Synthesis of Cr(IV)-GSH, Its Identification and Its Free Hydroxyl Radical Generation: A Model Compound for Cr(VI) Carcinogenicity

Genotoxicity of chromium compounds. A review

1990 • 451 citations

Protection against tissue damage in vivo by desferrioxamine: What is its mechanism of action?

1989 • 385 citations

Copper, zinc superoxide dismutase catalyzes hydroxyl radical production from hydrogen peroxide.

1990 • 336 citations

Metabolism of the carcinogen chromate by cellular constituents

2007 • 260 citations

The role of oxidative damage in metal carcinogenicity

1991 • 212 citations

The role of oxidative processes in metal carcinogenesis

1991 • 209 citations

Iron Overload Disorders: Natural History, Pathogenesis, Diagnosis, and Therapy

1983 • 191 citations

On the hydroxyl radical formation in the reaction between hydrogen peroxide and biologically generated chromium(V) species

1990 • 184 citations

Chromium (V) and hydroxyl radical formation during the glutathione reductase-catalyzed reduction of chromium (VI)

1989 • 174 citations

The interaction of chromium with nucleic acids

1983 • 165 citations

Reaction of Cr(VI) with ascorbate and hydrogen peroxide generates hydroxyl radicals and causes DNA damage: role of a Cr(IV)-mediated Fenton-like reaction

1994 • 160 citations

Microsomal reduction of the carcinogen chromate produces chromium(V)

1982 • 159 citations

Induction of the heme oxygenase gene in human skin fibroblasts by hydrogen peroxide and UVA (365 nm) radiation: evidence for the involvement of the hydroxyl radical

1990 • 125 citations

Spin-Label Oximetry

1989 • 122 citations

Is there a role for reactive oxygen species in the mechanism of chromium(VI) carcinogenesis?

1991 • 118 citations

ESR evidence for superoxide, hydroxyl radicals and singlet oxygen produced from hydrogen peroxide and nickel(II) complex of glycylglycyl-L-histidine

1989 • 111 citations

On the mechanism of the chromate reduction by glutathione: ESR evidence for the glutathionyl radical and an isolable Cr(V) intermediate

1988 • 92 citations

Long-lived chromium(IV) and chromium(V) metabolites in the chromium(VI)-glutathione reaction: NMR, ESR, HPLC, and kinetic characterization

1992 • 90 citations

Iron-mediated induction of sister-chromatid exchanges by hydrogen peroxide and superoxide anion

1987 • 75 citations

o-Phenanthroline protects mammalian cells from hydrogen peroxide-induced gene mutation and morphological transformation

1989 • 74 citations

Oxygen-derived free-radical and active oxygen complex formation from cobalt(II) chelates in vitro

1992 • 74 citations

Chromium (IV)-mediated fenton-like reaction causes DNA damage: implication to genotoxicity of chromate.

1996 • 66 citations

Low-Frequency EPR Detection of Chromium(V) Formation by Chromium(VI) Reduction in Whole Live Mice

1994 • 54 citations

DNA damage induced by phorbol ester-stimulated neutrophils is augmented by extracellular cofactors. Role of histidine and metals.

1990 • 51 citations

Chromium(VI) reduction by ascorbate: role of reactive intermediates in DNA damage in vitro.

1994 • 49 citations

Oxygen Transport to Tissue XVI

1994 • 44 citations

Chromium carcinogenicity; A review of experimental animal data

1988 • 34 citations

Spectrophotometric and ESR evidence for vanadium(IV) deferoxamine complexes

1991 • 28 citations

The formation of DNA cleaving species during the reduction of chromate by ascorbate

1994 • 26 citations

Influence of o-Phenanthroline on DNA Single-Strand Breaks, Alkali-Labile Sites, Glutathione Reductase, and Formation of Chromium(V) in Chinese-Hamster V-79 Cells Treated with Sodium Chromate(VI)

1993 • 23 citations