Regulation of Vascular Growth and Regression by Matrix Metalloproteinases in the Rat Aorta Model of Angiogenesis

Angiogenesis in cancer, vascular, rheumatoid and other disease

1995 • 7,717 citations

Angiogenic Factors

1987 • 3,702 citations

A matrix metalloproteinase expressed on the surface of invasive tumour cells

1994 • 2,561 citations

Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques.

1994 • 2,497 citations

MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes

1998 • 1,753 citations

Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis

1977 • 1,286 citations

Reduced angiogenesis and tumor progression in gelatinase A-deficient mice.

1998 • 887 citations

Quantitative Zymography: Detection of Picogram Quantities of Gelatinases

1994 • 866 citations

In vitro rapid organization of endothelial cells into capillary-like networks is promoted by collagen matrices.

1983 • 616 citations

Growth of microvessels in serum-free matrix culture of rat aorta. A quantitative assay of angiogenesis in vitro.

1990 • 599 citations

Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells

1992 • 530 citations

Matrix Metalloproteinase Inhibition as a Novel Anticancer Strategy: A Review with Special Focus on Batimastat and Marimastat

1997 • 403 citations

Microscopic observations on the growth of blood capillaries in the living mammal

1939 • 372 citations

Tissue inhibitor of metalloproteinases‐2 inhibits bFGF‐induced human microvascular endothelial cell proliferation

1993 • 362 citations

Three-dimensional Type I Collagen Lattices Induce Coordinate Expression of Matrix Metalloproteinases MT1-MMP and MMP-2 in Microvascular Endothelial Cells

1998 • 358 citations

Membrane and matrix localization of proteinases: a common theme in tumor cell invasion and angiogenesis

1988 • 354 citations

The role of matrix metalloproteases and their inhibitors in tumour invasion, metastasis and angiogenesis

1994 • 333 citations

Suppression of apoptosis by basement membrane requires three-dimensional tissue organization and withdrawal from the cell cycle.

1996 • 333 citations

Vascular endothelial growth factor, platelet-derived growth factor, and insulin-like growth factor-1 promote rat aortic angiogenesis in vitro.

1994 • 297 citations

Type IV collagenase(s) and TIMPs modulate endothelial cell morphogenesis in vitro

1993 • 296 citations

Microvessel count and cerebrospinal fluid basic fibroblast growth factor in children with brain tumours

1994 • 234 citations

Integrins, angiogenesis and vascular cell survival

1996 • 190 citations

Fibronectin promotes the elongation of microvessels during angiogenesis in vitro

1993 • 150 citations

Thrombospondin-1 Modulates Angiogenesisin Vitroby Up-Regulation of Matrix Metalloproteinase-9 in Endothelial Cells

1997 • 147 citations

Human Dermal Microvascular Endothelial Cells Produce Matrix Metalloproteinases in Response to Angiogenic Factors and Migration

1995 • 146 citations

Spreading of trypsinized cells: Cytoskeletal dynamics and energy requirements

1990 • 137 citations

Endogenous regulation of angiogenesis in the rat aorta model. Role of vascular endothelial growth factor.

1997 • 137 citations

Cyclic angiogenesis and blood vessel regression in the ovary: blood vessel regression during luteolysis involves endothelial cell detachment and vessel occlusion.

1996 • 136 citations

Angiogenic role of endogenous basic fibroblast growth factor released by rat aorta after injury.

1993 • 120 citations

Paracrine interactions between fibroblasts and endothelial cells in a serum-free coculture model. Modulation of angiogenesis and collagen gel contraction.

1994 • 119 citations

Progression of mycosis fungoides is associated with changes in angiogenesis and expression of the matrix metalloproteinases 2 and 9

1997 • 97 citations

Localization of mRNAs representing collagenase and TIMP in sections of healing human burn wounds.

1993 • 95 citations

The Effect of Luteal “Rescue” on the Expression and Localization of Matrix Metalloproteinases and Their Tissue Inhibitors in the Human Corpus Luteum

1998 • 91 citations

Inhibition of angiogenesis in vitro by Arg-Gly-Asp-containing synthetic peptide.

1991 • 77 citations

Vascular endothelial growth factor levels in ovarian cyst fluid correlate with malignancy.

1999 • 74 citations

Modulation of Angiogenesis in Vitro by Laminin-Entactin Complex

1994 • 69 citations

Isolation and characterization of vasoformative endothelial cells from the rat aorta

1994 • 58 citations

Matrix Metalloproteinases in Blood Vessel Development in Human Fetal Skin and in Cutaneous Tumors

1995 • 57 citations

Matrix metalloproteinases and endometrial remodelling.

1994 • 53 citations

The Effect of Luteal "Rescue" on the Expression and Localization of Matrix Metalloproteinases and Their Tissue Inhibitors in the Human Corpus Luteum

1998 • 32 citations

60K gelatinase involved in mammary gland involution is regulated by β-oestradiol

1998 • 28 citations

The Rat Aorta Model of Angiogenesis and Its Applications

1996 • 11 citations