Biological activity and metabolism of 20‐hydroxyeicosatetraenoic acid in the human platelet

A Protein Binding Assay for Adenosine 3′:5′-Cyclic Monophosphate

1970 • 3,269 citations

Leukotrienes and Lipoxins: Structures, Biosynthesis, and Biological Effects

1987 • 2,237 citations

Prostaglandin Endoperoxides. Novel Transformations of Arachidonic Acid in Human Platelets

1974 • 1,410 citations

Enzyme immunoassays of eicosanoids using acetylcholine esterase as label: an alternative to radioimmunoassay

1985 • 716 citations

Prostaglandin endoperoxide synthase: structure and catalysis

1991 • 607 citations

On the Mechanism of the Biosynthesis of Prostaglandins E1 and F1α

1967 • 403 citations

The role of lipids in platelet function: with particular reference to the arachidonic acid pathway.

1978 • 364 citations

A Ca2+-insensitive form of fura-2 associated with polymorphonuclear leukocytes. Assessment and accurate Ca2+ measurement.

1987 • 317 citations

Renal cytochrome P450-related arachidonate metabolite inhibits (Na+ + K+)ATPase

1985 • 314 citations

Cytochrome P-450 Metabolism of Arachidonic Acid

1991 • 290 citations

Transcellular metabolism of neutrophil-derived leukotriene A4 by human platelets. A potential cellular source of leukotriene C4.

1988 • 278 citations

Cytochrome P-450 metabolism of arachidonic acid: formation and biological actions of "epoxygenase"-derived eicosanoids.

1988 • 261 citations

Effect of Cytochrome P450 Arachidonate Metabolites on Ion Transport in Rabbit Kidney Loop of Henle

1991 • 216 citations

Regulation of arachidonate metabolism via lipoxygenase and cyclo-oxygenase by 12-HPETE, the product of human platelet lipoxygenase

1979 • 208 citations

Arachidonic acid metabolism in rabbit renal cortex. Formation of two novel dihydroxyeicosatrienoic acids.

1981 • 164 citations

Metabolism of 20-hydroxyeicosatetraenoic acid by cyclooxygenase

1989 • 164 citations

Regulation of arachidonate-induced platelet aggregation by the lipoxygenase product, 12-hydroperoxyeicosatetraenoic acid

1982 • 155 citations

12S,20-dihydroxyicosatetraenoic acid: a new icosanoid synthesized by neutrophils from 12S-hydroxyicosatetraenoic acid produced by thrombin- or collagen-stimulated platelets.

1984 • 139 citations

Vasoactivity of 20-hydroxyeicosatetraenoic acid is dependent on metabolism by cyclooxygenase.

1989 • 129 citations

Metabolism of arachidonate through NADPH-dependent oxygenase of renal cortex.

1981 • 129 citations

Preparation of pentafluorobenzyl esters of arachidonic acid lipoxygenase metabolites

1984 • 120 citations

Structural identification of cytochrome P450-dependent arachidonate metabolites formed by rabbit medullary thick ascending limb cells

1991 • 111 citations

Biosynthesis of prostaglandins.

1972 • 109 citations

Lipoxygenation activity of purified prostaglandin-forming cyclooxygenase

1978 • 95 citations

[43] Cytochrome P-450 arachidonate oxygenase

1990 • 92 citations

Characterization of 11-HETE and 15-HETE, together with prostacyclin, as major products of the cyclooxygenase pathway in cultured rat aorta smooth muscle cells.

1983 • 85 citations

Cytochrome P-450 arachidonate metabolites in rat kidney: characterization and hemodynamic responses

1990 • 83 citations

Autooxidation of docosahexaenoic acid: analysis of ten isomers of hydroxydocosahexaenoate.

1984 • 83 citations

Regulation of arachidonic acid metabolism by cytochrome P-450 in rabbit kidney

1986 • 82 citations

Renal cytochrome P-450-dependent metabolism of arachidonic acid in spontaneously hypertensive rats

1988 • 79 citations

Modulation of erythropoiesis by novel human bone marrow cytochrome P450- dependent metabolites of arachidonic acid

1991 • 46 citations

Human platelet activation in the absence of aggregation: a calcium- dependent phenomenon independent of thromboxane formation

1982 • 42 citations

12-hydroperoxyeicosatetraenoic acid inhibits main platelet functions by activation of soluble guanylate cyclase.

1991 • 36 citations

The ω‐hydroxylation of arachidonic acid by human polymorphonuclear leukocytes

1988 • 21 citations

[11] Quantitation of sulfidopeptide leukotrienes in biological fluids by gas chromatography-mass spectrometry

1990 • 15 citations

Metabolism of prostaglandins, prostaglandin analogs and thromboxane B2 by lung and liver microsomes from pregnant rabbits

1979 • 12 citations

14, 15-cis-episulfide-eicosatrienoic acid, an 'epoxygenase' eicosanoid analog, inhibits ionophore- but not thrombin-induced platelet aggregation.

1991 • 4 citations

Identification of an unusual cyclooxygenase metabolite of arachidonic acid in rabbit renal medulla

1984 • 2 citations