Levels of dihydrofolate reductase and the formate-activating enzyme activities in guinea pig tissues before and after amethopterin administration

THE COLORIMETRIC DETERMINATION OF PHOSPHORUS

1925 • 19,115 citations

Chromatography of Proteins. II. Fractionation of Serum Protein on Anion-exchange Cellulose

1956 • 662 citations

Crystalline Dihydropteroylglutamic Acid

1960 • 461 citations

ENZYMATIC REDUCTION OF FOLIC ACID AND DIHYDROFOLIC ACID TO TETRAHYDROFOLIC ACID

1957 • 416 citations

Specific Binding of 4-Amino Folic Acid Analogues by Folic Acid Reductase

1961 • 389 citations

Enzymatic Reduction of Dihydrofolic Acid

1958 • 251 citations

STUDIES ON THE IDENTIFICATION OF A FOLATE COMPOUND OF HUMAN SERUM*

1962 • 233 citations

THE MECHANISM OF ACTION OF THE FOLATE ANTAGONISTS IN MAN.

1963 • 226 citations

Relation of Folic Acid Reductase to Amethopterin Resistance in Cultured Mammalian Cells

1961 • 210 citations

Direct Spectrophotometric Evidence for the Oxidation of Tetrahydrofolate during the Enzymatic Synthesis of Thymidylate

1961 • 209 citations

Increased levels of folic acid reductase as a mechanism of resistance to amethopterin in leukemic cells

1961 • 152 citations

Development of a Semi-Synthetic Diet for Young Guinea Pigs

1953 • 120 citations

Increased Dihydrofolate Reductase Activity as a Possible Basis of Drug Resistance in Leukæmia

1961 • 107 citations

Dihydrofolic Reductase from Streptococcus faecalis R

1961 • 101 citations

THE “INDUCTION” OF DIHYDROFOLIC REDUCTASE ACTIVITY IN LEUKOCYTES AND ERYTHROCYTES OF PATIENTS TREATED WITH AMETHOPTERIN*

1963 • 92 citations

The Role of Dihydrofolic Reductase in the Metabolism of One-Carbon Units^*

1963 • 81 citations

Purification and Properties of the Formate-activating Enzyme from Erythrocytes

1962 • 75 citations

Purification and Properties of Folic Acid Reductase from Chicken Liver

1960 • 73 citations

The Metabolic Effects of 4-Aminopteroylglutamic Acid in the Guinea-Pig

1951 • 58 citations

Dihydrofolic reductase in human leukemic leukocytes

1960 • 56 citations

The distribution of the formate activating enzyme and other enzymes involving tetrahydrofolic acid in animal tissues

1960 • 50 citations

Assay for 4-amino folic acid analogues by inhibition of folic acid reductase.

1962 • 47 citations

Thymidine phosphorylation and deoxyribonucleic acid synthesis in human leukaemic cells

1962 • 44 citations

Biochemical Preparations.

1959 • 41 citations

The relation of folic acid reductase to aminopterin toxicity.

1962 • 36 citations

Dihydrofolic Acid Reductase of Calf Thymus^*

1962 • 35 citations

THE NATURE OF SOME NEW DIETARY FACTORS REQUIRED BY GUINEA PIGS

1945 • 31 citations

The metabolism of formate-C14 by rabbit bone marrow in vitro

1955 • 31 citations

Studies on the folic acid vitamins.III. The duration of the effects of the folic acid antagonists in man

1960 • 24 citations

Pyrimidine Metabolism in Man. II. Studies of Leukemic Cells

1960 • 22 citations