Mutation rate at the hprt locus in human cancer cell lines with specific mismatch repair-gene defects

MUTATIONS OF BACTERIA FROM VIRUS SENSITIVITY TO VIRUS RESISTANCE

1943 • 3,852 citations

Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer

1994 • 2,071 citations

Mutation of a mutL Homolog in Hereditary Colon Cancer

1994 • 1,834 citations

Frameshift Mutations and the Genetic Code

1966 • 1,400 citations

Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair.

1996 • 576 citations

Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N'-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation.

1994 • 506 citations

Mutator phenotype of Werner syndrome is characterized by extensive deletions.

1989 • 417 citations

Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability.

1994 • 332 citations

Identification of mismatch repair genes and their role in the development of cancer

1995 • 319 citations

Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene.

1994 • 222 citations

Requirement of the Yeast MSH3 and MSH6 Genes for MSH2-dependent Genomic Stability

1996 • 187 citations

Binding of Mismatched Microsatellite DNA Sequences by the Human MSH2 Protein

1994 • 166 citations

A hPMS2 Mutant Cell Line Is Defective in Strand-specific Mismatch Repair

1995 • 89 citations

Molecular analysis of mutations in mutator colorectal carcinoma cell lines

1995 • 86 citations

Pitfalls and practice of Luria-Delbrück fluctuation analysis: a review.

1988 • 85 citations

Defective postreplication repair in xeroderma pigmentosum variant fibroblasts.

1990 • 70 citations

In vitro induction, expression and selection of thioguanine-resistant mutants with human T-lymphocytes

1990 • 53 citations

Modeling and measurement of the spontaneous mutation rate in mammalian cells

1995 • 50 citations

Fluctuation analyses of spontaneous mutations to 6-thioguanine resistance in Chinese hamster ovary cells in culture

1981 • 13 citations

A hPMS2 Mutant Cell Line Is Defective in Strand-specific Mismatch Repair

1995 • 5 citations