The postsynaptic density: a possible role in long-lasting effects in the central nervous system.

The neurosciences. Fourth study program

1980 • 1,165 citations

The Biochemistry of Memory: A New and Specific Hypothesis

1984 • 1,048 citations

Isolation and characterization of postsynaptic densities from various brain regions: enrichment of different types of postsynaptic densities.

1980 • 780 citations

Preferential localization of polyribosomes under the base of dendritic spines in granule cells of the dentate gyrus

1982 • 665 citations

Biochemical and immunochemical evidence that the "major postsynaptic density protein" is a subunit of a calmodulin-dependent protein kinase.

1983 • 617 citations

Synapsin I (Protein I), a nerve terminal-specific phosphoprotein. II. Its specific association with synaptic vesicles demonstrated by immunocytochemistry in agarose-embedded synaptosomes.

1983 • 535 citations

The structure of postsynaptic densities isolated from dog cerebral cortex: I. overall morphology and protein composition

1977 • 481 citations

Fodrin: axonally transported polypeptides associated with the internal periphery of many cells.

1981 • 480 citations

Brief bursts of high-frequency stimulation produce two types of structural change in rat hippocampus.

1980 • 474 citations

Long-lasting morphological changes in dendritic spines of dentate granular cells following stimulation of the entorhinal area

1977 • 450 citations

The small pyramidal neuron of the rat cerebral cortex

1969 • 427 citations

The Cell surface and neuronal function

1980 • 379 citations

Neurobiology: Memory and molecular turnover

1984 • 377 citations

The effects of kindling on GABA-Mediated inhibition in the dentate gyrus of the rat. I. Paired-pulse depression

1983 • 333 citations

Subsynaptic Plate Perforations: Changes with Age and Experience in the Rat

1978 • 328 citations

Cytoplasmic actin in neuronal processes as a possible mediator of synaptic plasticity.

1982 • 306 citations

The kindling model of epilepsy: A review

1980 • 287 citations

Synaptic correlates of associative potentiation/depression: an ultrastructural study in the hippocampus

1983 • 278 citations

Swelling of dendritic spines in the fascia dentata after stimulation of the perforant fibers as a mechanism of post-tetanic potentiation

1975 • 275 citations

Synaptic proteins. Characterization of tubulin and actin and identification of a distinct postsynaptic density polypeptide.

1978 • 264 citations

Immunocytochemical localization of calmodulin and a heat-labile calmodulin-binding protein (CaM-BP80) in basal ganglia of mouse brain.

1980 • 256 citations

Actin in erythrocyte ghosts and its association with spectrin. Evidence for a nonfilamentous form of these two molecules in situ.

1975 • 256 citations

Selective association of N-methyl aspartate and quisqualate types of L-glutamate receptor with brain postsynaptic densities.

1984 • 238 citations

Plasticity in the central nervous system: do synapses divide?

1983 • 231 citations

Effects of differential environments on plasticity of dendrites of cortical pyramidal neurons in adult rats

1978 • 222 citations

Identification of the Major Postsynaptic Density Protein as Homologous with the Major Calmodulin‐Binding Subunit of a Calmodulin‐Dependent Protein Kinase

1984 • 220 citations

Brain ankyrin. A membrane-associated protein with binding sites for spectrin, tubulin, and the cytoplasmic domain of the erythrocyte anion channel.

1984 • 215 citations

Presence of calmodulin in postsynaptic densities isolated from canine cerebral cortex.

1979 • 208 citations

The structure of postsynaptic densities isolated from dog cerebral cortex: II. characterization and arrangement of some of the major proteins within the structure

1977 • 204 citations

Subcellular distribution in cerebral cortex of two proteins phosphorylated by a cAMP-dependent protein kinase.

1979 • 200 citations

Quantitative Synaptic Changes With Differential Experience In Rat Brain

1971 • 194 citations

The kindled amygdala model of epilepsy: anticonvulsant action of amino acid antagonists

1983 • 180 citations

Function of a calmodulin in postsynaptic densities. III. Calmodulin-binding proteins of the postsynaptic density.

1981 • 179 citations

Effect of environmental complexity on cortical synapses of rats: Preliminary results

1972 • 168 citations

Tubulin in postsynaptic junctional lattice

1975 • 162 citations

Perforated postsynaptic densities: probable intermediates in synapse turnover.

1982 • 159 citations

Identification of glycoproteins and proteins at synapses in the central nervous system.

1977 • 153 citations

Localization of calmodulin in rat cerebellum by immunoelectron microscopy

1980 • 149 citations

Synaptic remodelling during development and maturation: Junction differentiation and splitting as a mechanism for modifying connectivity

1984 • 142 citations

Immunocytochemical localization, in synapses, of protein I, an endogenous substrate for protein kinases in mammalian brain.

1979 • 135 citations

Function of calmodulin in postsynaptic densities. II. Presence of a calmodulin- activatable protein kinase activity

1981 • 131 citations

Form of the postsynaptic density. A serial section study.

1978 • 127 citations

Morphology and molecular composition of isolated postsynaptic junctional structures

1978 • 122 citations

Alterations in polyribosomes associated with dendritic spines during the reinnervation of the dentate gyrus of the adult rat

1983 • 121 citations

Long-Term Potentiation in the Hippocampal Slice: Evidence for Stimulated Secretion of Newly Synthesized Proteins

1981 • 118 citations

Spine Stems on Tectal Interneurons in Jewel Fish Are Shortened by Social Stimulation

1978 • 117 citations

The effects of kindling on GABA-mediated inhibition in the dentate gyrus of the rat. II. Receptor binding

1983 • 116 citations

Rapid dendritic spine stem shortening during one-trial learning: The honeybee's first orientation flight

1982 • 115 citations

Cytoskeletal organization at the postsynaptic complex.

1981 • 115 citations

Biological Membranes: The Dynamics of their Organization

1972 • 114 citations

Neurotransmitter and neuromodulator function in the kindled seizure and state

1982 • 110 citations

Increase in postsynaptic density material in optic target neurons of the rat suprachiasmatic nucleus after bilateral enucleation

1980 • 96 citations

Experimental Approaches to Understanding the Role of Protein Phosphorylation in the Regulation of Neuronal Function

1983 • 92 citations

Effect of anisomycin on stimulation-induced changes in dendritic spines of the dentate granule cells

1982 • 91 citations

Fine structure of synapses in the cerebral cortex

1963 • 90 citations

Morphological changes in pyramidal cells of mammalian neocortex associated with increased use

1974 • 86 citations

Kindling alters the calcium/calmodulin-dependent phosphorylation of synaptic plasma membrane proteins in rat hippocampus.

1984 • 84 citations

Polyribosomes at the Base of Dendritic Spines of Central Nervous System Neurons--Their Possible Role in Synapse Construction and Modification

1983 • 80 citations

Na+-independent binding of GABA to the triton X-100 treated synaptic membranes from cerebellum of rat brain

1977 • 78 citations

Protein and glycoprotein composition of synaptic junctions prepared from discrete synaptic regions and different species

1979 • 75 citations

Identification of lectin receptors associated with rat brain postsynaptic densities

1977 • 71 citations

Anticonvulsant action of amino acid antagonists against kindled hippocampal seizures

1984 • 71 citations

Antibodies to the beta-adrenergic receptor: attenuation of catecholamine-sensitive adenylate cyclase and demonstration of postsynaptic receptor localization in brain.

1983 • 70 citations

PROTEIN PHOSPHORYLATION IN SYNAPTIC MEMBRANES REGULATED BY ADENOSINE 3′:5′‐MONOPHOSPHATE: REGIONAL AND SUBCELLULAR DISTRIBUTION OF THE ENDOGENOUS SUBSTRATES

1979 • 69 citations

Neurochemical correlates of the kindling model of epilepsy

1982 • 69 citations

Changes in synaptic membrane phosphorylation after tetanic stimulation in the dentate area of the rat hippocampal slice

1980 • 68 citations

Cyclic AMP-stimulated protein kinases at brain synaptic junctions.

1979 • 67 citations

Synapses and Synaptosomes

1976 • 62 citations

Phosphoproteins in Postsynaptic Densities

1982 • 60 citations

Role of neurotransmitters in seizure mechanisms in the kindling model of epilepsy.

1984 • 56 citations

Synaptic contact curvature: effects of differential rearing on rat occipital cortex

1982 • 55 citations

Identification of a protein related to tubulin in the postsynaptic density.

1977 • 53 citations

Effect of inhibitors of protein synthesis on the development of kindled seizures in rats

1979 • 51 citations

Pharmacological investigation of gamma-aminobutyric acid (gaba) and fully-developed generalized seizures in the amygdala-kindled rat

1982 • 49 citations

Social experience affects the development of dendritic spines and branches on tectal interneurons in the jewel fish

1979 • 47 citations

Postmortem Accumulation of Tubulin in Postsynaptic Density Preparations

1982 • 47 citations

Function of calmodulin in postsynaptic densities. I. Presence of a calmodulin-activatable cyclic nucleotide phosphodiesterase activity.

1981 • 46 citations

Synaptic changes in frog brain after stimulation with potassium chloride

1975 • 42 citations

?-Aminobutyric acid receptors in brain postsynaptic densities

1981 • 42 citations

Plasticity in synaptic appositions of optic nerve afferents under different lighting conditions

1979 • 42 citations

Evidence that a Cerebellum‐Enriched, Synaptic Junction Glycoprotein Is Related to Fodrin and Resists Extraction with Triton in a Calcium‐Dependent Manner

1984 • 38 citations

Differential Solubilization of γ‐Aminobutyric Acid Receptive Sites from Membranes of Mammalian Brain

1981 • 34 citations

Biologic activity in a fragment of recombinant human interferon alpha.

1984 • 27 citations

Enlargement of Spinal Cord Synapses after Repetitive Stimulation of a Single Posterior Root

1969 • 26 citations

Histophysiology of synapses and neurosecretion

1965 • 23 citations

A lasting change in protein phosphorylation associated with septal kindling

1982 • 23 citations

Characterization of Na⁺‐Independent GABA and Flunitrazepam Binding Sites in Preparations of Synaptic Membranes and Postsynaptic Densities Isolated from Canine Cerebral Cortex and Cerebellum

1984 • 21 citations

FACTORS INFLUENCING THE PROTEIN METABOLISM OF THE BRAIN

1965 • 20 citations

Plasticity of dendritic spine formation: A state dependent stochastic process

1981 • 18 citations

The Synapses of the Nervous System

1979 • 11 citations

Fine structure of synapses of the central nervous system in resinless sections.

1983 • 5 citations