Distribution of [3H]zolpidem binding sites in relation to messenger RNA encoding the α1, β2 and γ2 subunits of GABAA receptors in rat brain

Sequence and functional expression of the GABAA receptor shows a ligand-gated receptor super-family

1987 • 1,621 citations

The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon

1992 • 1,525 citations

Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology

1989 • 1,283 citations

Molecular biology of GABA _A receptors

1990 • 947 citations

Type I and Type II GABA _A -Benzodiazepine Receptors Produced in Transfected Cells

1989 • 716 citations

The effect of subunit composition of rat brain GABAA receptors on channel function

1990 • 592 citations

Structural and functional basis for GABAA receptor heterogeneity

1988 • 590 citations

Functional properties of recombinant rat GABAA receptors depend upon subunit composition

1990 • 557 citations

Two novel GABAA receptor subunits exist in distinct neuronal subpopulations

1989 • 532 citations

Some properties of brain specific benzodiazepine receptors: New evidence for multiple receptors

1979 • 412 citations

GABAA receptor beta subunit heterogeneity: functional expression of cloned cDNAs.

1989 • 404 citations

GABAA receptors: ligand-gated Cl− ion channels modulated by multiple drug-binding sites

1992 • 382 citations

Comparative molecular neuroanatomy of cloned GABA_Areceptor subunits in the rat CNS

1992 • 382 citations

Localization of D1 dopamine receptor mRNA in brain supports a role in cognitive, affective, and neuroendocrine aspects of dopaminergic neurotransmission.

1991 • 354 citations

Ethanol sensitivity of the GABAA receptor expressed in xenopus oocytes requires 8 amino acids contained in the γ2L subunit

1991 • 353 citations

Five subtypes of type A gamma-aminobutyric acid receptors identified in neurons by double and triple immunofluorescence staining with subunit-specific antibodies.

1992 • 346 citations

Influence of recombinant gamma-aminobutyric acid-A receptor subunit composition on the action of allosteric modulators of gamma-aminobutyric acid-gated Cl- currents.

1991 • 338 citations

Function and pharmacology of multiple GABAA receptor subunits

1991 • 292 citations

Zolpidem, a novel nonbenzodiazepine hypnotic. I. Neuropharmacological and behavioral effects.

1986 • 274 citations

GABAA receptor subtypes: autoradiographic comparison of GABA, benzodiazepine, and convulsant binding sites in the rat central nervous system.

1990 • 250 citations

Multiple benzodiazepine receptors: no reason for anxiety

1992 • 233 citations

Topographic patterns of brain activity in response to swim stress: assessment by 2-deoxyglucose uptake and expression of Fos-like immunoreactivity

1993 • 221 citations

GABAA receptors display association of γ2-subunit with α1- and β2/3-subunits

1991 • 218 citations

Gamma-aminobutyric acidA receptor structure and function.

1992 • 208 citations

Cloning of cDNA sequences encoding human alpha 2 and alpha 3 gamma-aminobutyric acidA receptor subunits and characterization of the benzodiazepine pharmacology of recombinant alpha 1-, alpha 2-, alpha 3-, and alpha 5-containing human gamma-aminobutyric acidA receptors.

1993 • 201 citations

Generation of Two Forms of the γ‐Aminobutyric Acid_A Receptor γ‐₂‐Subunit in Mice by Alternative Splicing

1991 • 196 citations

GABAA receptor subtypes immunopurified from rat brain with α subunit-specific antibodies have unique pharmacological properties

1991 • 195 citations

Ethanol potentiates GABA- and glycine-induced chloride currents in chick spinal cord neurons

1988 • 192 citations

The GABAA Receptor Family: Molecular and Functional Diversity

1990 • 187 citations

Chronic ethanol administration alters gamma-aminobutyric acid, pentobarbital and ethanol-mediated 36Cl- uptake in cerebral cortical synaptoneurosomes.

1988 • 184 citations

Ethanol potentiation of GABA_A receptors requires phosphorylation of the alternatively spliced variant of the γ2 subunit

1992 • 178 citations

Prolonged ethanol inhalation decreases gamma-aminobutyric acidA receptor alpha subunit mRNAs in the rat cerebral cortex.

1991 • 169 citations

Functional characteristics and sites of gene expression of the alpha 1, beta 1, gamma 2-isoform of the rat GABAA receptor

1990 • 156 citations

gamma-Aminobutyric acid type A receptor point mutation increases the affinity of compounds for the benzodiazepine site.

1991 • 152 citations

Molecular basis for regionally specific action of ethanol on gamma-aminobutyric acidA receptors: generalization to other ligand-gated ion channels.

1993 • 149 citations

Chronic ethanol and pentobarbital administration in the rat: Effects on GABAA receptor function and expression in brain

1990 • 141 citations

Autoradiographic Localization of [³H]Zolpidem Binding Sites in the Rat CNS: Comparison with the Distribution of [³H]Flunitrazepam Binding Sites

1987 • 121 citations

Site-specific enhancement of gamma-aminobutyric acid-mediated inhibition of neural activity by ethanol in the rat medial septal area.

1990 • 118 citations

Region‐specific expression of the mRNAs encoding β subunits (β₁, β₂, and β₃) of GABA_A receptor in the rat brain

1991 • 116 citations

Mapping of brain areas containing RNA homologous to cDNAs encoding the alpha and beta subunits of the rat GABAA gamma-aminobutyrate receptor.

1988 • 112 citations

GABAA-receptor expressed from rat brain α- and β-subunit cDNAs displays potentiation by benzodiazepine receptor ligands

1990 • 99 citations

Differential effects of chronic ethanol administration on GABAA receptor α1 and α6 subunit mRNA levels in rat cerebellum

1992 • 98 citations

Comparative autoradiographic distribution of central ω (benzodiazepine) modulatory site subtypes with high, intermediate and low affinity for zolpidem and alpidem

1993 • 93 citations

In vivo interaction of zolpidem with central benzodiazepine (BZD) binding sites (as labeled by [3H]Ro 15-1788) in the mouse brain. Preferential affinity of zolpidem for the omega 1 (BZD1) subtype.

1988 • 91 citations

GABA_A Receptor Subtypes: Ligand Binding Heterogeneity Demonstrated by Photoaffinity Labeling and Autoradiography

1993 • 91 citations

Distinct Developmental Patterns of Expression of Rat ?₁, ?₅, ?_2S, and ?_12L?-Aminobutyric Acid_AReceptor Subunit mRNAs In Vivo and In Vitro

1992 • 88 citations

Pharmacologic significance of the structural heterogeneity of the GABAA receptor-chloride ion channel complex.

1991 • 85 citations

Electrophysiological evidence that ethanol alters function of medial septal area without affecting lateral septal function.

1990 • 85 citations

Inverse but not full benzodiazepine agonists modulate recombinant α6β2γ2 GABAA receptors in transfected human embryonic kidney cells

1991 • 62 citations

Various proteins from rat brain, specifically and irreversibly labeled by [3H]flunitrazepam, are distinct α-subunits of the GABA-benzodiazepine receptor complex

1988 • 62 citations

Differential localization of type I and type II benzodiazepine binding sites in substantia nigra

1983 • 61 citations

Localization of GABAA receptor α-subunit mRNAs in relation to receptor subtypes

1989 • 59 citations

Identification of the α₃‐subunit in the GABA_A receptor purified from bovine brain

1989 • 53 citations

Ethanol potentiates gamma-aminobutyric acid-mediated inhibition in the inferior colliculus: evidence for local ethanol/gamma-aminobutyric acid interactions.

1991 • 51 citations

β-carboline-3-carboxylate-t-butyl ester: A selective BZ1 benzoiazepine receptor antagonist

1984 • 46 citations

gamma-Aminobutyric acidA receptor heterogeneity in rat central nervous system: studies with clonazepam and other benzodiazepine ligands.

1991 • 42 citations

Autoradiographic analysis of benzodiazepine binding in entorhinal-kindled rat brains

1989 • 40 citations

The neuroanatomical specificity of ethanol action on ligand-gated ion channels: a hypothesis.

1993 • 30 citations

Differential properties of type I and type II benzodiazepine receptors in mammalian CNS neurones

1993 • 29 citations

The region-specific expression of the mRNAs encoding β subunits (β[1], β[2], and β[3]) of GABA[A] receptor in the rat brain

1990 • 29 citations

Comparison of Benzodiazepine Receptors in Cerebellum and Inferior Colliculus

1986 • 28 citations

Selective affinity of the benzodiazepines quazepam and 2-oxo-quazepam for BZ1 binding site and demonstration of 3H-2-oxo-quazepam as a BZ1 selective radioligand

1988 • 27 citations

Rat pituitary cells selectively express mRNA encoding the short isoform of the γ2 GABAA receptor subunit

1992 • 15 citations

Evidence for more than two central benzodiazepine receptors in rat spinal cord

1992 • 13 citations

Binding sites for [3H]2-OXO-quazepam in the brain of the cat: Evidence for heterogeneity of benzodiazepine recognition sites

1989 • 9 citations

Localization and functional expression of alternatively spliced forms of the GABAA receptor γ2 subunit

1991 • 6 citations