Identification and functional characterization of a novel 27-bp deletion in the macroglycopeptide-coding region of the GPIBA gene resulting in platelet-type von Willebrand disease

Bernard-Soulier Syndrome

1998 • 552 citations

Structures of Glycoprotein Ibα and Its Complex with von Willebrand Factor A1 Domain

2002 • 550 citations

Cloning of the alpha chain of human platelet glycoprotein Ib: a transmembrane protein with homology to leucine-rich alpha 2-glycoprotein.

1987 • 376 citations

The Vascular Biology of the Glycoprotein Ib-IX-V Complex

2001 • 281 citations

Pseudo-von Willebrand's Disease

1982 • 219 citations

Molecular mechanisms of platelet adhesion and activation

1997 • 201 citations

Glycoprotein Ib–IX–V

2003 • 200 citations

Crystal Structure of the Wild-type von Willebrand Factor A1-Glycoprotein Ibα Complex Reveals Conformation Differences with a Complex Bearing von Willebrand Disease Mutations

2004 • 192 citations

Efficient plasma membrane expression of a functional platelet glycoprotein Ib-IX complex requires the presence of its three subunits.

1992 • 191 citations

Mocarhagin, a Novel Cobra Venom Metalloproteinase, Cleaves the Platelet von Willebrand Factor Receptor Glycoprotein Ibα. Identification of the Sulfated Tyrosine/Anionic Sequence Tyr-276−Glu-282 of Glycoprotein Ibα as a Binding Site for von Willebrand Factor and α-Thrombin

1996 • 185 citations

Crystal Structure of the Platelet Glycoprotein Ibα N-terminal Domain Reveals an Unmasking Mechanism for Receptor Activation

2002 • 168 citations

Ristocetin-dependent reconstitution of binding of von Willebrand factor to purified human platelet membrane glycoprotein Ib-IX complex

1988 • 157 citations

Mutation in the gene encoding the alpha chain of platelet glycoprotein Ib in platelet-type von Willebrand disease.

1991 • 155 citations

Polymorphism of human glycoprotein Ib alpha results from a variable number of tandem repeats of a 13-amino acid sequence in the mucin-like macroglycopeptide region. Structure/function implications.

1992 • 148 citations

Pseudo-von Willebrand disease: a mutation in the platelet glycoprotein Ib alpha gene associated with a hyperactive surface receptor

1993 • 118 citations

von Willebrand factor binds to platelets and induces aggregation in platelet-type but not type IIB von Willebrand disease.

1983 • 103 citations

Tyrosine Sulfation of the Glycoprotein Ib-IX Complex: Identification of Sulfated Residues and Effect on Ligand Binding

1994 • 101 citations

Structure and function of the glycoprotein Ib-IX-V complex

1997 • 95 citations

Isolation and functional characterization of the von Willebrand factor-binding domain located between residues His1-Arg293 of the alpha-chain of glycoprotein Ib.

1988 • 94 citations

Platelet-type von Willebrand Disease

1996 • 69 citations

The role of O-linked protein glycosylation in beta-cell dysfunction.

2002 • 63 citations

Polymorphysm of human glycoprotein Ibα results from a variable number of tandem repeats of a 13-amino acid sequence in the mucin-like macroglycopeptide region

1992 • 58 citations

Substitution of Val for Met at residue 239 of platelet glycoprotein Ib alpha in Japanese patients with platelet-type von Willebrand disease

1995 • 55 citations

Identification of a novel point mutation in platelet glycoprotein Ibα, Gly to Ser at residue 233, in a Japanese family with platelet-type von Willebrand disease

2003 • 44 citations

Expression of the phenotypic abnormality of platelet-type von Willebrand disease in a recombinant glycoprotein Ib alpha fragment.

1993 • 40 citations

Cloning of the Murine Platelet Glycoprotein Ibα Gene Highlighting Species-Specific Platelet Adhesion

1997 • 40 citations

Expression and Functional Characterization of an Abnormal Platelet Membrane Glycoprotein Ibα (Met239 → Val) Reported in Patients With Platelet-Type von Willebrand Disease

1997 • 37 citations

Cytoplasmic Truncation of Glycoprotein Ibα Weakens Its Interaction with von Willebrand Factor and Impairs Cell Adhesion

2003 • 28 citations

Functional analysis of the C-terminal flanking sequence of platelet glycoprotein Ibα using canine–human chimeras

2002 • 27 citations

A Single Glycosylation Site Within the Receptor-Binding Domain of the Avian Sarcoma/Leukosis Virus Glycoprotein Is Critical for Receptor Binding

2002 • 26 citations

The mucin-like macroglycopeptide region of glycoprotein Ibalpha is required for cell adhesion to immobilized von Willebrand factor (VWF) under flow but not for static VWF binding.

2002 • 24 citations

De novo mutation of the platelet glycoprotein Ib?? gene in a patient with pseudo-von Willebrand disease

1997 • 24 citations

The Mucin-like Macroglycopeptide Region of Glycoprotein Ibα is Required for Cell Adhesion to Immobilized von Willebrand Factor (VWF) Under Flow but not for Static VWF Binding

2002 • 22 citations

Structural determinants within platelet glycoprotein Ibα involved in its binding to von Willebrand factor

2000 • 21 citations

Unmasking a new recognition signal for O-linked glycosylation in the chorionic gonadotropin β subunit

2002 • 9 citations