Quantitation of inhibitory G-proteins in fat cells of obese and normal-weight human subjects

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Metabolism of Isolated Fat Cells

1964 • 4,431 citations

A general, fast, and sensitive micromethod for DNA determination: Application to rat and mouse liver, rat hepatoma, human leukocytes, chicken fibroblasts, and yeast cells

1981 • 246 citations

Modification of the rat adipocyte A1 adenosine receptor-adenylate cyclase system during chronic exposure to an A1 adenosine receptor agonist: alterations in the quantity of GS alpha and Gi alpha are not associated with changes in their mRNAs.

1989 • 120 citations

Expression and purification of functional G protein alpha subunits using a baculovirus expression system.

1992 • 85 citations

Guanine-nucleotide-binding proteins expressed in rat white adipose tissue. Identification of both mRNAs and proteins corresponding to Gi1, Gi2 and Gi3

1989 • 83 citations

Fat cell adenylate cyclase system. Enhanced inhibition by adenosine and GTP in the hypothyroid rat.

1985 • 80 citations

Gi down-regulation as a mechanism for heterologous desensitization in adipocytes.

1992 • 72 citations

Chemically induced hypothyroidism produces elevated amounts of the α subunit of the inhibitory guanine nucleotide binding protein (Gi) and the β subunit common to all G-proteins

1987 • 65 citations

Adenosine, thyroid status and regulation of lipolysis

1979 • 58 citations

Attenuated adenosine-sensitivity and decreased adenosine-receptor number in adipocyte plasma membranes in human obesity

1991 • 56 citations

Alterations in mRNA levels, expression, and function of GTP-binding regulatory proteins in adipocytes from obese mice (C57BL/6J-ob/ob)

1991 • 53 citations

Adipocyte plasma membranes contain two G_i subtypes but are devoid of G_o

1988 • 52 citations

Effect of adrenaline infusion on fatty acid and glucose turnover in lean and obese human subjects in the post-absorptive and fed states

1991 • 51 citations

Short-term hyperthyroidism modulates adenosine receptors and catalytic activity of adenylate cyclase in adipocytes

1987 • 49 citations

Quantification of the α and β subunits of the transducing elements (Gs and Gi) of adenylate cyclase in adipocyte membranes from lean and obese (ob/ob) mice

1990 • 33 citations

Attenuated adenosine R-site effect in adipocytes in obesity

1986 • 28 citations

A1 adenosine receptors in the human fat cell: tissue distribution and regulation of radioligand binding

1991 • 28 citations

Guanine-nucleotide-binding proteins Gi and Gs in fat-cells from normal, hypothyroid and obese human subjects

1989 • 27 citations

Abundance of the α-subunits of Gi1, Gi2 and Go in synaptosomal membranes from several regions of the rat brain is increased in hypothyroidism

1991 • 23 citations

Prostaglandin E2 action and binding in human adipocytes: Effects of sex, age, and obesity

1988 • 20 citations

Effect of obesity on circulating intermediary metabolite concentrations in the absence of impaired glucose tolerance.

1991 • 15 citations

Regulation of adenylate cyclase in plasma membranes of human intraabdominal and abdominal subcutaneous adipocytes

1993 • 14 citations

Thyroid status and adenosine content of adipose tissue

1987 • 14 citations