The structure of the C-terminal domain of methionine synthase: presenting S-adenosylmethionine for reductive methylation of B12

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

The CCP4 suite: programs for protein crystallography

1994 • 17,203 citations

Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features

1983 • 14,802 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

The protein data bank: A computer-based archival file for macromolecular structures

1977 • 8,627 citations

Solvent content of protein crystals

1968 • 7,954 citations

The interpretation of protein structures: Estimation of static accessibility

1971 • 5,771 citations

Whole-Genome Random Sequencing and Assembly of Haemophilus influenzae Rd

1995 • 5,571 citations

Protein Structure Comparison by Alignment of Distance Matrices

1993 • 3,989 citations

Solvent-Accessible Surfaces of Proteins and Nucleic Acids

1983 • 2,685 citations

Raster3D Version 2.0. A program for photorealistic molecular graphics

1994 • 2,515 citations

Accurate bond and angle parameters for X-ray protein structure refinement

1991 • 2,467 citations

Crystallographic Computing 6

1993 • 1,992 citations

Improved Fourier coefficients for maps using phases from partial structures with errors

1986 • 1,897 citations

Database of homology‐derived protein structures and the structural meaning of sequence alignment

1991 • 1,641 citations

A new approach to protein fold recognition

1992 • 1,239 citations

Prediction of the occurrence of the ADP-binding βαβ-fold in proteins, using an amino acid sequence fingerprint

1986 • 1,172 citations

Comparison of super-secondary structures in proteins

1973 • 885 citations

Structural Mechanisms for Domain Movements in Proteins

1994 • 741 citations

A fast algorithm for rendering space-filling molecule pictures

1988 • 616 citations

How a Protein Binds B ₁₂ : A 3.0 Å X-Ray Structure of B ₁₂ -Binding Domains of Methionine Synthase

1994 • 502 citations

Structure-guided Analysis Reveals Nine Sequence Motifs Conserved among DNA Amino-methyl-transferases, and Suggests a Catalytic Mechanism for these Enzymes

1995 • 473 citations

Crystal structure of catechol O-methyltransferase

1994 • 426 citations

The crystal structure of Haelll methyltransferase covalently complexed to DNA: An extrahelical cytosine and rearranged base pairing

1995 • 366 citations

Crystal structure of the Hhal DNA methyltransferase complexed with S-adenosyl-l-methionine

1993 • 357 citations

Sequence Analysis of the Genome of the Unicellular Cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence Features in the 1 Mb Region from Map Positions 64% to 92% of the Genome

1995 • 301 citations

Buried waters and internal cavities in monomeric proteins

1994 • 280 citations

Characterization of the cobalamin (vitamin B12) biosynthetic genes of Salmonella typhimurium

1993 • 277 citations

Internal cavities and buried waters in globular proteins

1986 • 268 citations

Sequence of the D-aspartyl/L-isoaspartyl protein methyltransferase from human erythrocytes

1989 • 254 citations

Universal Catalytic Domain Structure of AdoMet-dependent Methyltransferases

1995 • 243 citations

Stabilization of protein structure by interaction of α-helix dipole with a charged side chain

1988 • 229 citations

Inherited disorders of folate transport and metabolism

1995 • 201 citations

Isomorphous replacement and anomalous scattering

2010 • 195 citations

Intramolecular cavities in globular proteins

1994 • 180 citations

Three-dimensional crystal structures of Escherichia coli met repressor with and without corepressor

1989 • 177 citations

Unbiased three-dimensional refinement of heavy-atom parameters by correlation of origin-removed Patterson functions

1983 • 169 citations

Adenosylmethionine-dependent synthesis of the glycyl radical in pyruvate formate-lyase by abstraction of the glycine C-2 pro-S hydrogen atom. Studies of [2H]glycine-substituted enzyme and peptides homologous to the glycine 734 site.

1994 • 169 citations

Three-dimensional structure of the adenine-specific DNA methyltransferase M.Taq I in complex with the cofactor S-adenosylmethionine.

1994 • 168 citations

The 1.85 Å Structure of Vaccinia Protein VP39: A Bifunctional Enzyme That Participates in the Modification of Both mRNA Ends

1996 • 161 citations

Cavities and packing at protein interfaces

1994 • 158 citations

Activation of Methionine Synthetase by a Reduced Triphosphopyridine Nucleotide-dependent Flavoprotein System

1974 • 153 citations

The Free Radical of the Anaerobic Ribonucleotide Reductase from Escherichia coli Is at Glycine 681

1996 • 151 citations

Biotin Synthase: Purification, Characterization as a [2Fe-2S]Cluster Protein, and in vitro Activity of the Escherichia coli bioB Gene Product

1994 • 150 citations

An iron-sulfur center and a free radical in the active anaerobic ribonucleotide reductase of Escherichia coli.

1993 • 147 citations

Mechanism of reductive activation of cobalamin-dependent methionine synthase: an electron paramagnetic resonance spectroelectrochemical study

1990 • 147 citations

Routes of Flavodoxin and Ferredoxin Reduction in Escherichia coli

1982 • 137 citations

TOM: a FRODO subpackage for protein-ligand fitting with interactive energy minimization

1987 • 136 citations

Crystal Structure of S-Adenosylmethionine Synthetase

1996 • 119 citations

Cloning and Sequence Analysis of the Escherichia coli metH Gene Encoding Cobalamin-dependent Methionine Synthase and Isolation of a Tryptic Fragment Containing the Cobalamin-binding Domain

1989 • 114 citations

Strategy for data collection from protein crystals using a multiwire counter area detector diffractometer

1985 • 114 citations

Flavodoxin and Ferredoxm ofEscherichia coli

1971 • 113 citations

Structure and Function of S-Adenosylmethionine Synthetase: Crystal Structures of S-Adenosylmethionine Synthetase with ADP, BrADP, and PP_i at 2.8 Å Resolution^,

1996 • 107 citations

Mechanisms of protein and polypeptide helix initiation

1975 • 107 citations

Mutations in the B₁₂-Binding Region of Methionine Synthase: How the Protein Controls Methylcobalamin Reactivity

1996 • 107 citations

Pyruvate formate-lyase (inactive form) and pyruvate formate-lyase activating enzyme of Escherichia coli: Isolation and structural properties

1984 • 106 citations

Assignment of enzymic function to specific protein regions of cobalamin-dependent methionine synthase from Escherichia coli

1993 • 105 citations

The pKa values of two histidine residues in human haemoglobin, the Bohr effect, and the dipole moments of α-helices

1985 • 105 citations

Participation of Cob(I)alamin in the reaction catalyzed by methionine synthase from Escherichia coli: a steady-state and rapid reaction kinetic analysis

1990 • 105 citations

Flavodoxin Is Required for the Activation of the Anaerobic Ribonucleotide Reductase

1993 • 103 citations

Cobalamin-dependent methionine synthase: the structure of a methylcobalamin-binding fragment and implications for other B12-dependent enzymes

1994 • 99 citations

Enzymatic Synthesis of the Methyl Group of Methionine

1964 • 97 citations

The Anaerobic Escherichia coli Ribonucleotide Reductase

1996 • 94 citations

Cobalamin and the Synthesis of Methionine by Escherichia Coli

1964 • 85 citations

Activation of methionine synthase: Further characterization of the flavoprotein system

1977 • 84 citations

Generation of the Glycyl Radical of the Anaerobic Escherichia coli Ribonucleotide Reductase Requires a Specific Activating Enzyme

1995 • 84 citations

The anaerobic ribonucleoside triphosphate reductase from Escherichia coli requires S-adenosylmethionine as a cofactor.

1990 • 82 citations

Interaction ofEscherichia coliCobalamin-Dependent Methionine Synthase and Its Physiological Partner Flavodoxin: Binding of Flavodoxin Leads to Axial Ligand Dissociation from the Cobalamin Cofactor

1997 • 80 citations

Purification and kinetic mechanism of a mammalian methionine synthase from pig liver.

1994 • 77 citations

Stereochemical analysis of the methyl transfer catalyzed by cobalamin-dependent methionine synthase from Escherichia coli B

1986 • 76 citations

Isolation, cloning, mapping, and nucleotide sequencing of the gene encoding flavodoxin in Escherichia coli

1991 • 68 citations

Molecular properties of pyruvate formate-lyase activating enzyme

1993 • 63 citations

The reductive acetyl coenzyme A pathway: sequence and heterologous expression of active methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase from Clostridium thermoaceticum

1994 • 59 citations

Nitrous Oxide Inactivation of Cobalamin-Dependent Methionine Synthase from Escherichia coli: Characterization of the Damage to the Enzyme and Prosthetic Group

1994 • 51 citations

Atomic size packing defects in proteins

1986 • 38 citations

Electrospray mass spectrometric analysis of the domains of a large enzyme: Observation of the occupied cobalamin-binding domain and redefinition of the carboxyl terminus of methionine synthase

1993 • 35 citations

Nucleotide sequence of the metH gene of Escherichia coli K-12 and comparison with that of Salmonella typhimurium LT2

1990 • 34 citations

Bacteriophage T4 gene 55.9 encodes an activity required for anaerobic ribonucleotide reduction.

1994 • 32 citations

Deleted Work

1955 • 0 citations