Stereoselective Interaction of Mianserin with 5-HT3 Receptors

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1973 • 12,522 citations

Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves.

1978 • 2,400 citations

Multiple serotonin receptors: differential binding of [3H]5-hydroxytryptamine, [3H]lysergic acid diethylamide and [3H]spiroperidol.

1979 • 1,321 citations

Identification of serotonin M-receptor subtypes and their specific blockade by a new class of drugs

1985 • 845 citations

The binding of serotonergic ligands to the porcine choroid plexus: Characterization of a new type of serotonin recognition site

1984 • 598 citations

Pharmacological properties of GR38032F, a novel antagonist at 5‐HT₃ receptors

1988 • 378 citations

The potential anxiolytic activity of GR38032F, a 5‐HT₃‐receptor antagonist

1988 • 332 citations

Pharmacological characterization of 5‐hydroxytryptamine‐induced depolarization of the rat isolated vagus nerve

1987 • 276 citations

Identification of serotonin 5-HT3 recognition sites in membranes of N1E-115 neuroblastoma cells by radioligand binding.

1988 • 149 citations

[3H]-BRL 43694 (granisetron), a specific ligand for 5-HT3 binding sites in rat brain cortical membranes

1989 • 138 citations

The pharmacological characterization of 5‐HT₃ receptors in three isolated preparations derived from guinea‐pig tissues

1990 • 110 citations

Identification of Multiple Binding Sites for [³H]5‐Hydroxytryptamine in the Rat CNS

1986 • 75 citations

5-HT1C receptor antagonists have anxiolytic-like actions in the rat social interaction model

1992 • 69 citations

Evidence that the 5‐HT₃ receptors of the rat, mouse and guinea‐pig superior cervical ganglion may be different

1991 • 69 citations

Stereoselective blockade of central [3H]5-hydroxytryptamine binding to multiple sites (5-HT1A, 5-HT1B and 5-HT1C) by mianserin and propranolol

1987 • 50 citations

Characterisation of 5-HT3 recognition sites in membranes of NG 108-15 neuroblastoma-glioma cells with [3H]ICS 205-930

1988 • 49 citations

Mianserin in the treatment of depressive illness and anxiety states in general practice.

1978 • 40 citations

Presynaptic α-block and inhibition of noradrenaline and 5-hydroxytryptamine reuptake by a series of compounds related to mianserin

1981 • 30 citations

Antidepressant interactions with 5-hydroxytryptamine3 receptor binding sites

1989 • 28 citations