Interferon activity and its characterization in the sera of patients with head and neck cancer

Isolation of mononuclear cells and granulocytes from human blood.

1968 • 9,672 citations

PLAQUE FORMATION AND ISOLATION OF PURE LINES WITH POLIOMYELITIS VIRUSES

1954 • 3,832 citations

Probit Analysis: A Statistical Treatment of the Sigmoid Response Curve.

1947 • 1,144 citations

Immune Interferon in the Circulation of Patients with Autoimmune Disease

1979 • 907 citations

Enhanced NK cell activity in mice injected with interferon and interferon inducers

1978 • 735 citations

Probit Analysis: A Statistical Treatment of the Sigmoid Response Curve.

1952 • 657 citations

Natural Killer Cells: Characteristics and Regulation of Activity

1979 • 582 citations

Augmentation by interferon of human natural and antibody-dependent cell-mediated cytotoxicity

1979 • 532 citations

Leukocyte Interferon-Induced Tumor Regression in Human Metastatic Breast Cancer, Multiple Myeloma, and Malignant Lymphoma

1980 • 503 citations

K562—A human erythroleukemic cell line

1979 • 463 citations

Binding of Sheep Red Blood Cells to a Large Population of Human Lymphocytes

1971 • 462 citations

Systemic Lupus Erythematosus: Presence in Human Serum of an Unusual Acid-Labile Leukocyte Interferon

1982 • 460 citations

Circulating Immune Complexes in the Serum in Systemic Lupus Erythematosus and in Carriers of Hepatitis B Antigen QUANTITATION BY BINDING TO RADIOLABELED Clq

1974 • 436 citations

PRIMARY SEX-RATIO AND SIZE OF FAMILY

1970 • 366 citations

On the varied biologic effects of interferon

1977 • 353 citations

Preliminary Observations on the Effect of Human Leukocyte Interferon in Non-Hodgkin's Lymphoma

1978 • 267 citations

The Serum Levels and Urinary Excretion of β₂-Microglobulin in Apparently Healthy Subjects

1972 • 259 citations

Radioimmunoassay of β₂-Microglobulin in Human Biological Fluids

1971 • 256 citations

Human serum lyses RNA tumour viruses

1975 • 222 citations

Enhanced expression of β ₂ -microglobulin and HLA antigens on human lymphoid cells by interferon

1978 • 215 citations

The Nature of Immune Complexes in Human Cancer Sera

1977 • 204 citations

Age-Related Changes in the Subsets and Functions of Human T Lymphocytes

1978 • 184 citations

T-cell deficiency in patients with squamous cell cancer of the head and neck

1975 • 177 citations

Interferon nomenclature

1980 • 157 citations

Interferon and spontaneous cytotoxicity in man. I. Enhancement of the spontaneous cytotoxicity of peripheral lymphocytes by human leukocyte interferon

1978 • 151 citations

Immune complexes in sera and synovial fluids of patients with rheumatoid arthritis. Radioimmunoassay with monocylonal rheumatoid factor.

1975 • 148 citations

Inhibition by interferon of delayed-type hypersensitivity in the mouse.

1975 • 125 citations

Interferon Preparations as Modifiers of Immune Responses

1972 • 125 citations

Natural cell‐mediated cytotoxicity in rats. III. Effects of immunopharmacologic treatments on natural reactivity and on reactivity augmented by polyinosinic‐polycytidylic acid

1978 • 125 citations

Interferons and their actions

1977 • 122 citations

Antibodies to alpha-interferon in a patient with systemic lupus erythematosus.

1982 • 121 citations

Interferon acts directly on human B lymphocytes to modulate immunoglobulin synthesis.

1981 • 114 citations

Suppression of Mouse Antibody Producing Spleen Cells by Various Interferon Preparations

1973 • 109 citations

Immunologic abnormalities in head and neck cancer

1974 • 105 citations

Suppressive Effect of Interferon on the Humoral Immune Response to Sheep Red Blood Cells in Mice

1974 • 95 citations

Inactivation and lysis of oncornaviruses by human serum

1976 • 95 citations

Complement receptor binding of C3b-coated cells treated with C3b inactivator, beta 1H globulin and trypsin.

1979 • 90 citations

Delayed hypersensitivity reactions in patients with squamous cell cancer of the head and neck

1974 • 84 citations

Gamma (immune) interferon production by leukocytes from a patient with a TG cell proliferative disease

1982 • 81 citations

Interferon Therapy in Hodgkin's Disease

1976 • 79 citations

Detection of gamma interferon in the sera of patients with Behçet's disease

1982 • 66 citations

Host Cell Modification of Lymphocytic Choriomeningitis Virus and Newcastle Disease Virus Altering Viral Inactivation by Human Complement

1977 • 63 citations

Depressed natural killer cell activity in patients with hepatocellular carcinoma in vitro effects of interferon and levamisole

1982 • 63 citations

Identification of the T cell subset that produces human gamma interferon.

1982 • 62 citations

Thymus-derived lymphocytes in patients with solid malignancies

1975 • 58 citations

alpha-Interferon increases immunoglobulin production in cultured human mononuclear leukocytes.

1983 • 53 citations

A Plaque Technique for Assay and Characterization of Antibody‐Dependent Cytotoxic Effector (K) Cells

1975 • 53 citations

Complement Receptor Binding of C3b-Coated Cells Treated with C3b Inactivator, β1H Globulin and Trypsin

1979 • 52 citations

Interferon Therapy for Neoplastic Diseases in Man In Vitro and In Vivo Studies

1978 • 49 citations

Depressed natural killer cell activity in patients with hepatocellular carcinoma in vitro effects of interferon and levamisole

1982 • 49 citations

A simplified isotope release assay for cell-mediated cytotoxicity against anchorage dependent target cells

1977 • 44 citations

Interferon inhibits the generation of allospecific suppressor T lymphocytes.

1982 • 44 citations

SYSTEMIC AND IN SITU NATURAL KILLER ACTIVITY IN TUMOR-BEARING MICE AND PATIENTS WITH CANCER

1980 • 42 citations

Basis for the Probit Analysis of an Interferon Plaque Reduction Assay

1972 • 40 citations

Production of Interferon by Immune Lymphocytes Exposed to Herpes Simplex Virus-Antibody Complexes

1975 • 35 citations

Immunologic evaluation of patients with advanced head and neck cancer receiving weekly chemoimmunotherapy

1979 • 35 citations

THE ROLE OF INTERFERON IN IMMEDIATE HYPERSENSITIVITY AND AUTOIMMUNE DISEASES

1980 • 35 citations

Subpopulations of human lymphocytes defined by 2 -microglobulin.

1973 • 34 citations

Standing Waves on the Moon

1969 • 33 citations

Major Immunoglobulin Ratios in Carcinoma of the Head and Neck

1978 • 27 citations

Modulation of the human in vitro antibody response by human leukocyte interferon preparations

1981 • 26 citations

Evaluation of effects of interferon and interferon inducers on the immune response

1977 • 24 citations

A Plaque Technique for Assay and Characterization of Antibody-Dependent Cytotoxic Effector (K) Cells

1975 • 23 citations

Factors which influence inactivation of vesicular stomatitis virus by fresh human serum

1978 • 21 citations

NATURAL KILLER CELLS IN TUMOUR-BEARING PATIENTS11Support for this work was received from the Ontario Cancer Treatment and Research Foundation (HFP) and the Medical Research Council of Canada (MGB).

1980 • 17 citations

Immunobiology in Otolaryngology

1978 • 12 citations

Peripheral k-lymphocyte population in head and neck cancer

1984 • 9 citations

Antibodies Against Nicotinic Acetylcholine Receptor and Skeletal Muscle in Human and Experimental Myasthenia Gravis

1975 • 8 citations

Interferon (type-? and ?) production by fresh and cryopreserved human mononuclear cells

1981 • 6 citations