Novel Role of Brain Stem Pedunculopontine Tegmental Adenylyl Cyclase in the Regulation of Spontaneous REM Sleep in the Freely Moving Rat

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Central cholinergic pathways in the rat: An overview based on an alternative nomenclature (Ch1–Ch6)

1983 • 2,305 citations

Neuronal NADPH diaphorase is a nitric oxide synthase.

1991 • 1,917 citations

Nitric oxide, a novel neuronal messenger

1992 • 1,864 citations

Nitric oxide synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH diaphorase

1991 • 1,364 citations

G-protein-coupled receptors and signaling networks: emerging paradigms

2001 • 1,005 citations

Calcium Influx via the NMDA Receptor Induces Immediate Early Gene Transcription by a MAP Kinase/ERK-Dependent Mechanism

1996 • 781 citations

Neuronal activities in brain-stem cholinergic nuclei related to tonic activation processes in thalamocortical systems

1990 • 779 citations

Bridging the cleft at GABA synapses in the brain

1994 • 622 citations

Molecular biology of glutamate receptors in the central nervous system and their role in excitotoxicity, oxidative stress and aging

1998 • 575 citations

Pedunculopontine Nucleus Region Deep Brain Stimulation in Parkinson Disease: Surgical Anatomy and Terminology

2016 • 565 citations

GABA receptor mechanisms in the central nervous system

1991 • 555 citations

Pedunculopontine tegmental nucleus of the rat: Cytoarchitecture, cytochemistry, and some extrapyramidal connections of the mesopontine tegmentum

1987 • 537 citations

Regulation of Kainate Receptors by cAMP-Dependent Protein Kinase and Phosphatases

1991 • 404 citations

NADPH-diaphorase: A selective histochemical marker for the cholinergic neurons of the pontine reticular formation

1983 • 367 citations

Neuropharmacology of AMPA and kainate receptors

1998 • 362 citations

Type VIII adenylyl cyclase. A Ca2+/calmodulin-stimulated enzyme expressed in discrete regions of rat brain.

1994 • 360 citations

Unitary characteristics of presumptive cholinergic tegmental neurons during the sleep-waking cycle in freely moving cats

1989 • 358 citations

GABAB Receptors: A New Paradigm in G Protein Signaling

2000 • 275 citations

Avoidance Task Training Potentiates Phasic Pontine-Wave Density in the Rat: A Mechanism for Sleep-Dependent Plasticity

2000 • 271 citations

G-Protein-Coupled Modulation of Presynaptic Calcium Currents and Transmitter Release by a GABA_BReceptor

1998 • 270 citations

Arg3.1/Arc mRNA Induction by Ca²⁺and cAMP Requires Protein Kinase A and Mitogen-Activated Protein Kinase/Extracellular Regulated Kinase Activation

2001 • 257 citations

Single cell activity patterns of pedunculopontine tegmentum neurons across the sleep‐wake cycle in the freely moving rats

2002 • 232 citations

Phosphorylation and Modulation of a Kainate Receptor (GluR6) by cAMP-Dependent Protein Kinase

1993 • 231 citations

GABA_B2 Is Essential for G-Protein Coupling of the GABA_B Receptor Heterodimer

2001 • 211 citations

GABAB receptors

1995 • 208 citations

Excitation of the Brain Stem Pedunculopontine Tegmentum Cholinergic Cells Induces Wakefulness and REM Sleep

1997 • 159 citations

Induction of immediate early genes by Ca2+ influx requires cAMP-dependent protein kinase in PC12 cells.

1991 • 155 citations

Microinjection of glutamate into the pedunculopontine tegmentum induces REM sleep and wakefulness in the rat

2001 • 146 citations

Modulation of inhibitory synaptic transmission in the hippocampus

1994 • 139 citations

Q/R editing of the rat GluR5 and GluR6 kainate receptors in vivo and in vitro: evidence for independent developmental, pathological and cellular regulation

1999 • 127 citations

Neuronal activity in the peribrachial area: Relationship to behavioral state control

1995 • 120 citations

Enhancement of rapid eye movement sleep in the rat by cholinergic and adenosinergic agonists infused into the pontine reticular formation

1998 • 101 citations

Endogenous and exogenous nitric oxide in the pedunculopontine tegmentum induces sleep

1997 • 93 citations

Isozyme-dependent Sensitivity of Adenylyl Cyclases to P-site-mediated Inhibition by Adenine Nucleosides and Nucleoside 3′-Polyphosphates

1997 • 91 citations

Evidence That REM Sleep Is Controlled by the Activation of Brain Stem Pedunculopontine Tegmental Kainate Receptor

2002 • 87 citations

Roles of intracellular cAMP and protein kinase A in the actions of dopamine and neurotensin on midbrain dopamine neurons

1992 • 63 citations

A novel role of pedunculopontine tegmental kainate receptors: a mechanism of rapid eye movement sleep generation in the rat

2002 • 58 citations

Spontaneous REM Sleep Is Modulated By the Activation of the Pedunculopontine Tegmental GABA_B Receptors in the Freely Moving Rat

2004 • 53 citations

Inhibition of Adenylate Cyclase of Catfish and Rat Hepatocyte Membranes BY 9-(Tetrahydro-2-Furyl)Adenine (SQ 22536)

1991 • 51 citations

Metabotropic Glutamate Receptor Activation Modulates Kainate and Serotonin Calcium Response in Astrocytes

1997 • 42 citations

Long‐term enhancement of REM sleep by the pituitary adenylyl cyclase‐activating polypeptide (PACAP) in the pontine reticular formation of the rat

1999 • 40 citations

Adenylyl Cyclase Signal Transduction and Alcohol-Induced Sedation

1997 • 38 citations

Regulation of Rapid Eye Movement Sleep in the Freely Moving Rat: Local Microinjection of Serotonin, Norepinephrine, and Adenosine into the Brainstem

2003 • 37 citations

Pertussis toxin-sensitive G proteins mediate carbachol-induced REM sleep and respiratory depression

1995 • 31 citations

Modulation of reflex and sleep related apnea by pedunculopontine tegmental and intertrigeminal neurons

2004 • 29 citations

cAMP and protein kinase A modulate cholinergic rapid eye movement sleep generation

1997 • 28 citations

Phosphorylation by Cyclic AMP‐Dependent Protein Kinase Modulates Agonist Binding to the D₂ Dopamine Receptor

1991 • 27 citations

Infusion of adenylyl cyclase inhibitor SQ22,536 into the medial pontine reticular formation of rats enhances rapid eye movement sleep

2000 • 25 citations

Development of REM sleep drive and clinical implications

2004 • 22 citations

The developmental decrease in REM sleep

2003 • 20 citations

Desynchronization of carbachol-induced theta-like activities by α-adrenergic agents in guinea pig hippocampal slices

1999 • 18 citations

Respiratory effects of cyclic AMP following injection into the nucleus tractus solitarius of rats

1988 • 16 citations

Involvement of cyclic AMP at the level of the nucleus reticularis pontis caudalis in the acoustic startle response

1995 • 14 citations

Evaluation of cAMP involvement in cannabinoid-induced antinociception

1995 • 14 citations

Kainate receptor-mediated activation of the AP-1 transcription factor complex in cultured rat cerebellar granule cells

2000 • 10 citations

Aggression-altering effects of cyclic AMP

1981 • 9 citations

Deleted Work

1955 • 0 citations