YY1 Represses Vitamin D Receptor-Mediated 25-Hydroxyvitamin D3 24-Hydroxylase Transcription: Relief of Repression by CREB-Binding Protein

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily

1995 • 2,390 citations

The CBP co-activator is a histone acetyltransferase

1996 • 1,773 citations

Nuclear Receptor Coactivator ACTR Is a Novel Histone Acetyltransferase and Forms a Multimeric Activation Complex with P/CAF and CBP/p300

1997 • 1,472 citations

The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed

1998 • 1,391 citations

The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function

1997 • 1,300 citations

Steroid receptor coactivator-1 is a histone acetyltransferase

1997 • 1,245 citations

Transcriptional repression by YY1, a human GLI-Krüippel-related protein, and relief of repression by adenovirus E1A protein

1991 • 1,023 citations

GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors.

1996 • 702 citations

Transcription Factor-Specific Requirements for Coactivators and Their Acetyltransferase Functions

1998 • 639 citations

Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3

1996 • 541 citations

RNA Helicase A Mediates Association of CBP with RNA Polymerase II

1997 • 532 citations

Identification of a DNA sequence responsible for binding of the 1,25-dihydroxyvitamin D3 receptor and 1,25-dihydroxyvitamin D3 enhancement of mouse secreted phosphoprotein 1 (SPP-1 or osteopontin) gene expression.

1990 • 467 citations

YY1 is an initiator sequence-binding protein that directs and activates transcription in vitro

1991 • 465 citations

Increasing the Complexity of Coactivation in Nuclear Receptor Signaling

1999 • 449 citations

Recruitment of CBP/p300 by the IFNβ Enhanceosome Is Required for Synergistic Activation of Transcription

1998 • 433 citations

Isolation and Characterization of cDNAs Corresponding to an Additional Member of the Human Histone Deacetylase Gene Family

1997 • 431 citations

Deficient Mineralization of Intramembranous Bone in Vitamin D-24-Hydroxylase-Ablated Mice Is Due to Elevated 1,25-Dihydroxyvitamin D and Not to the Absence of 24,25-Dihydroxyvitamin D*

2000 • 321 citations

An analysis of genes regulated by the multi-functional transcriptional regulator Yin Yang-1

1994 • 306 citations

Relief of YY1 transcriptional repression by adenovirus E1A is mediated by E1A-associated protein p300.

1995 • 305 citations

Cloning of the human 1α,25-dihydroxyvitamin D-3 24-hydroxylase gene promoter and identification of two vitamin D-responsive elements

1995 • 281 citations

TATA-binding protein-independent initiation: YY1, TFIIB, and RNA polymerase II direct basal transcription on supercoiled template DNA

1994 • 275 citations

Cloning of a human gene encoding the general transcription initiation factor IIB

1991 • 274 citations

Calcitroic acid, end product of renal metabolism of 1,25-dihydroxyvitamin D3 through the C-24 oxidation pathway

1989 • 245 citations

Genomic mechanisms involved in the pleiotropic actions of 1,25-dihydroxyvitamin D3

1996 • 233 citations

Displacement of BrdUrd-induced YY1 by serum response factor activates skeletal alpha-actin transcription in embryonic myoblasts.

1992 • 221 citations

Transcription factor TFIIB and the vitamin D receptor cooperatively activate ligand-dependent transcription.

1995 • 212 citations

Characterization of the Transcriptional Regulator YY1

1997 • 202 citations

Yin-yang 1 activates the c-myc promoter.

1993 • 187 citations

The Nuclear Factor YY1 Suppresses the Human Gamma Interferon Promoter through Two Mechanisms: Inhibition of AP1 Binding and Activation of a Silencer Element

1996 • 171 citations

Functional antagonism between YY1 and the serum response factor.

1992 • 168 citations

Evidence for Ligand-Dependent Intramolecular Folding of the AF-2 Domain in Vitamin D Receptor-Activated Transcription and Coactivator Interaction

1997 • 154 citations

The nuclear factor YY1 participates in repression of the beta-casein gene promoter in mammary epithelial cells and is counteracted by mammary gland factor during lactogenic hormone induction.

1994 • 141 citations

Human TAF(II)135 potentiates transcriptional activation by the AF-2s of the retinoic acid, vitamin D3, and thyroid hormone receptors in mammalian cells.

1997 • 141 citations

p300 Mediates Transcriptional Stimulation by the Basic Helix-Loop-Helix Activators of the Insulin Gene

1998 • 139 citations

The rat casein multigene family. Fine structure and evolution of the beta-casein gene.

1985 • 127 citations

Transcriptional Synergism between Vitamin D-responsive Elements in the Rat 25-Hydroxyvitamin D3 24-Hydroxylase (CYP24) Promoter

1996 • 122 citations

YY1 represses rat serum amyloid A1 gene transcription and is antagonized by NF-kappa B during acute-phase response.

1994 • 116 citations

DNA target selectivity by the vitamin D3 receptor: mechanism of dimer binding to an asymmetric repeat element.

1993 • 110 citations

YY1 regulates vitamin D receptor/retinoid X receptor mediated transactivation of the vitamin D responsive osteocalcin gene

1997 • 91 citations

Different Regulatory Sequences Control Creatine Kinase-M Gene Expression in Directly Injected Skeletal and Cardiac Muscle

1993 • 91 citations

YY1 represses beta-casein gene expression by preventing the formation of a lactation-associated complex.

1994 • 84 citations

Isolation and structural analysis of the mouse β-casein gene

1989 • 77 citations

Protein-DNA interactions in the epsilon-globin gene silencer.

1993 • 76 citations

The N-Terminal Domain of Transcription Factor IIB Is Required for Direct Interaction with the Vitamin D Receptor and Participates in Vitamin D-Mediated Transcription

1997 • 76 citations

Retinoid X Receptor:Vitamin D₃ Receptor Heterodimers Promote Stable Preinitiation Complex Formation and Direct 1,25-Dihydroxyvitamin D₃-Dependent Cell-Free Transcription

1997 • 74 citations

YY1 Is a Negative Regulator of Transcription of Three Sterol Regulatory Element-binding Protein-responsive Genes

1999 • 58 citations

Different regulatory sequences control creatine kinase-M gene expression in directly injected skeletal and cardiac muscle.

1993 • 48 citations

Lysine 246 of the Vitamin D Receptor Is Crucial for Ligand-dependent Interaction with Coactivators and Transcriptional Activity

1999 • 45 citations

Selective Use of TBP and TFIIB Revealed by a TATA-TBP-TFIIB Array with Altered Specificity

1997 • 39 citations

Expression of 25(OH)D₃24-hydroxylase in distal nephron: coordinate regulation by 1,25(OH)₂D₃and cAMP or PTH

1999 • 38 citations

Thyroid Hormone Receptor Does Not Heterodimerize with the Vitamin D Receptor but Represses Vitamin D Receptor-Mediated Transactivation

1998 • 27 citations

Identification and Characterization of a Novel Transcriptional Activation Domain in the CREB-binding Protein

1996 • 23 citations