 citations

Reduced Excitatory Drive onto Interneurons in the Dentate Gyrus after Status Epilepticus

2001 • 91 citations

Alteration in the Sensitivity of GABA_A Receptors to Allosteric Modulatory Drugs in Rat Hippocampus After Chronic Intermittent Ethanol Treatment

1998 • 90 citations

GABA_A Receptors Containing the α4‐Subunit: Prevalence, Distribution, Pharmacology, and Subunit Architecture In Situ

1997 • 88 citations

Chronic Ethanol Consumption Differentially Alters GABA_A Receptor α1 and α4 Subunit Peptide Expression and GABA_A Receptor‐Mediated ³⁶Cl⁻ Uptake in Mesocorticolimbic Regions of Rat Brain

2001 • 79 citations

Spontaneous interictal-like activity originates in multiple areas of the CA2-CA3 region of hippocampal slices

1994 • 77 citations

Cyclic Withdrawal From Endogenous and Exogenous Progesterone Increases Kainic Acid and Perforant Pathway Induced Seizures

1999 • 74 citations

The anxiolytic effects of intra-hippocampal midazolam are antagonized by intra-septal l-glutamate

2001 • 73 citations

Temporal overlap of excitatory and inhibitory afferent input in guinea‐pig CA1 pyramidal cells

1999 • 71 citations

Evidence for a chronic loss of inhibition in the hippocampus after kindling: electrophysiological studies

1989 • 71 citations

Withdrawal from the endogenous steroid progesterone results in GABAA currents insensitive to benzodiazepine modulation in rat CA1 hippocampus

1995 • 71 citations

Allopregnanolone (THP) Mediates Anesthetic Effects of Progesterone in Rat Brain

1996 • 71 citations

Long-term changes in neocortical activity after chemical kindling with systemic pentylenetetrazole: an in vitro study

1994 • 60 citations

Effects of hippocampal kindling on paired-pulse response in CA1 in vitro

1991 • 59 citations

Antibodies Specific for α‐Subunit Subtypes of GABA_A Receptors Reveal Brain Regional Heterogeneity

1993 • 58 citations

Menstrual cycle interval and ovulation in women with localization-related epilepsy

2001 • 58 citations

Increase in expression of the GABAA receptor α4 subunit gene induced by withdrawal of, but not by long-term treatment with, benzodiazepine full or partial agonists

2001 • 55 citations

Feed‐forward inhibitory potentials and excitatory interactions in guinea‐pig hippocampal pyramidal cells.

1990 • 55 citations

Silent GABA_ASynapses during Flurazepam Withdrawal Are Region-Specific in the Hippocampal Formation

1997 • 54 citations

Hippocampal kindling leads to different changes in paired-pulse depression of local evoked field potentials in CA1 area and in fascia dentata

1992 • 50 citations

How do seizures begin? Clues from hippocampal slices

1988 • 48 citations

Modification of GABA-mediated Inhibition by Various Injectable Anesthetics

1992 • 46 citations

Slow IPSC kinetics, low levels of α1 subunit expression and paired‐pulse depression are distinct properties of neonatal inhibitory GABAergic synaptic connections in the mouse superior colliculus

2001 • 45 citations

Regional distribution of progesterone and 5α-pregnane-3,20-dione in rat brain during progesterone-induced “anesthesia”

1990 • 42 citations

GABA_AReceptor Subunit Composition and Functional Properties of Cl⁻Channels with Differential Sensitivity to Zolpidem in Embryonic Rat Hippocampal Cells

1999 • 41 citations

Benzodiazepine tolerance at GABAergic synapses on hippocampal CA1 pyramidal cells

1999 • 40 citations

Polyclonal Antibodies Directed Against an Epitope Specific for the α4‐Subunit of GABA_A Receptors Identify a 67‐kDa Protein in Rat Brain Membranes

1994 • 37 citations

Unitary synaptic currents between lacunosum‐moleculare interneurones and pyramidal cells in rat hippocampus

2001 • 35 citations

Changes of Hippocampal Glucose Utilization Subsequent to Amygdaloid‐Kindled Generalized Seizures

1991 • 33 citations

Examination of persistent effects of repeated administration of pentylenetrazol on rat hippocampal CA1: evidence from in vitro study on hippocampal slices

1997 • 32 citations

Chronic ethanol treatment reduces inhibition in CA1 of the rat hippocampus

1992 • 31 citations

Sensitivity of the rat hippocampal GABAA receptor α4 subunit to electroshock seizures

1998 • 31 citations

Hippocampal Neurons Express GABA_A Receptor Insensitive to Diazepam in Hyperexcitable Conditions

2000 • 27 citations

To what extent do premenstrual and interictal dysphoric disorder overlap? significance for therapy

1998 • 26 citations

Inhibitory processes in normal and epileptic-like rat hippocampal slices: the role of GABAB receptors

1989 • 26 citations

Differences in the effects of zolpidem and diazepam on recurrent inhibition and long-term potentiation in rat hippocampal slices

1998 • 25 citations

Chronic benzodiazepine treatment of rats induces reduction of paired-pulse inhibition in CA1 region of in vitro hippocampus

1991 • 23 citations

Quantifying the Role of Inhibition in Associative Long-Term Potentiation in Dentate Granule Cells With Computational Models

1997 • 19 citations

The estrous cycle and the olivo-cerebellar circuit

1996 • 19 citations

Disruption of Inhibition in Area CA1 of the Hippocampus in a Rat Model of Temporal Lobe Epilepsy

2001 • 18 citations

Depression of early and late monosynaptic inhibitory postsynaptic potentials in hippocampal CA1 neurons following prolonged benzodiazepine administration: Role of a reduction in Cl driving force

1997 • 17 citations

The estrous cycle and the olivo-cerebellar circuit

1996 • 15 citations

Sensitivity of synaptic GABA_A receptors to allosteric modulators in hippocampal oriens‐alveus interneurons

2001 • 14 citations

Hyperexcitability of hippocampal CA1 region in brain slices after GABA withdrawal

1992 • 13 citations

Harmaline-induced changes in gamma aminobutyric acidA receptor subunit mRNA expression in murine olivocerebellar nuclei

2000 • 12 citations

NONINVASIVE MONITORING OF VASCULAR DYNAMICS BY MEANS OF ELASTIC MODULE

1992 • 2 citations

Deleted Work

1955 • 0 citations