Comparative properties of schistosomal and filarial dihydrofolate reductases

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The gel-filtration behaviour of proteins related to their molecular weights over a wide range

1965 • 3,062 citations

The Pharmacological Basis of Therapeutics

1971 • 1,765 citations

The Biochemistry of Folic Acid and Related Pteridines.

1970 • 1,033 citations

ENZYMATIC REDUCTION OF FOLIC ACID AND DIHYDROFOLIC ACID TO TETRAHYDROFOLIC ACID

1957 • 416 citations

Specific Binding of 4-Amino Folic Acid Analogues by Folic Acid Reductase

1961 • 389 citations

CARBOHYDRATE METABOLISM OF SCHISTOSOMA MANSONI

1950 • 282 citations

Relation of Folic Acid Reductase to Amethopterin Resistance in Cultured Mammalian Cells

1961 • 210 citations

Increased levels of folic acid reductase as a mechanism of resistance to amethopterin in leukemic cells

1961 • 152 citations

Purification and Properties of Dihydrofolate Reductase from Ehrlich Ascites Carcinoma Cells^*

1965 • 130 citations

Enzymatic Synthesis of Deoxyribonucleotides

1966 • 125 citations

Dihydrofolate Reductase from a Resistant Subline of the L1210 Lymphoma

1967 • 109 citations

Dihydrofolic Reductase from Streptococcus faecalis R

1961 • 101 citations

Studies on Dihydrofolic Reductase

1966 • 89 citations

Increased Level of Dihydrofolic Reductase in Leucocytes of Patients Treated with Amethopterin

1962 • 79 citations

The association of increased dihydrofolate reductase with amethopterin resistance in mouse leukemia.

1962 • 72 citations

Studies on suramin. 9. The action of the drug on some enzymes

1950 • 71 citations

Intestinal Absorption Tests and Biopsy of the Jejunum in Subjects with Heavy Hookworm Infection *

1964 • 53 citations

Ion-Dependent Activation of Dihydrofolate Reductase from L1210 Cells^*

1967 • 50 citations

Dihydrofolate Reductase of Streptococcus faecalis

1966 • 48 citations

Studies on suramin. 8. The action of the drug on enzymes and some other proteins. General considerations

1950 • 45 citations

Comparative Biochemistry of Bacterial and Phage-induced Dihydrofolate Reductases

1965 • 43 citations

PAM 1392 [2,4-diamino-6-(3,4-dichlorobenzylamino) Quinazoline] as a chemotherapeutic agent: Plasmodium berghei, P. cynomolgi, P. knowlesi, and Trypanosoma cruzi

1969 • 43 citations

Antischistosomal Action of Tubercidin administered after Absorption into Red Cells

1971 • 43 citations

Metabolic Patterns of Dirofilaria immitis Microfilariae In vitro

1970 • 40 citations

Dihydrofolate reductases within the genus Trypanosoma

1969 • 37 citations

Antimalarial Activity of 2,4-Diamino-6-[(3,4-Dichlorobenzyl) Nitros-Amino] Quinazoline (CI-679 Base) and CI-679 Acetate

1970 • 36 citations

Studies on folic reductase. 3. The level of enzyme activity and response to methotrexate of transplantable mouse tumors.

1965 • 32 citations

Purification and properties of dihydrofolate reductase of sheep liver

1964 • 32 citations

Quinazoline antifolates as inhibitors of dihydrofolate reductase from human leukemia cells

1970 • 26 citations

Purification and Properties of Mutant and Wild-type Dihydrofolate Reductase from Diplococcus pneumoniae

1966 • 25 citations

Dihydrofolate Reductase from Lactobacillus leichmannii. I. Purification and Characterization^*

1965 • 22 citations

The gel-filtration behaviour of dihydrofolate reductases from culture forms of trypanosomatids

1969 • 22 citations

Presence and properties of dihydrofolate reductases within the genus crithidia

1969 • 20 citations

Dihydrofolate reductase from mouse liver and spleen

1971 • 19 citations

Folic Acid in Axenic Cultures of Neoaplectana

1965 • 19 citations

Levels of dihydrofolate reductase and the formate-activating enzyme activities in guinea pig tissues before and after amethopterin administration

1964 • 18 citations

Recent Progress in Some Aspects of the Physiology of Parasitic Protozoa

1970 • 9 citations

Presence and properties of a dihydrofolate reductase from a parasitic nematode, Nippostrongylus brasiliensis

1970 • 9 citations

Effect of Antimitotic Agents on a Filarial Worm (Litomosoides carinii) In vivo

1967 • 7 citations