Interleukin 4 and Interferon Gamma Production in Restimulated CD4⁺ and CD8⁺ Cells Indicates Memory Type Responsiveness

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

Xenogeneic Monoclonal Antibodies to Mouse Lymphoid Differentiation Antigens*

1979 • 1,989 citations

Interferon-γ and B Cell Stimulatory Factor-1 Reciprocally Regulate Ig Isotype Production

1987 • 1,936 citations

Identification of a monoclonal antibody specific for a murine T3 polypeptide.

1987 • 1,644 citations

Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen‐Reactivity

1983 • 1,040 citations

Two types of mouse helper T-cell clone

1987 • 813 citations

Human naive and memory T cells

1988 • 793 citations

The cytokine network

1989 • 785 citations

Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1

1985 • 749 citations

Simultaneous production of IL-2, IL-4, and IFN-gamma by activated human CD4+ and CD8+ T cell clones.

1988 • 509 citations

Distinction of virgin and memory T lymphocytes. Stable acquisition of the Pgp-1 glycoprotein concomitant with antigenic stimulation.

1987 • 505 citations

A new murine CD4+ T cell subset with an unrestricted cytokine profile.

1989 • 374 citations

A functional dichotomy in CD4+ T lymphocytes

1988 • 369 citations

Interleukin 4 induces synthesis of IgE and IgG4 in human B cells

1989 • 300 citations

Lymphokine and nonlymphokine mRNA levels in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin A.

1986 • 293 citations

Heterogeneity of helper/inducer T lymphocytes. I. Lymphokine production and lymphokine responsiveness.

1987 • 289 citations

Regulation of T‐Cell Activation; Differences among T‐Cell Subsets

1989 • 271 citations

γ-Interferon is one of several direct B cell-maturing lymphokines

1984 • 237 citations

A monoclonal antibody to murine CD45R distinguishes CD4 T cell populations that produce different cytokines

1989 • 237 citations

Regulation of Cytokine Gene Expression

1988 • 234 citations

Role of γ-interferon in antibody-producing responses

1984 • 203 citations

Simultaneous production of interleukin 2, interleukin 4 and interferon‐γ by activated human blood lymphocytes

1990 • 165 citations

Frequencies of IL-2- and IL-4-secreting T cells in naive and antigen-stimulated lymphocyte populations.

1988 • 164 citations

The Cellular Basis of T-Cell Memory

1989 • 161 citations

Phenotypic and functional heterogeneity of CD4+ T cells

1988 • 142 citations

Restricted production of interleukin 4 by activated human T cells.

1988 • 141 citations

Regulation by interferons of the local inflammatory response to bacterial lipopolysaccharide.

1987 • 140 citations

Signal requirements for T lymphocyte activation. I. Replacement of macrophage function with phorbol myristic acetate.

1979 • 134 citations

Enhanced responsiveness of human memory T cells to CD2 and CD3 receptor‐mediated activation

1989 • 124 citations

The Role of IL4 and IL5: Characterization of a Distinct Helper T Cell Subset that makes IL4 and IL5 (Th2) and Requires Priming before Induction of Lymphokine Secretion

1988 • 123 citations

Analysis by in situ hybridization of cells expressing mRNA for interleukin 4 in the developing thymus and in peripheral lymphocytes from mice.

1988 • 78 citations

Gamma‐Interferon is Produced by CD3+ and CD3‐ Lymphocytes

1987 • 64 citations

In vitro production and cellular origin of murine type II interferon.

1979 • 61 citations

Differential activation of cytokine genes in normal CD4‐bearing T cells is stimulus dependent

1989 • 60 citations

Antigen-reactive cloned helper T cells. I. Unresponsiveness to antigenic restimulation develops after stimulation of cloned helper T cells.

1984 • 53 citations

Concomitant production of different lymphokines in activated T cells

1988 • 52 citations

An Atlas of Immunofluorescence in Cultured Cells

1985 • 52 citations

An atlas of immunofluorescence in cultured cells

1986 • 49 citations

Interleukin 2, 4 and 5 are sequentially produced in mitogen‐stimulated murine spleen cell cultures

1990 • 35 citations

Influence of activating stimulus on functional phenotype: interleukin 2 mRNA accumulation differentially induced by ionophore and receptor ligands in subsets of murine T cells.

1988 • 32 citations

Positively selected Lyt-2+ and Lyt-2- mouse T lymphocytes are comparable, after Con A stimulation, in release of IL 2 and of lymphokines acting on B cells, macrophages, and mast cells, but differ in interferon production.

1983 • 31 citations

Lymphokine production by murine T cells in the mixed leukocyte reaction.

1988 • 27 citations

Detection of Individual Interleukin 4‐ and Gamma Interferon‐Producing Murine Spleen Cells after Activation with T‐Cell Mitogens

1989 • 20 citations

IL-4 and IL-5: biology and genetics.

1988 • 5 citations