Characterisation of the metal‐ion–GDP complex at the active sites of transforming and nontransforming p21 proteins by observation of the ¹⁷O‐Mn superhyperfine coupling and by kinetic methods

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Electron paramagnetic resonance of transition ions

1970 • 9,043 citations

Biochemical Properties of Hormone-Sensitive Adenylate Cyclase

1980 • 1,016 citations

NUCLEOSIDE PHOSPHOROTHIOATES

1985 • 830 citations

Comparative biochemical properties of normal and activated human ras p21 protein

1984 • 713 citations

Structure of the GDP Domain of EF-Tu and Location of the Amino Acids Homologous to ras Oncogene Proteins

1985 • 626 citations

Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules.

1984 • 607 citations

Viral oncogenes

1985 • 605 citations

The role of guanosine 5′-triphosphate in polypeptide chain elongation

1978 • 559 citations

The product of ras is a GTPase and the T24 oncogenic mutant is deficient in this activity

1984 • 539 citations

Biological and biochemical properties of human rasH genes mutated at codon 61

1986 • 538 citations

Homologies Between Signal Transducing G Proteins and ras Gene Products

1984 • 500 citations

Predicted nucleotide-binding properties of p21 protein and its cancer-associated variant

1983 • 390 citations

Expression of p21 proteins in Escherichia coli and stereochemistry of the nucleotide-binding site.

1986 • 287 citations

Mutant ras-encoded proteins with altered nucleotide binding exert dominant biological effects.

1986 • 285 citations

The magnesium ion-dependent adenosine triphosphatase of myosin. Two-step processes of adenosine triphosphate association and adenosine diphosphate dissociation

1974 • 261 citations

Metal Ions in Biological Systems

1985 • 258 citations

A Model for the Tertiary Structure of p21, the Product of the ras Oncogene

1985 • 248 citations

Ha-ras proteins exhibit GTPase activity: point mutations that activate Ha-ras gene products result in decreased GTPase activity.

1985 • 195 citations

Yeast and mammalian ras proteins have conserved biochemical properties

1985 • 195 citations

Absolute configuration of the diastereomers of adenosine 5'-O-(1-thiotriphosphate): consequences for the stereochemistry of polymerization by DNA-dependent RNA polymerase from Escherichia coli.

1978 • 164 citations

Activation of ras genes in human tumors does not affect localization, modification, or nucleotide binding properties of p21

1984 • 144 citations

Factors Involved in the Transfer of Aminoacyl-tRNA to the Ribosome

1977 • 142 citations

Homology between human bladder carcinoma oncogene product and mitochondrial ATP-synthase

1983 • 131 citations

Ras p21 proteins with high or low GTPase activity can efficiently transform NIH3T3 cells

1986 • 118 citations

Biochemical properties of normal and oncogenic ras p21

1985 • 114 citations

Homologies in the primary structure of GTP-binding proteins: the nucleotide-binding site of EF-Tu and p21.

1984 • 109 citations

Modification of Elongation‐Factor‐Tu · Guanine‐Nucleotide Interaction by Kirromycin

1978 • 106 citations

Studies on the Polypeptide Elongation Factors from E. coli

1974 • 103 citations

Purification and Characterization of Human H-ras Proteins Expressed in Escherichia coli

1985 • 101 citations

Identification of the six ligands to manganese(II) in transition-state-analog complexes of creatine kinase: oxygen-17 superhyperfine coupling from selectively labeled ligands

1980 • 75 citations

Exchange of ADP, ATP and 1:N⁶‐Ethenoadenosine 5′‐Triphosphate at G‐Actin

1979 • 73 citations

Guanosine nucleotide binding by highly purified Ha-ras-encoded p21 protein produced in Escherichia coli.

1984 • 71 citations

Hydrolysis of GTP by elongation factor Tu can be induced by monovalent cations in the absence of other effectors.

1982 • 71 citations

Viral Harvey ras p21 expressed in Escherichia coli purifies as a binary one-to-one complex with GDP.

1985 • 67 citations

Biochemical Properties of a Highly Purified v-ras^H p21 Protein Overproduced in Escherichia coli and Inhibition of Its Activities by a Monoclonal Antibody

1985 • 65 citations

Purification and characterization of human H-ras proteins expressed in Escherichia coli.

1985 • 53 citations

Biochemical characterization of polypeptides encoded by mutated human Ha-ras1 genes.

1986 • 42 citations

Biological Magnetic Resonance

1984 • 37 citations

Stereochemistry of the elongation factor Tu . GTP complex

1983 • 35 citations

Biochemical properties of a highly purified v-rasH p21 protein overproduced in Escherichia coli and inhibition of its activities by a monoclonal antibody.

1985 • 32 citations

The Structure of the EF‐Tu · GDP · Me²⁺ Complex

1982 • 30 citations

Structural Investigations of the Mg · ATP Complex at the Active Site of Porcine Adenylate Kinase Using Phosphorothioate Analogs and Electron Paramagnetic Resonance of Mn(II) with Chiral ¹⁷)‐Labelled ATP Analogs

1983 • 20 citations

Electron-paramagnetic-resonance studies of manganese(II) complexes with elongation factor Tu from Bacillus stearothermophilus. Observation of a GTP hydrolysis intermediate state complex

1984 • 18 citations

31P-NMR spectra of the Ha-ras p21. Nucleotide complexes

1986 • 17 citations

The preparation of thiophosphate analogs of GDP and their interaction with EF‐Tu

1979 • 13 citations

The Binding of Nucleotides and Metal Ions to Elongation Factor Tu fromBacillus stearothermophilus as Studied by Equilibrium Dialysis

1981 • 7 citations

THE INFLUENCE OF METAL ION COMPLEXATION ON³¹P-NMR PARAMETERS OF PHOSPHOROTHIOATES OF GUANOSINE NUCLEOTIDES

1984 • 5 citations