Pharmacological properties of GR38032F, a novel antagonist at 5‐HT₃ receptors

SOME QUANTITATIVE USES OF DRUG ANTAGONISTS

1959 • 3,948 citations

Proposals for the classification and nomenclature of functional receptors for 5-hydroxytryptamine

1986 • 1,255 citations

Identification of serotonin M-receptor subtypes and their specific blockade by a new class of drugs

1985 • 845 citations

TWO KINDS OF TRYPTAMINE RECEPTOR

1957 • 838 citations

pA, A NEW SCALE FOR THE MEASUREMENT OF DRUG ANTAGONISM

1947 • 759 citations

MDL 72222: a potent and highly selective antagonist at neuronal 5-hydroxytryptamine receptors

1984 • 437 citations

The rat anococcygeus muscle and its response to nerve stimulation and to some drugs

1972 • 365 citations

The potential anxiolytic activity of GR38032F, a 5‐HT₃‐receptor antagonist

1988 • 332 citations

Pharmacological characterization of 5‐hydroxytryptamine‐induced depolarization of the rat isolated vagus nerve

1987 • 276 citations

STIMULANT ACTIONS OF VOLATILE ANAESTHETICS ON SMOOTH MUSCLE

1964 • 261 citations

Pharmacological Experiments on Isolated Preparations

1971 • 243 citations

RECEPTORS FOR 5‐HYDROXYTRYPTAMINE AND NORADRENALINE IN RABBIT ISOLATED EAR ARTERY AND AORTA

1976 • 198 citations

Study of the contractile effect of 5-hydroxytryptamine (5-HT) in the isolated longitudinal muscle strip from guinea-pig ileum

1985 • 194 citations

MECHANISM OF THE INDIRECT SYMPATHOMIMETIC EFFECT OF 5‐HYDROXYTRYPTAMINE ON THE ISOLATED HEART OF THE RABBIT

1976 • 151 citations

Blockade of neuronal tryptamine receptors by metoclopramide

1978 • 148 citations

EVIDENCE FOR TWO TYPES OF EXCITATORY RECEPTOR FOR 5‐HYDROXYTRYPTAMINE IN DOG ISOLATED VASCULATURE

1980 • 136 citations

Effect of the 5-HT3 receptor antagonist, GR38032F, on responses to injection of a neurokinin agonist into the ventral tegmental area of the rat brain

1987 • 113 citations

Increased gut cholinergic activity and antagonism of 5‐hydroxytryptamine M‐receptors by BRL 24924: potential clinical importance of BRL 24924

1987 • 113 citations

An analysis of the uptake of 5-hydroxytryptamine by the myenteric plexus of the small intestine of the guinea pig.

1971 • 97 citations

The depolarizing action of 5‐hydroxytryptamine on rabbit vagal afferent and sympathetic neurones in vitro and its selective blockade by ICS 205–930

1986 • 96 citations

THE EFFECTS OF α‐ADRENOCEPTOR AGONISTS AND ANTAGONISTS ON RESPONSES OF TRANSMURALLY STIMULATED PROSTATIC AND EPIDIDYMAL PORTIONS OF THE ISOLATED VAS DEFERENS OF THE RAT

1979 • 93 citations

5-hydroxytryptamine-induced relaxation of isolated mammalian smooth muscle

1983 • 91 citations

The effect of GR38032F, novel 5‐HT₃‐receptor antagonist on gastric emptying in the guinea‐pig

1987 • 74 citations

PHARMACOLOGICAL EVIDENCE FOR THE SUBCLASSIFICATION OF CENTRAL DOPAMINE RECEPTORS IN THE RAT

1982 • 53 citations

The depolarizing action of 5-hydroxytryptamine on rabbit vagal primary afferent and sympathetic neurones and its selective blockade by MDL 72222

1985 • 48 citations

Influence of 5‐hydroxytryptamine uptake on the apparent 5‐hydroxytryptamine antagonist potency of metoclopramide in the rat isolated superior cervical ganglion

1987 • 32 citations

Organ selectivity of drugs Alternatives to receptor selectivity

1982 • 22 citations

Prenalterol is an agonist at β2- as well as at β1-adrenoceptors

1982 • 20 citations

Origin of 5‐hydroxytryptamine‐induced hyperpolarization of the rat superior cervical ganglion and vagus nerve

1987 • 17 citations

Pharmacological interactions between ranitidine, cimetidine, metiamide and tiotidine at histamine H2-receptor sites in guinea-pig atria

1982 • 6 citations