The conserved, buried aspartic acid in oxidized Escherichia coli thioredoxin has a pKa of 7.5. Its titration produces a related shift in global stability

The interpretation of protein structures: Estimation of static accessibility

1971 • 5,771 citations

Solvent-Accessible Surfaces of Proteins and Nucleic Acids

1983 • 2,685 citations

AREAS, VOLUMES, PACKING, AND PROTEIN STRUCTURE

1977 • 2,631 citations

[14]Determination and analysis of urea and guanidine hydrochloride denaturation curves

1986 • 2,265 citations

Electrostatic Interactions in Macromolecules: Theory and Applications

1990 • 1,324 citations

Calculating the electrostatic potential of molecules in solution: Method and error assessment

1988 • 1,096 citations

Crystal structure of thioredoxin from Escherichia coli at 1.68 Å resolution

1990 • 568 citations

[16] Nonlinear least-squares analysis

1985 • 449 citations

Three-dimensional structure of Escherichia coli thioredoxin-S2 to 2.8 A resolution.

1975 • 435 citations

Stabilization of protein structure by interaction of α-helix dipole with a charged side chain

1988 • 229 citations

Conformational and functional similarities between glutaredoxin and thioredoxins.

1984 • 205 citations

Thioredoxin and related proteins in procaryotes

1988 • 161 citations

Three-dimensional solution structure of the reduced form of Escherichia coli thioredoxin determined by nuclear magnetic resonance spectroscopy

1990 • 160 citations

Glutaredoxin from calf thymus. Purification to homogeneity.

1982 • 133 citations

Urea dependence of thiol-disulfide equilibria in thioredoxin: confirmation of the linkage relationship and a sensitive assay for structure

1989 • 115 citations

Replacement of proline-76 with alanine eliminates the slowest kinetic phase in thioredoxin folding

1987 • 98 citations

A conformational study of thioredoxin and its tryptic fragments.

1981 • 96 citations

Cloning and nucleotide sequence of the trxA gene of Escherichia coli K-12

1985 • 72 citations

Proton-transfer effects in the active-site region of Escherichia coli thioredoxin using two-dimensional proton NMR

1991 • 64 citations

Equilibrium and kinetic measurements of the conformational transition of reduced thioredoxin

1987 • 56 citations

Escherichia coli thioredoxin folds into two compact forms of different stability to urea denaturation

1989 • 48 citations

Structural differences between oxidized and reduced thioredoxin monitored by two‐dimensional ¹H NMR spectroscopy

1988 • 38 citations

Structural comparison between oxidized and reduced Escherichia coli thioredoxin. Proton NMR and CD studies

1988 • 32 citations

Spectroscopic characterization of thioredoxin covalently modified with monofunctional organoarsenical reagents

1987 • 26 citations

PAP: a protein analysis package

1990 • 9 citations