Mechanically Activated Integrin Switch Controls α ₅ β ₁ Function

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Integrins

2002 • 8,127 citations

Tissue Cells Feel and Respond to the Stiffness of Their Substrate

2005 • 5,909 citations

Tensional homeostasis and the malignant phenotype

2005 • 3,655 citations

Crystal Structure of the Extracellular Segment of Integrin αVβ3 in Complex with an Arg-Gly-Asp Ligand

2002 • 1,571 citations

Focal Contacts as Mechanosensors

2001 • 1,390 citations

Direct observation of catch bonds involving cell-adhesion molecules

2003 • 968 citations

Force Sensing by Mechanical Extension of the Src Family Kinase Substrate p130Cas

2006 • 907 citations

Synergistic Roles for Receptor Occupancy and Aggregation in Integrin Transmembrane Function

1995 • 900 citations

Sensing the environment: a historical perspective on integrin signal transduction

2002 • 855 citations

2.0 Å Crystal Structure of a Four-Domain Segment of Human Fibronectin Encompassing the RGD Loop and Synergy Region

1996 • 621 citations

Comparison of a Structural and a Functional Epitope

1993 • 512 citations

Occupation of the extracellular matrix receptor, integrin, is a control point for myogenic differentiation

1987 • 419 citations

Rapid signal transduction in living cells is a unique feature of mechanotransduction

2008 • 414 citations

A small-molecule inhibitor of skeletal muscle myosin II

2001 • 342 citations

The mechanisms and dynamics of αvβ3 integrin clustering in living cells

2005 • 332 citations

Structure of integrin 5 1 in complex with fibronectin

2003 • 332 citations

Focal adhesions as mechanosensors: A physical mechanism

2005 • 292 citations

FimH Forms Catch Bonds That Are Enhanced by Mechanical Force Due to Allosteric Regulation

2008 • 215 citations

Force Required to Break α5β1Integrin-Fibronectin Bonds in Intact Adherent Cells Is Sensitive to Integrin Activation State

1998 • 152 citations

A Novel Mode for Integrin-mediated Signaling: Tethering Is Required for Phosphorylation of FAK Y397

2003 • 142 citations

Mapping functional residues onto integrin crystal structures

2003 • 85 citations

Rac-dependent cyclin D1 gene expression regulated by cadherin- and integrin-mediated adhesion

2008 • 62 citations

Quantitative Measurements of Integrin‐Mediated Adhesion to Extracellular Matrix

2007 • 46 citations