Age-related impairments in spatial memory are independent of those in sensorimotor skills

The Cholinergic Hypothesis of Geriatric Memory Dysfunction

1982 • 5,422 citations

Alzheimer's Disease and Senile Dementia: Loss of Neurons in the Basal Forebrain

1982 • 3,563 citations

Alzheimer's Disease: A Disorder of Cortical Cholinergic Innervation

1983 • 3,028 citations

Spatial localization does not require the presence of local cues

1981 • 2,665 citations

Spatial learning and motor deficits in aged rats

1984 • 509 citations

Transplanted adrenal chromaffin cells in rat brain reduce lesion-induced rotational behaviour

1981 • 415 citations

Intrahippocampal Septal Grafts Ameliorate Learning Impairments in Aged Rats

1984 • 369 citations

An evaluation of spatial information processing in aged rats.

1987 • 353 citations

Learning and memory deficits after lesions of the nucleus basalis magnocellularis: Reversal by physostigmine

1985 • 305 citations

Regional changes in brain glucose metabolism reflect cognitive impairments in aged rats

1984 • 246 citations

Disruption of central cholinergic systems in the rat by basal forebrain lesions or atropine: Effects on feeding, sensorimotor behaviour, locomotor activity and spatial navigation

1985 • 242 citations

Animal Models of Declining Memory in the Aged: Short-term and Spatial Memory in the Aged Rat

1980 • 227 citations

Cholinergic septal grafts into the hippocampal formation improve spatial learning and memory in aged rats by an atropine-sensitive mechanism

1986 • 224 citations

Age and neurochemical correlates of radial maze performance in rats

1981 • 217 citations

Movement Disorders of Aged Rats: Reversal by Dopamine Receptor Stimulation

1979 • 207 citations

Cholinergic ventral forebrain grafts into the neocortex improve passive avoidance memory in a rat model of Alzheimer disease.

1985 • 190 citations

Aged Rats: Recovery of Motor Impairments by Intrastriatal Nigral Grafts

1983 • 162 citations

Recovery of neocortical choline acetyltransferase activity following ibotenic acid injection into the nucleus basalis of Meynert in rats

1984 • 151 citations

Aged rats need a preserved complement of perforated axospinous synapses per hippocampal neuron to maintain good spatial memory

1986 • 149 citations

Quantitative histochemistry of brain acetylcholinesterase and learning rate in the aged rat

1986 • 136 citations

Psychomotor performance in the senescent rodent: reduction of deficits via striatal dopamine receptor up-regulation

1983 • 135 citations

Impairment in T-maze reinforced alternation performance following nucleus basalis magnocellularis lesions in rats

1984 • 116 citations

Noradrenergic changes and memory loss in aged mice

1985 • 97 citations

Effects of bilateral ibotenate-induced lesions of the nucleus basalis magnocellularis upon selective cholinergic biochemical markers in the rat anterior cerebral cortex

1985 • 88 citations

Electrophysiological Markers of Aging and Memory Loss in Rats^a

1985 • 81 citations

Assessing the predictive validity of psychomotor tests as measures of biological age in mice

1986 • 65 citations

Sensorimotor Disturbances in the Aging Rodent

1982 • 64 citations

Discrimination learning requiring different memory components in rats: Age and neurochemical comparisons.

1985 • 60 citations

Dopamine-rich transplants in experimental parkinsonism

1983 • 54 citations

Discrimination learning requiring different memory components in rats: Age and neurochemical comparisons.

1985 • 51 citations

Age-dependent correlation of motor performance with neurotransmitter synthetic enzyme activities in mice

1983 • 19 citations

Animal behavioral models in biogerontology

1984 • 9 citations

Behavioral kinetics: Dynamics of the unconditioned response to footshock

1982 • 7 citations

Human Cerebral Metabolism: Studies in Normal Subjects and Patients with Dementia and Amnesia^a

1985 • 6 citations