Sporadic Heterozygous Frameshift Mutation ofHESX1Causing Pituitary and Optic Nerve Hypoplasia and Combined Pituitary Hormone Deficiency in a Japanese Patient

Slipped-strand mispairing: a major mechanism for DNA sequence evolution.

1987 • 2,272 citations

Cloning and characterization of a novel bicoid-related homeobox transcription factor gene, RIEG, involved in Rieger syndrome

1996 • 881 citations

Mutations in the homeobox gene HESX1/Hesx1 associated with septo-optic dysplasia in human and mouse

1998 • 769 citations

The nuclear receptor steroidogenic factor 1 acts at multiple levels of the reproductive axis.

1994 • 600 citations

Mutations in PROP1 cause familial combined pituitary hormone deficiency

1998 • 560 citations

A Pituitary Cell-Restricted T Box Factor, Tpit, Activates POMC Transcription in Cooperation with Pitx Homeoproteins

2001 • 533 citations

Mutation of the POU-Specific Domain of Pit-1 and Hypopituitarism Without Pituitary Hypoplasia

1992 • 451 citations

Ptx1, a bicoid-related homeo box transcription factor involved in transcription of the pro-opiomelanocortin gene.

1996 • 419 citations

Mutations in LHX3 result in a new syndrome revealed by combined pituitary hormone deficiency

2000 • 364 citations

Reciprocal Interactions of Pit1 and GATA2 Mediate Signaling Gradient–Induced Determination of Pituitary Cell Types

1999 • 319 citations

Heterozygous HESX1 mutations associated with isolated congenital pituitary hypoplasia and septo-optic dysplasia

2001 • 315 citations

In situ hybridization analysis of anterior pituitary hormone gene expression during fetal mouse development.

1994 • 314 citations

Rpx: a novel anterior-restricted homeobox gene progressively activated in the prechordal plate, anterior neural plate and Rathke’s pouch of the mouse embryo

1996 • 286 citations

NeuroD1/β2 Contributes to Cell-Specific Transcription of the Proopiomelanocortin Gene

1997 • 230 citations

The fate map of the cephalic neural primordium at the presomitic to the 3-somite stage in the avian embryo

1988 • 211 citations

Anterior pituitary development: Short tales from dwarf mice

1992 • 208 citations

Heritable Disorders of Pituitary Development1

1999 • 174 citations

How many homeobox genes does it take to make a pituitary gland?

1998 • 161 citations

Early steps in pituitary organogenesis

1999 • 153 citations

Molecular effects of novel mutations inHesx1/HESX1associated with human pituitary disorders

2001 • 136 citations

Sequence, Genomic Organization, and Expression of the Novel Homeobox Gene Hesx1

1995 • 113 citations

Hormonal, metabolic, and neuroradiologic abnormalities associated with septo-optic dysplasia

1984 • 85 citations

The Endocrine Spectrum of Septo-optic Dysplasia

1984 • 83 citations

Heritable Disorders of Pituitary Development

1999 • 81 citations

Evidence for possible Mendelian inheritance of septo‐optic dysplasia

1996 • 60 citations

Truncation at the C-terminus of the DAX-1 protein impairs its biological actions in patients with X-linked adrenal hypoplasia congenita.

1996 • 60 citations

Linear Growth Characteristics of Congenitally GH-Deficient Infants from Birth to One Year of Age

2001 • 38 citations

Truncation at the C-terminus of the DAX-1 protein impairs its biological actions in patients with X-linked adrenal hypoplasia congenita

1996 • 31 citations

Linear Growth Characteristics of Congenitally GH-Deficient Infants from Birth to One Year of Age

2001 • 19 citations