Selective inhibition of constitutive nitric oxide synthase by L-NG-nitroarginine

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Nitric oxide: physiology, pathophysiology, and pharmacology.

1991 • 15,563 citations

Data Reduction and Error Analysis for the Physical Sciences

1969 • 13,865 citations

Nitric oxide as a secretory product of mammalian cells

1992 • 4,437 citations

Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme.

1990 • 3,304 citations

Cloning and Characterization of Inducible Nitric Oxide Synthase from Mouse Macrophages

1992 • 1,914 citations

Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues.

1991 • 1,872 citations

A novel neuronal messenger molecule in brain: The free radical, nitric oxide

1992 • 837 citations

Isoforms of nitric oxide synthase Characterization and purification from different cell types

1991 • 827 citations

Purification and characterization of the cytokine-induced macrophage nitric oxide synthase: an FAD- and FMN-containing flavoprotein.

1991 • 812 citations

Generation of superoxide by purified brain nitric oxide synthase.

1992 • 765 citations

Induction of nitric oxide synthase by cytokines in vascular smooth muscle cells

1990 • 700 citations

Cytokines, endotoxin, and glucocorticoids regulate the expression of inducible nitric oxide synthase in hepatocytes.

1993 • 671 citations

Calmodulin is a subunit of nitric oxide synthase from macrophages.

1992 • 640 citations

Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. Molecular basis for the synergy between interferon-gamma and lipopolysaccharide.

1993 • 623 citations

Nitric oxide synthase is a cytochrome P-450 type hemoprotein

1992 • 617 citations

Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme.

1992 • 616 citations

Protective and pathological roles of nitric oxide in endotoxin shock

1992 • 594 citations

Brain nitric oxide synthase is a biopterin‐ and flavin‐containing multi‐functional oxido‐reductase

1991 • 422 citations

Purification of a soluble isoform of guanylyl cyclase-activating-factor synthase.

1991 • 386 citations

Nitric oxide synthase: Irreversible inhibition by L-N -Nitroarginine in brain and

1991 • 368 citations

Spectral characterization of brain and macrophage nitric oxide synthases. Cytochrome P-450-like hemeproteins that contain a flavin semiquinone radical.

1992 • 344 citations

Brain nitric oxide synthase is a haemoprotein

1992 • 151 citations

Calcium/calmodulin-dependent nitric oxide synthase type I: a biopteroflavoprotein with calcium/calmodulin-independent diaphorase and reductase activities

1992 • 151 citations

Irreversible inactivation of macrophage and brain nitric oxide synthase by L-NG-methylarginine requires NADPH-dependent hydroxylation

1993 • 130 citations

Endothelial nitric oxide synthase is myristylated

1992 • 93 citations

Purification of a distinctive form of endotoxin-induced nitric oxide synthase from rat liver.

1992 • 84 citations

Mechanistic probes of N-hydroxylation of L-arginine by the inducible nitric oxide synthase from murine macrophages

1992 • 79 citations

Identification of inducible calmodulin-dependent nitric oxide synthase in the liver of rats.

1992 • 53 citations