PMP22 Accumulation in Aggresomes: Implications for CMT1A Pathology

Aggresomes: A Cellular Response to Misfolded Proteins

1998 • 2,116 citations

UBIQUITIN-DEPENDENT PROTEIN DEGRADATION

1996 • 1,680 citations

Inhibition of Proteasome Activities and Subunit-Specific Amino-Terminal Threonine Modification by Lactacystin

1995 • 1,601 citations

trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor

1991 • 830 citations

DNA deletion associated with hereditary neuropathy with liability to pressure palsies

1993 • 791 citations

The Receptor for Ciliary Neurotrophic Factor

1991 • 604 citations

Translocation and clustering of endosomes and lysosomes depends on microtubules.

1987 • 498 citations

The gene for the peripheral myelin protein PMP–22 is a candidate for Charcot–Marie–Tooth disease type 1A

1992 • 497 citations

Intracellular turnover of cystic fibrosis transmembrane conductance regulator. Inefficient processing and rapid degradation of wild-type and mutant proteins.

1994 • 482 citations

Ubiquitin, cellular inclusions and their role in neurodegeneration

1998 • 396 citations

Two autosomal dominant neuropathies result from reciprocal DNA duplication/deletion of a region on chromosome 17

1994 • 313 citations

Peripheral myelin protein–22 gene maps in the duplication in chromosome 17p11.2 associated with Charcot–Marie–Tooth 1A

1992 • 295 citations

Altered Trafficking of Mutant Connexin32

1997 • 211 citations

Retroviral-mediated gene transfer of the peripheral myelin protein PMP22 in Schwann cells: modulation of cell growth.

1995 • 181 citations

Cytoskeletal proteins and Golgi dynamics

1998 • 180 citations

Biology and Genetics of Hereditary Motor and Sensory Neuropathies

1995 • 179 citations

Apoptotic phenotype induced by overexpression of wild-type gas3/PMP22: its relation to the demyelinating peripheral neuropathy CMT1A.

1995 • 177 citations

Peripheral Myelin Protein 22 and Protein Zero: a Novel Association in Peripheral Nervous System Myelin

1999 • 160 citations

Neurons Promote the Translocation of Peripheral Myelin Protein 22 into Myelin

1997 • 148 citations

The endosomal-lysosomal system of neurons: new roles

1995 • 136 citations

Cell-specific cyclic AMP-mediated induction of the PDGF receptor.

1990 • 134 citations

Ultrastructural PMP22 expression in inherited demyelinating neuropathies

1996 • 131 citations

Many facets of the peripheral myelin protein PMP22 in myelination and disease

1998 • 124 citations

Transport ofTrembler-JMutant Peripheral Myelin Protein 22 Is Blocked in the Intermediate Compartment and Affects the Transport of the Wild-Type Protein by Direct Interaction

1999 • 123 citations

Impaired Intracellular Trafficking Is a Common Disease Mechanism ofPMP22Point Mutations in Peripheral Neuropathies

1999 • 121 citations

Upregulation of the Endosomal-Lysosomal Pathway in the Trembler-J Neuropathy

1997 • 111 citations

Aberrant Protein Trafficking inTremblerSuggests a Disease Mechanism for Hereditary Human Peripheral Neuropathies

1997 • 109 citations

Production and characterization of monoclonal antibodies to the extracellular domain of P0

1993 • 107 citations

Temporal expression pattern of peripheral myelin protein 22 during in vivo and in vitro myelination

1999 • 87 citations

Dominant-negative effect on adhesion by myelin Po protein truncated in its cytoplasmic domain.

1996 • 83 citations

Underexpression of messenger RNA for peripheral myelin protein 22 in hereditary neuropathy with liability to pressure palsies

1997 • 57 citations

Influence of elevated expression of rat wild-type PMP22 and its mutant PMP22 Trembler on cell growth of NIH3T3 fibroblasts

1997 • 57 citations

Myelin Po protein mutated at Cys21 has a dominant-negative effect on adhesion of wild type Po

1998 • 32 citations

Experimental models of peripheral neuropathies.

1999 • 30 citations

Activation of the autophagy, c-FOS and ubiquitin expression, and nucleolar alterations in Schwann cells precede demyelination in tellurium-induced neuropathy

1999 • 25 citations

Long duration electroporation for achieving high level expression of glucocorticoid receptors in mammalian cell lines

1999 • 18 citations