Barium Evokes Glutamate Release from Rat Brain Synaptosomes by Membrane Depolarization: Involvement of K⁺, Na⁺, and Ca²⁺ Channels

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Diversity and ubiquity of K channels

1988 • 1,342 citations

Intraterminal injection of synapsin I or calcium/calmodulin-dependent protein kinase II alters neurotransmitter release at the squid giant synapse.

1985 • 636 citations

The pharmacology of potassium channels and their therapeutic potential

1988 • 582 citations

The cytoskeletal architecture of the presynaptic terminal and molecular structure of synapsin 1.

1989 • 500 citations

Calcium‐Dependent and‐Independent Release of Glutamate from Synaptosomes Monitored by Continuous Fluorometry

1987 • 459 citations

Mechanism of Activation of a Cyclic Adenosine 3′:5′-Monophosphate Phosphodiesterase from Bovine Heart by Calcium Ions

1973 • 444 citations

A rapid method for isolation of synaptosomes on Percoll gradients

1986 • 421 citations

Energy transduction in intact synaptosomes. Influence of plasma-membrane depolarization on the respiration and membrane potential of internal mitochondria determined in situ

1980 • 391 citations

Toxins in the characterization of potassium channels

1989 • 340 citations

The organization of cytoplasm at the presynaptic active zone of a central nervous system synapse

1988 • 340 citations

Membranes—A series of advances

1974 • 335 citations

Repetitive Action Potentials in Isolated Nerve Terminals in the Presence of 4‐Aminopyridine: Effects on Cytosolic Free Ca²⁺ and Glutamate Release

1989 • 297 citations

Calcium/calmodulin-dependent protein kinase II increases glutamate and noradrenaline release from synaptosomes

1990 • 284 citations

Multiple phosphorylation sites in protein I and their differential regulation by cyclic AMP and calcium.

1979 • 284 citations

The Synapsins

1990 • 268 citations

Membrane Currents Carried by Ca, Sr, and Ba in Barnacle Muscle Fiber During Voltage Clamp

1974 • 241 citations

Ca2+-dependent and Ca2+- independent glutamate release, energy status and cytosolic free Ca2+ concentration in isolated nerve terminals following metabolic inhibition: Possible relevance to hyoglycaemia and anoxia

1988 • 228 citations

Regulation of transmitter release at the squid giant synapse by presynaptic delayed rectifier potassium current.

1990 • 226 citations

Characterization of the Bradykinin-stimulated Calcium Influx Pathway of Cultured vascular Endothelial Cells

1989 • 224 citations

Central action of dendrotoxin: selective reduction of a transient K conductance in hippocampus and binding to localized acceptors.

1986 • 221 citations

Comparative measurements of membrane potentials with microelectrodes and voltage-sensitive dyes

1984 • 205 citations

Synapsin I: A synaptic vesicle-associated neuronal phosphoprotein

1986 • 168 citations

Transmitter Glutamate Release from Isolated Nerve Terminals: Evidence for Biphasic Release and Triggering by Localized Ca²⁺

1991 • 158 citations

Initial release of [3H]dopamine from rat striatal synaptosomes: correlation with calcium entry

1983 • 135 citations

Protein phosphorylation in nerve terminals: comparison of calcium/calmodulin-dependent and calcium/diacylglycerol-dependent systems

1988 • 122 citations

Divalent cations differentially support transmitter release at the squid giant synapse.

1984 • 119 citations

The effects of alkaline earths and other divalent cations on adrenal medullary secretion

1964 • 119 citations

Influx of calcium, strontium, and barium in presynaptic nerve endings.

1982 • 105 citations

On the role of barium in supporting the asynchronous release of acetylcholine quanta by motor nerve impulses.

1978 • 96 citations

Stimulant Action of Barium on the Adrenal Medulla

1964 • 93 citations

Affinity of heavy metal ions to intracellular Ca2+-binding proteins

1986 • 93 citations

Cytoplasmic architecture of the axon terminal: Filamentous strands specifically associated with synaptic vesicles

1991 • 93 citations

Dendrotoxin, 4‐Aminopyridine, and β‐Bungarotoxin Act at Common Loci but by Two Distinct Mechanisms to Induce Ca²⁺‐Dependent Release of Glutamate from Guinea‐Pig Cerebrocortical Synaptosomes

1989 • 91 citations

Potassium channels in isolated presynaptic nerve terminals from rat brain.

1985 • 86 citations

Barium ions enter chromaffin cells via voltage-dependent calcium channels and induce secretion by a mechanism independent of calcium

1989 • 67 citations

The effects of strontium and barium ions at synapses in sympathetic ganglia.

1977 • 59 citations

Effects of polyvalent cations on stimulus-coupled secretion of (14C)-gamma-aminobutyric acid from isolated brain synaptosomes.

1974 • 39 citations

Strontium, barium, and manganese metabolism in isolated presynaptic nerve terminals

1987 • 34 citations

Membrane potentials associated with Ca-induced K conductance in human red blood cells: Studies with a fluorescent oxonol dye, WW 781

1983 • 33 citations

Depolarization-dependent protein phosphorylation in rat cortical synaptosomes: The effects of calcium, strontium and barium

1983 • 33 citations

Presynaptic Mechanism of Action of 4‐Aminopyridine: Changes in Intracellular Free Ca²⁺ Concentration and Its Relationship to B‐50 (GAP‐43) Phosphorylation

1991 • 30 citations

Calmodulin‐ and protein phosphorylation‐independent release of catecholamines from PC‐12 cells

1988 • 20 citations

Effects of Calcium, Strontium, and Barium Ions on Phosphorylation of Hippocampal Proteins In Vitro

1984 • 19 citations

Barium and strontium can substitute for calcium in noradrenaline output induced by excess potassium in the guinea‐pig.

1980 • 19 citations

Transmitter release at mouse motor nerve terminals mediated by temporary accumulation of intracellular barium.

1988 • 19 citations

Single Ca²⁺ entry and transmitter release systems at the neuromuscular synapse

1988 • 18 citations

Mechanism of depolarization of rat cortical synaptosomes at submicromolar external Ca2+ activity. The use of Ca2+ buffers to control the synaptosomal membrane potential

1985 • 18 citations

Barium distinguishes separate calcium targets for synthesis and secretion of peptides in neuroendocrine cells

1987 • 16 citations

Barium-evoked release of catecholamines from digitonin-permeabilized adrenal medullary cells

1986 • 15 citations

Ba2+-induced atp release from adrenal medullary chromaffin cells is mediated by Ba2+ entry through both voltage- and receptor-gated Ca2+ channels

1988 • 15 citations

Pharmacological study on Ba2+-stimulated catecholamine secretion from cultured bovine adrenal chromaffin cells: Possible relation of Ba2+ action to Ca2+-activated secretory mechanism.

1991 • 11 citations

Cobalt-sensitive and dihydropyridine-insensitive stimulation of dopamine release from tuberoinfundibular neurons by high extracellular concentrations of barium ions

1989 • 7 citations

Metal cation induced activation of calmodulin is a function of ionic radii

1983 • 7 citations

Statistical evidence for non-random clustering of synaptic vesicles associated with filamentous interconnections

1988 • 6 citations