Autooxidation of docosahexaenoic acid: analysis of ten isomers of hydroxydocosahexaenoate.

[53] Lipoxygenase from soybeans

1981 • 919 citations

Prostaglandins, Aspirin-like Drugs and Analgesia

1972 • 871 citations

Docosahexaenoic acid is a strong inhibitor of prostaglandin but not leukotriene biosynthesis.

1983 • 414 citations

Autoxidation of methyl linoleate. Separation and analysis of isomeric mixtures of methyl linoleate hydroperoxides and methyl hydroxylinoleates

1977 • 356 citations

Formation of leukotrienes and other hydroxy acids during platelet-neutrophil interactions in vitro

1982 • 308 citations

The enzymic conversion of all‐cis 8,11,14‐eicosatrienoic acid into prostaglandin E₁

1966 • 307 citations

Oxygenation of Unsaturated Fatty Acids by the Vesicular Gland of Sheep

1967 • 279 citations

Gas chromatographic—mass spectrometric studies of long chain hydroxy acids.—III.¹ The mass spectra of the methyl esters trimethylsilyl ethers of aliphatic hydroxy acids. A facile method of double bond location

1968 • 260 citations

Oxygenation of arachidonic acid by hepatic monooxygenases. Isolation and metabolism of four epoxide intermediates.

1982 • 251 citations

The Molecular basis of neuropathology

1981 • 217 citations

Preparation and purification of lipid hydroperoxides from arachidonic and γ‐linolenic acids

1976 • 216 citations

Determination of double bond position in monounsaturated fatty acid esters by mass spectrometry of their trimethylsilyloxy derivatives

1968 • 216 citations

Regulation of arachidonate metabolism via lipoxygenase and cyclo-oxygenase by 12-HPETE, the product of human platelet lipoxygenase

1979 • 208 citations

Separation and quantitation of free fatty acids and fatty acid methyl esters by reverse phase high pressure liquid chromatography

1983 • 206 citations

Positional specificity of a reticulocyte lipoxygenase. Conversion of arachidonic acid to 15-S-hydroperoxy-eicosatetraenoic acid.

1982 • 202 citations

Chemical and enzymic syntheses of 5-HPETE, a key biological precursor of slow-reacting substance of anaphylaxis (SRS), and 5-HETE

1980 • 196 citations

Arachidonic acid 15-lipoxygenase products from human eosinophils.

1982 • 193 citations

Monohydroxyeicosatetraenoic acids (HETEs) induce degranulation of human neutrophils.

1980 • 186 citations

Preparation and assay of monohydroxy-eicosatetraenoic acids

1980 • 173 citations

Preparation and purification of arachidonic acid hydroperoxides of biological importance

1979 • 161 citations

Cytochrome P-450-dependent oxygenation of arachidonic acid to hydroxyicosatetraenoic acids.

1982 • 147 citations

Synthesis of hydroxy fatty acids from 4, 7, 10, 13, 16, 19-[1-14C] docosahexaenoic acid by human platelets.

1983 • 142 citations

The autoxidation of arachidonic acid: Formation of the proposed SRS-A intermediate

1979 • 140 citations

The regulation of human eosinophil function by endogenous mono-hydroxy-eicosatetraenoic acids (HETEs).

1980 • 138 citations

On the mechanism of the oxygenation of arachidonic acid by human platelet lipoxygenase

1980 • 128 citations

Lipoxygenase Pathway in Islet Endocrine Cells. OXIDATIVE METABOLISM OF ARACHIDONIC ACID PROMOTES INSULIN RELEASE

1983 • 125 citations

Indomethacin-induced accumulation of diglyceride in activated human platelets. The role of diglyceride lipase.

1980 • 122 citations

The mechanism of the rearrangement of linoleate hydroperoxides

1979 • 116 citations

The production of the arachidonate metabolite HETE in vascular tissue

1979 • 115 citations

Mono- and dihydroxyeicosatetraenoic acids alter calcium homeostasis in rabbit neutrophils.

1981 • 110 citations

On the Organization and Mechanism of Prostaglandin Synthetase

1973 • 107 citations

Lipoxygenation activity of purified prostaglandin-forming cyclooxygenase

1978 • 95 citations

Esterification of an endogenously synthesized lipoxygenase product into granulocyte cellular lipids

1981 • 93 citations

12-L-hydroxy-5,8,10,14-eicosatetraenoic acid, a chemotactic fatty acid, is incorporated into neutrophil phospholipids and triglyceride

1979 • 92 citations

Electron impact-induced rearrangement of trimethylsilyl groups in long chain compounds

1968 • 92 citations

Isolation of a pure isomer of linoleic acid hydroperoxide

1975 • 92 citations

Regulation of leukocyte and platelet lipoxygenases by hydroxyeicosanoids

1982 • 89 citations

Alteration of some long-chain esters during gas-liquid chromatography

1960 • 88 citations

Autoxidation of methyl linolenate: Analysis of methyl hydroxylinolenate isomers by high performance liquid chromatography

1977 • 87 citations

Studies on the mechanism of formation of the 5S,12S-dihydroxy-6,8,10,14(E,Z,E,Z)-icosatetraenoic acid in leukocytes

1982 • 84 citations

Fatty acid structural requirements for leukotriene biosynthesis

1980 • 78 citations

Transformation of arachidonic acid into monohydroxy‐eicosatetraenoic acids by mouse peritoneal macrophages

1981 • 71 citations

Metabolism of linoleic and arachidonic acids in VX2 carcinoma tissue: Identification of monohydroxy octadecadienoic acids and monohydroxy eicosatetraenoic acids

1980 • 64 citations

Neutrophil-aggregating activity of monohydroxyeicosatetraenoic acids.

1981 • 62 citations

Specificity of lipoxygenases

1975 • 55 citations

[62] High-pressure liquid chromatography of underivatized fatty acids, hydroxy acids, and prostanoids having different chain lengths and double-bond positions

1982 • 52 citations

Regional synthesis of monohydroxy eicosanoids by the kidney.

1981 • 52 citations

Characterization of monohydroxylated lipoxygenase metabolites of arachidonic and linoleic acid in rabbit peritoneal tissue

1982 • 48 citations

Quantitative analyses of hydroxystearate isomers from hydroperoxides by high pressure liquid chromatography of autoxidized and photosensitized‐oxidized fatty esters

1980 • 47 citations

Lipoxygenase-like enzyme in bat testis microsomes

1978 • 42 citations

Transformation of arachidonic acid in the rat anterior pituitary

1982 • 33 citations

The effect of free radical derived hydroxyicosatetraenoic acids on hexose transport in the human polymorphonuclear leukocyte

1982 • 15 citations

[31] 12-Hydroxyeicosatetraenoic acid and related compounds

1981 • 13 citations

Preparation, Purification, Characterization and Assay of Hydroxy- and Hydroperoxy Eicosatetraenoic Acids

1980 • 5 citations