The anti-inflammatory and potential anti-atherogenic effect of insulin: a new paradigm

Effect of angiotensin-converting-enzyme inhibition compared with conventional therapy on cardiovascular morbidity and mortality in hypertension: the Captopril Prevention Project (CAPPP) randomised trial

1999 • 2,051 citations

Randomized trial of insulin-glucose infusion followed by subcutaneous insulin treatment in diabetic patients with acute myocardial infarction (DIGAMI study): Effects on mortality at 1 year

1995 • 1,586 citations

NIDDM as a disease of the innate immune system: association of acute-phase reactants and interleukin-6 with metabolic syndrome X

1997 • 1,246 citations

Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion.

1996 • 795 citations

Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells.

1996 • 735 citations

Detection of premature atherosclerosis by high-resolution ultrasonography in symptom-free hypopituitary adults

1992 • 400 citations

Insulin Stimulates the Synthesis of Plasminogen Activator Inhibitor 1 by the Human Hepatocellular Cell Line Hep G2

1988 • 303 citations

Is Insulin Really a Heart Disease Risk Factor?

1995 • 167 citations

Augmentation of synthesis of plasminogen activator inhibitor type 1 by insulin and insulin-like growth factor type I: implications for vascular disease in hyperinsulinemic states.

1991 • 165 citations

Function and Activation of NF-Kappa B in the Immune System

1994 • 164 citations

Growth Hormone (GH) Treatment Reverses Early Atherosclerotic Changes in GH-Deficient Adults

1999 • 154 citations

Effect of insulin on human aortic endothelial nitric oxide synthase

2000 • 148 citations

Carvedilol Inhibits Reactive Oxygen Species Generation by Leukocytes and Oxidative Damage to Amino Acids

2000 • 141 citations

Vascular smooth muscle cell growth and insulin regulation of mitogen-activated protein kinase in hypertension

1998 • 104 citations

Insulin as a mitogenic factor: Role in the pathogenesis of cardiovascular disease

1991 • 104 citations

Insulin Inhibits the Expression of Intercellular Adhesion Molecule-1 by Human Aortic Endothelial Cells through Stimulation of Nitric Oxide

2000 • 98 citations

Prevention of fat-induced insulin resistance by salicylate

2001 • 81 citations

Glucose and insulin independently reduce the fibrinolytic potential of human vascular smooth muscle cells in culture

1996 • 75 citations

Effect of dexamethasone on reactive oxygen species generation by leukocytes and plasma interleukin-10 concentrations: A pharmacodynamic study

1999 • 68 citations

[Pravastatin and the development of diabetes mellitus. Evidence for a protective treatment effect in the West of Scotland Coronary Prevention Study].

2001 • 67 citations

Effect of hydrocortisone on oxygen free radical generation by mononuclear cells

1998 • 55 citations

Endothelial Cell Adhesion Molecule Expression and Lymphocyte Adhesion to Endothelial Cells: Effect of Nitric Oxide

1997 • 42 citations

Absence of clinically overt atherosclerotic vascular disease and adverse changes in cardiovascular risk factors in 70 patients with insulinoma

1993 • 36 citations

Increased Arterial Intima-Media Thickness in Childhood-Onset Growth Hormone Deficiency

1997 • 35 citations

Femoral Atherosclerosis in Middle-aged Subjects: Association with Cardiovascular Risk Factors and Insulin Resistance

1996 • 29 citations

Insulin and atherogenesis

1992 • 28 citations

What Does Insulin Do to Ras?

1998 • 26 citations

Insulin Potentiates Platelet-Derived Growth Factor Action in Vascular Smooth Muscle Cells

1998 • 24 citations

Hydrocortisone Suppresses Intranuclear Activator-Protein-1 (AP-1) Binding Activity in Mononuclear Cells and Plasma Matrix Metalloproteinase 2 and 9 (MMP-2 and MMP-9)

2001 • 14 citations

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