Suppression of experimental autoimmune encephalomyelitis by restraint stress: Sex differences

Physiological Functions of Glucocorticoids in Stress and Their Relation to Pharmacological Actions*

1984 • 3,073 citations

Stress Hormones: Their Interaction and Regulation

1984 • 1,534 citations

Immunoregulatory Feedback Between Interleukin-1 and Glucocorticoid Hormones

1986 • 1,521 citations

Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis.

1981 • 1,281 citations

T‐lymphocyte entry into the central nervous system

1991 • 1,168 citations

Corticosteroids and Lymphoid Cells

1972 • 1,030 citations

The T Lymphocyte in Experimental Allergic Encephalomyelitis

1990 • 1,005 citations

Large Scale Preparation of Myelin Basic Protein from Central Nervous Tissue of Several Mammalian Species

1972 • 949 citations

A molecular basis for bidirectional communication between the immune and neuroendocrine systems.

1989 • 842 citations

Sex hormones, immune responses, and autoimmune diseases. Mechanisms of sex hormone action.

1985 • 816 citations

Inflammatory mediator-induced hypothalamic-pituitary-adrenal axis activation is defective in streptococcal cell wall arthritis-susceptible Lewis rats.

1989 • 723 citations

The Immune-Hypothalamic-Pituitary-Adrenal Axis*

1989 • 671 citations

Corticosteroids inhibit murine macrophage Ia expression and interleukin 1 production.

1982 • 665 citations

Effects of gender and sex steroids on the immune response

1990 • 592 citations

A central nervous system defect in biosynthesis of corticotropin-releasing hormone is associated with susceptibility to streptococcal cell wall-induced arthritis in Lewis rats.

1989 • 579 citations

Specific stimulation of human T lymphocytes by substance P.

1983 • 461 citations

Oral tolerance in experimental autoimmune encephalomyelitis. III. Evidence for clonal anergy.

1991 • 450 citations

Biology of disease. Analysis of autoimmune demyelination: its impact upon multiple sclerosis.

1984 • 424 citations

Stress-related immune suppression: Health implications

1987 • 389 citations

Restraint stress in biomedical research: A review

1986 • 372 citations

Suppression of Immunity by Stress: Effect of a Graded Series of Stressors on Lymphocyte Stimulation in the Rat

1981 • 354 citations

Possible underlying mechanisms of sexual dimorphism in the immune response, fact and hypothesis

1989 • 346 citations

Changes in Blood Hormone Levels during the Immune Response

1975 • 342 citations

Experimental Allergic Encephalomyelitis. A Useful Model for Multiple Sclerosis

1984 • 340 citations

Spontaneous recovery of rats from experimental allergic encephalomyelitis is dependent on regulation of the immune system by endogenous adrenal corticosteroids.

1989 • 339 citations

Plasma corticosterone levels during repeated presentation of two intensities of restraint stress: Chronic stress and habituation

1988 • 295 citations

Noradrenergic sympathetic innervation of the spleen: I. Nerve fibers associate with lymphocytes and macrophages in specific compartments of the splenic white pulp

1987 • 282 citations

Genetic variation in the stress response: susceptibility to experimental allergic encephalomyelitis and implications for human inflammatory disease

1991 • 254 citations

Methods for quantifying the transport of drugs across brain barrier systems

1981 • 214 citations

Innervation of Lymphoid Tissue

1991 • 208 citations

The role of the neuroendocrine system in determining genetic susceptibility to experimental allergic encephalomyelitis in the rat.

1990 • 201 citations

Effect of stressor intensity on habituation of the adrenocortical stress response

1988 • 187 citations

Response of anterior pituitary hormones to chronic stress. The specificity of adaptation

1986 • 155 citations

Effects of chronic stress on plasma corticosterone, ACTH and prolactin

1987 • 154 citations

Blood-brain and blood-spinal cord barrier permeability during the course of experimental allergic encephalomyelitis in the rat

1984 • 133 citations

Chemical sympathectomy augments the severity of experimental allergic encephalomyelitis☆

1988 • 120 citations

Blood-Brain Barrier: Endogenous Modulation by Adrenal-Cortical Function

1985 • 117 citations

Hormonal coordination of the immune response

1982 • 116 citations

Stress and Immune Responses III. Effect of Restraint Stress on Delayed Type Hypersensitivity (DTH) Response, Natural Killer (NK) Activity and Phagocytosis in Mice

1986 • 114 citations

THE MAJOR SITE OF GUINEA‐PIG MYELIN BASIC PROTEIN ENCEPHALITOGENIC IN LEWIS RATS¹²

1977 • 112 citations

Sex and strain differences in the circadian rhythm fluctuation of endocrine and immune function in the rat: implications for rodent models of autoimmune disease

1991 • 108 citations

Immunopharmacology and the regulation of leukocyte function

1983 • 105 citations

Immunological Diseases

1989 • 91 citations

Suppression of Experimental Allergic Encephalomyelitis by Stress.

1962 • 88 citations

Studies on the Species-Variability of Experimental Allergic Encephalomyelitis in Guinea Pigs and Rats

1974 • 87 citations

Selection of Experimental Conditions for the Accurate Determination of Blood — Brain Transfer Constants from Single-Time Experiments: A Theoretical Analysis

1983 • 87 citations

Antigen-specific inhibition of immune interferon production by suppressor cells of autoimmune encephalomyelitis.

1988 • 83 citations

Blood‐brain barrier permeability and immobilization stress

1982 • 79 citations

Changes in the effectiveness of the blood-brain and blood-spinal cord barriers in experimental allergic encephalomyelitis

1981 • 75 citations

Sex Hormones and Immune Function

1991 • 69 citations

A Study of Abnormal Blood-Brain Permeability in Experimental Allergic Encephalomyelitis

1956 • 69 citations

Changes in lymphocyte β-adrenergic receptor density and noradrenaline content of the spleen are early indicators of immune reactivity in acute experimental allergic encephalomyelitis in the Lewis rat

1989 • 68 citations

Brain Vascular Permeability to I¹²⁵Gamma Globulin and Leukocytes in Allergic Encephalomyelitis^*†

1967 • 66 citations

Psychoneuroimmunology

1991 • 65 citations

Stress‐Induced Alteration of Immune Function

1992 • 65 citations

Stress, immunity, and aging

1986 • 62 citations

Effects of Experimental Allergic Encephalomyelitis on Thymus and Adrenal: Relation to Remission and Relapse

1980 • 57 citations

Restraint stress-induced suppression of major histocompatibility complex class II expression by murine peritoneal macrophages

1990 • 51 citations

Transport of sodium from blood to brain in ischemic brain edema.

1987 • 49 citations

A Spatial Analysis of the Blood—Brain Barrier Damage in Experimental Allergic Encephalomyelitis

1985 • 46 citations

Nonspecific stress prevents relapses of experimental allergic encephalomyelitis in rats

1987 • 46 citations

Role of the clotting system in the pathogenesis of neuroimmunologic disease.

1987 • 46 citations

Hypothesis: Antigen-specific T cells prime central nervous system endothelium for recruitment of nonspecific inflammatory cells to effect autoimmune demyelination

1991 • 44 citations

Suppression of the hyperacute form of experimental allergic encephalomyelitis by drugs.

1977 • 34 citations

THE EFFECT OF 'TRAINING' ON THE RELEASE OF CORTICOTROPHIN IN RESPONSE TO MINOR STRESSFUL PROCEDURES IN THE RAT

1970 • 33 citations

Sex difference in Lewis rats in the incidence of recurrent experimental allergic encephalomyelitis

1978 • 33 citations

Protection against experimental encephalomyelitis: Idiotypic autoregulation induced by a non-encephalitogenic T cell clone expressing a cross-reactive T cell receptor V gene

1992 • 31 citations

Antagonistic effects of gamma interferon and steroids on tissue antigenicity.

1986 • 30 citations

Chemotherapy of experimental allergic encephalomyelitis (EAE).

1969 • 29 citations

Limiting-dilution analysis of the frequency of myelin basic protein-reactive T cells in Lewis, PVG/c and BN rats. Implication for susceptibility to autoimmune encephalomyelitis.

1990 • 28 citations

Protection against experimental encephalomyelitis. Idiotypic autoregulation induced by a nonencephalitogenic T cell clone expressing a cross-reactive T cell receptor V gene.

1991 • 27 citations

Effects on immune responses by chronic stress are modulated by aging

1987 • 27 citations

Experimental allergic encephalomyelitis and corticosterone studies in resistant and susceptible rat strains

1991 • 25 citations

Enhancement of Experimental Allergic Encephalomyelitis by Adrenalectomy.

1962 • 25 citations

The Role of the Adrenal in Relapses of Experimental Allergic Encephalomyelitis

1975 • 25 citations

Allergic encephalomyelitis: Inhibition of cellular passive transfer by exogenous and endogenous steroids

1969 • 23 citations

Immunoregulatory processes in experimental allergic encephalomyelitis and multiple sclerosis

1985 • 22 citations

Splenic noradrenergic and adrenocortical responses during the preclinical and clinical stages of adoptively transfered experimental autoimmune encephalomyelitis (EAE)

1990 • 20 citations

Impairment of immune function after cessation of long-term chronic stress

1986 • 19 citations

Chemical prevention of experimental allergic encephalomyelitis in rats: a quantitative evaluation of steroids and various non-steroid drugs.

1971 • 17 citations

Gangliosides suppress the proliferation of autoreactive cells in experimental allergic encephalomyelitis: Ganglioside effects on IL-2 activity

1987 • 16 citations

Corticosteroids and the radiation effect in regenerating liver of the rat

1959 • 11 citations

Development of experimental allergic encephalomyelitis during steroid administration. Outcome of neurological immune-mediated disorders under immunosuppressive therapy.

1991 • 8 citations