Spontaneous Production of Interleukin-6 by Alveolar Macrophages from Human Immunodeficiency Virus Type 1-Infected Patients

Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

1986 • 2,137 citations

Interleukin-6: An Overview

1990 • 1,910 citations

Abnormalities of B-Cell Activation and Immunoregulation in Patients with the Acquired Immunodeficiency Syndrome

1983 • 1,625 citations

Biology of multifunctional cytokines: IL 6 and related molecules (IL 1 and TNF)

1990 • 1,307 citations

Production of hybridoma growth factor by human monocytes

1987 • 1,133 citations

Biological and clinical aspects of interleukin 6

1990 • 1,091 citations

Classification System for Human T-Lymphotropic Virus Type III/ Lymphadenopathy-Associated Virus Infections

1986 • 690 citations

Purification to homogeneity and characterization of human B-cell differentiation factor (BCDF or BSFp-2).

1985 • 679 citations

Infection with HIV is associated with elevated IL-6 levels and production.

1990 • 594 citations

Molecular Regulation of B Lymphocyte Response

1988 • 579 citations

Interleukin 6 induces human immunodeficiency virus expression in infected monocytic cells alone and in synergy with tumor necrosis factor alpha by transcriptional and post-transcriptional mechanisms.

1990 • 529 citations

Structure and expression of cDNA and genes for human interferon-beta-2, a distinct species inducible by growth-stimulatory cytokines.

1986 • 505 citations

Bacterial lipopolysaccharide and inflammatory mediators augment IL-6 secretion by human endothelial cells.

1989 • 470 citations

Immunologic Abnormalities in the Acquired Immunodeficiency Syndrome

1985 • 380 citations

Two interferon mRNAs in human fibroblasts: in vitro translation and Escherichia coli cloning studies.

1980 • 341 citations

Endotoxemia elicits increased circulating beta 2-IFN/IL-6 in man.

1989 • 323 citations

Induction of IL-6 (B cell stimulatory factor-2/IFN-beta 2) production by HIV.

1989 • 314 citations

AIDS — An Immunologic Reevaluation

1984 • 286 citations

Pulmonary Infectious Complications of Human Immunodeficiency Virus Infection: Part I

1990 • 285 citations

Human immunodeficiency virus type 1 (HIV-1) infection of the central nervous system: an evaluation of cytokines in cerebrospinal fluid

1989 • 259 citations

Human keratinocytes and monocytes release factors which regulate the synthesis of major acute phase plasma proteins in hepatic cells from man, rat, and mouse.

1984 • 225 citations

Infection with the human immunodeficiency virus (HIV) is associated with an in vivo increase in B lymphocyte activation and immaturity.

1987 • 219 citations

Macrophages and the human immunodeficiency virus

1990 • 169 citations

Endotoxin-induced cytokine gene expression in vivo. III. IL-6 mRNA and serum protein expression and the in vivo hematologic effects of IL-6.

1991 • 154 citations

Human endothelial culture supernatant (HECS): a growth factor for hybridomas.

1980 • 149 citations

Regulation of the acute phase and immune responses in viral disease. Enhanced expression of the beta 2-interferon/hepatocyte-stimulating factor/interleukin 6 gene in virus-infected human fibroblasts.

1988 • 131 citations

B-cell activation and HIV-1 infection: Deeds and misdeeds

1990 • 120 citations

Quantitative analysis of serum IL-6 and its correlation with increased levels of serum IL-2R in HIV-induced diseases.

1990 • 108 citations

Human immunodeficiency virus does not induce interleukin-1, interleukin-6, or tumor necrosis factor in mononuclear cells

1990 • 98 citations

Production of Cytokines by Peripheral Blood Monocytes/Macrophages Infected with Human Immunodeficiency Virus Type I (HIV-I)

1990 • 98 citations

Bronchoalveolar Lavage Cells and Proteins in Patients with the Acquired Immunodeficiency Syndrome

1985 • 92 citations

Mechanisms accounting for lymphocytic alveolitis in hypersensitivity pneumonitis.

1990 • 84 citations

The Synergism of Aecessory Cells and of Soluble a‐Factors Derived from Them in the Activation of B Cells to Proliferation

1984 • 78 citations

B cell activation during HIV-1 infection. II. Cell-to-cell interactions and cytokine requirement.

1991 • 77 citations

Human Alveolar Macrophage and Blood Monocyte Interleukin-6 Production

1990 • 74 citations

Phenotypical and Functional Analysis of Bronchoalveolar Lavage Lymphocytes in Patients with HIV Infection

1988 • 64 citations

Frequent Identification of HIV-1 DNA in Bronchoalveolar Lavage Cells Obtained from Individuals with the Acquired Immunodeficiency Syndrome

1991 • 56 citations

Alveolar Macrophages from Patients with AIDS and AIDS-related Complex Constitutively Synthesize and Release Tumor Necrosis Factor Alpha

1991 • 50 citations

Detection of HIV-1 in human lung macrophages using the polymerase chain reaction

1990 • 49 citations

Pulmonary alveolar macrophages from patients with active sarcoidosis express type IV collagenolytic proteinase. An enzymatic mechanism for influx of mononuclear phagocytes at sites of disease activity.

1989 • 37 citations

Human Retroviruses and Lung Involvement

1989 • 29 citations

Purification and NH2-terminal Amino-acid-sequence of a New T-cell Derived Lymphokine With Growth-factor Activity for B-cell Hybridomas

1987 • 22 citations