Exporting calcium from cells

Ion motive ATPases. I. Ubiquity, properties, and significance to cell function

1987 • 964 citations

Molecular Cloning and Functional Expression of the Cardiac Sarcolemmal Na ⁺ -Ca ²⁺ Exchanger

1990 • 751 citations

Cleavage of the Plasma Membrane Na+/Ca2+ Exchanger in Excitotoxicity

2005 • 532 citations

Generation, Control, and Processing of Cellular Calcium Signals

2001 • 516 citations

Calcium pump of the plasma membrane is localized in caveolae.

1993 • 419 citations

Tissue specificity and alternative splicing of the Na+/Ca2+ exchanger isoforms NCX1, NCX2, and NCX3 in rat

1997 • 409 citations

Biogenesis: Plasma membrane calcium ATPase: 15 years of work on the purified enzyme ¹

1994 • 403 citations

Acidic phospholipids, unsaturated fatty acids, and limited proteolysis mimic the effect of calmodulin on the purified erythrocyte Ca2+ - ATPase.

1981 • 388 citations

Extrusion of calcium from rod outer segments is driven by both sodium and potassium gradients

1989 • 374 citations

Cloning of the NCX2 isoform of the plasma membrane Na(+)-Ca2+ exchanger

1994 • 353 citations

Cloning of a Third Mammalian Na+-Ca2+ Exchanger, NCX3

1996 • 347 citations

Targeted Ablation of Plasma Membrane Ca2+-ATPase (PMCA) 1 and 4 Indicates a Major Housekeeping Function for PMCA1 and a Critical Role in Hyperactivated Sperm Motility and Male Fertility for PMCA4

2004 • 326 citations

Balance and Hearing Deficits in Mice with a Null Mutation in the Gene Encoding Plasma Membrane Ca2+-ATPase Isoform 2

1998 • 299 citations

Pharmacology of Brain Na⁺/Ca²⁺Exchanger: From Molecular Biology to Therapeutic Perspectives

2004 • 297 citations

Initial localization of regulatory regions of the cardiac sarcolemmal Na(+)-Ca2+ exchanger.

1993 • 290 citations

Identification of a peptide inhibitor of the cardiac sarcolemmal Na(+)-Ca2+ exchanger.

1991 • 277 citations

Mutations in a plasma membrane Ca2+-ATPase gene cause deafness in deafwaddler mice

1998 • 274 citations

Plasma Membrane Ca2+ ATPase 4 Is Required for Sperm Motility and Male Fertility

2004 • 257 citations

Tissue-specific expression of Na(+)-Ca2+ exchanger isoforms.

1994 • 246 citations

Regulation of the cardiac Na(+)-Ca2+ exchanger by Ca2+. Mutational analysis of the Ca(2+)-binding domain.

1995 • 239 citations

Mutually exclusive and cassette exons underlie alternatively spliced isoforms of the Na/Ca exchanger.

1994 • 235 citations

Charge movement during Na+ translocation by native and cloned cardiac Na+/Ca2+ exchanger

1991 • 221 citations

Functional comparison of the three isoforms of the Na⁺/Ca²⁺ exchanger (NCX1, NCX2, NCX3)

1998 • 219 citations

Targeted Disruption of Na+/Ca2+ Exchanger Gene Leads to Cardiomyocyte Apoptosis and Defects in Heartbeat

2000 • 203 citations

Primary structure and functional expression of the Na/Ca,K-exchanger from bovine rod photoreceptors.

1992 • 203 citations

A New Topological Model of the Cardiac Sarcolemmal Na+-Ca2+ Exchanger

1999 • 196 citations

Identification of the high affinity Ca(2+)-binding domain of the cardiac Na(+)-Ca2+ exchanger.

1994 • 193 citations

NMR Solution Structure of a Complex of Calmodulin with a Binding Peptide of the Ca²⁺ Pump^,

1999 • 192 citations

Regulation of the Cardiac Na+-Ca2+ Exchanger by the Endogenous XIP Region

1997 • 175 citations

Na+-Ca2+ exchange in bovine rod outer segments requires and transports K+

1989 • 172 citations

Plasma Membrane Ca2+-ATPase Isoforms 2b and 4b Interact Promiscuously and Selectively with Members of the Membrane-associated Guanylate Kinase Family of PDZ (PSD95/Dlg/ZO-1) Domain-containing Proteins

2001 • 158 citations

Molecular Cloning of a Third Member of the Potassium-dependent Sodium-Calcium Exchanger Gene Family,NCKX3

2001 • 157 citations

Plasma Membrane Ca2+ ATPase Isoform 4b Binds to Membrane-associated Guanylate Kinase (MAGUK) Proteins via Their PDZ (PSD-95/Dlg/ZO-1) Domains

1998 • 155 citations

The plasmamembrane calmodulin–dependent calcium pump

2001 • 154 citations

Charge movements during the Na+-Ca2+ exchange in heart sarcolemmal vesicles.

1980 • 145 citations

The Product of HUM1, a Novel Yeast Gene, Is Required for Vacuolar Ca²⁺/H⁺ Exchange and Is Related to Mammalian Na⁺/Ca²⁺ Exchangers

1996 • 143 citations

Null Mutation in the Gene Encoding Plasma Membrane Ca2+-ATPase Isoform 2 Impairs Calcium Transport into Milk

2004 • 139 citations

Primary structure of the cAMP-dependent phosphorylation site of the plasma membrane calcium pump

1989 • 138 citations

Molecular Cloning of a Novel Potassium-dependent Sodium-Calcium Exchanger from Rat Brain

1998 • 124 citations

Analysis of the tissue-specific distribution of mRNAs encoding the plasma membrane calcium-pumping ATPases and characterization of an alternately spliced form of PMCA4 at the cDNA and genomic levels.

1992 • 121 citations

Cloning and expression of isoform 2 of the human plasma membrane Ca2+ ATPase. Functional properties of the enzyme and its splicing products

1994 • 115 citations

Molecular Cloning of a Sixth Member of the K+-dependent Na+/Ca2+ Exchanger Gene Family, NCKX6

2004 • 115 citations

Effects of PMCA and SERCA pump overexpression on the kinetics of cell Ca2+ signalling

2000 • 113 citations

Alternative Splicing of the First Intracellular Loop of Plasma Membrane Ca2+-ATPase Isoform 2 Alters Its Membrane Targeting

2003 • 109 citations

Interaction of the Plasma Membrane Ca2+ Pump 4b/CI with the Ca2+/Calmodulin-dependent Membrane-associated Kinase CASK

2003 • 106 citations

The Expression of Plasma Membrane Ca2+ Pump Isoforms in Cerebellar Granule Neurons Is Modulated by Ca2+

1999 • 106 citations

A Point Mutation in a Plasma Membrane Ca2+-ATPase Gene Causes Deafness in Wriggle Mouse Sagami

1999 • 104 citations

A Comparative Functional Analysis of Plasma Membrane Ca2+ Pump Isoforms in Intact Cells

2003 • 101 citations

Plasma Membrane Ca2+ ATPase Isoform 2b Interacts Preferentially with Na+/H+ Exchanger Regulatory Factor 2 in Apical Plasma Membranes

2002 • 99 citations

Calcineurin Controls the Transcription of Na+/Ca2+ Exchanger Isoforms in Developing Cerebellar Neurons

2000 • 90 citations

NAADP⁺initiates the Ca²⁺response during fertilization of starfish oocytes

2001 • 88 citations

Molecular Cloning of a Fourth Member of the Potassium-dependent Sodium-Calcium Exchanger Gene Family, NCKX4

2002 • 85 citations

Deficiency in plasma membrane calcium ATPase isoform 2 increases susceptibility to noise-induced hearing loss in mice

2002 • 83 citations

Characterization of PISP, a Novel Single‐PDZ Protein That Binds to All Plasma Membrane Ca²⁺‐ATPase b‐Splice Variants

2003 • 66 citations

Calcineurin Controls the Expression of Isoform 4CII of the Plasma Membrane Ca2+ Pump in Neurons

2000 • 64 citations

Alternative promoters and cardiac muscle cell-specific expression of the Na⁺/Ca²⁺exchanger gene

1998 • 51 citations

Molecular Studies of the Cardiac Sarcolemmal Sodium‐Calcium Exchanger

1991 • 50 citations

The Ca2+ pumps and the Na+/Ca2+ exchangers.

1998 • 47 citations

Plasma Membrane Ca2+-ATPase Associates with the Cytoskeleton in Activated Platelets through a PDZ-binding Domain

2001 • 38 citations

Cloning of the Multipartite Promoter of the Sodium-Calcium Exchanger Gene NCX1 and Characterization of Its Activity in Vascular Smooth Muscle Cells

1998 • 35 citations

Protein Kinase C Phosphorylates Plasma Membrane Ca2+Pump Isoform 4a at Its Calmodulin Binding Domain

1999 • 34 citations

The sodium-calcium exchanger of bovine rod photoreceptors: K+-dependence of the purified and reconstituted protein

1991 • 33 citations

A novel plasma membrane Ca2+-pump inhibitor: caloxin 1A1

2005 • 24 citations

Forefront of Na+/Ca2+ Exchanger Studies: Role of Na+/Ca2+ Exchanger – Lessons From Knockout Mice

2004 • 18 citations

Alternatively Spliced Isoforms of the Na+/Ca2+Exchanger in the Guinea Pig Cochlea

1997 • 17 citations

Multiple Functional States of the Cardiac Na⁺‐Ca²⁺ Exchanger

1996 • 16 citations

The N‐terminal portion of the main cytosolic loop mediates K⁺ sensitivity in the retinal rod Na⁺/Ca²⁺‐K⁺‐exchanger

2000 • 7 citations