Ultrastructural Organic-Inorganic Relationships in Calcified Tissues: Cartilage and Bone vs. Enamel

Fine structure of early cartilage calcification

1967 • 678 citations

An electron microscopic study of initial intramembranous osteogenesis

1969 • 303 citations

The Locus of Initial Calcification in Cartilage and Bone

1971 • 269 citations

THE STRUCTURE AND ORGANIZATION OF, AND THE RELATIONSHIP BETWEEN THE ORGANIC MATRIX AND THE INORGANIC CRYSTALS OF EMBRYONIC BOVINE ENAMEL

1964 • 186 citations

Electron diffraction and electron probe microanalysis of the mineral phase of bone tissue prepared by anhydrous techniques

1978 • 184 citations

Cartilage macromolecules and the calcification of cartilage matrix

1989 • 176 citations

Biochemical and immunohistochemical evidence that in cartilage an alkaline phosphatase is a Ca2+-binding glycoprotein.

1986 • 158 citations

Localization of bone sialoprotein (BSP) to Golgi and post-Golgi secretory structures in osteoblasts and to discrete sites in early bone matrix.

1993 • 143 citations

Mineralization and metabolic response in serially passaged adult rat bone cells

1980 • 126 citations

THE PROBLEM OF DEMINERALISATION IN THIN SECTIONS OF FULLY CALCIFIED BONE

1964 • 122 citations

Further investigation on the organic/inorganic relationships in calcifying cartilage

1969 • 98 citations

Organization of crystals in enamel

1989 • 93 citations

Role of lipids in calcification of cartilage

1989 • 91 citations

Chemical modifications in osteones during calcification

1970 • 84 citations

THE ORGANIC-INORGANIC RELATIONSHIP IN CALCIFIED MITOCHONDRIA

1973 • 84 citations

Quantitative spatial distributions of calcium, phosphorus, and sulfur in calcifying epiphysis by high resolution electron spectroscopic imaging.

1983 • 82 citations

Developmental appearance and ultrastructural immunolocalization of a major 66 kDa phosphoprotein in embryonic and post‐natal chicken bone

1990 • 80 citations

Histochemical and electron microscope investigations on medullary bone

1975 • 75 citations

The fine structure of decalcified cartilage and bone: A comparison between decalcification procedures performed before and after embedding

1978 • 63 citations

Extracellular alkaline phosphatase activity in mineralizing matrices of cartilage and bone: ultrastructural localization using a cerium-based method

1992 • 60 citations

III. The structure of the organic stroma of human enamel during amelogenesis

1962 • 60 citations

Glycoconjugates in Dentinogenesis and Dentine

1987 • 53 citations

A Previously Unrecognized Material in Mammalian Spermatozoa as Revealed by Malachite Green and Pyronine

1972 • 52 citations

An ultrastructural study of the role of calcification nodules in the mineralization of woven bone

1979 • 50 citations

Matrix-Mineral Relationships-A. Morphologist's Viewpoint

1979 • 50 citations

Cartilage calcification: an ultrastructural, histochemical, and analytical x-ray microprobe study of the zone of calcification in the normal avian epiphyseal growth plate.

1982 • 46 citations

Acridine orange stabilization of glycosaminoglycans in beginning endochondral ossification

1981 • 46 citations

The solid, calcium-phosphate mineral phases in embryonic chick bone characterized by high-voltage electron diffraction

1986 • 44 citations

Morphological studies on the distribution of enamel matrix proteins using routine electron microscopy and freeze‐fracture replicas in the rat incisor

1985 • 40 citations

Electron microscopic studies on the potential loss of crystallites from routinely processed sections of young enamel in the rat incisor

1982 • 39 citations

The structural basis of calcification

1984 • 39 citations

Organic-inorganic relationships, and immunohistochemical localization of amelogenins and enamelins in developing enamel.

1986 • 37 citations

An electron microscopic histochemical and analytical X-ray microprobe study of calcification in Bruch's membrane from human eyes.

1981 • 34 citations

The Ultrastructure of the Organic Phase Associated with the Inorganic Substance in Calcified Tissues

1988 • 32 citations

Monoclonal antibody and immunogold cytochemical localization of amelogenins in bovine secretory amelogenesis

1987 • 30 citations

The effect of osmium postfixation and uranyl and lead staining on the ultrastrucure of young enamel in the rat incisor

1983 • 29 citations

Influence of calcium depletion on medullary bone of laying hens

1980 • 28 citations

Earliest enamel deposits of the rat incisor examined by electron microscopy, electron diffraction, and electron probe microanalysis

1988 • 27 citations

Visualization of glycosaminoglycans in rat incisor predentin and dentin with cetylpyridinium chloride-glutaraldehyde as fixative.

1990 • 26 citations

Ultrastructural observations on the inorganic/organic rellationships in early cartilage calcification

1971 • 26 citations

Localization of malachite green positive lipids in the matrix of bone nodule formed in vitro

1992 • 22 citations

Ultrastructural cytochemistry of cartilage proteoglycans and their relation to the calcification process

1990 • 22 citations

A further contribution on the ultrastructure of calcifying cartilage

1971 • 22 citations

An electron microscopic examination for the presence of acid groups in the organic matrix of mineralization nodules in foetal bone

1982 • 20 citations

Crystal-associated matrix components in rat incisor enamel

1986 • 19 citations

THE RELATIONSHIP BETWEEN THE APATITE CRYSTALS AND THE ORGANIC MATRIX OF RAT ENAMEL

1962 • 17 citations

Ultrastructural characterization of extracellular matrix vesicles in the mineralizing fronts of apical cementum in cats

1985 • 17 citations

Immunohistochemical investigation on the presence of chondroitin sulfate in calcification nodules of epiphyseal cartilage.

1992 • 13 citations

Morphological investigation of epiphyseal cartilage after glutaraldehyde-malachite green fixation

1994 • 12 citations

Immunocytochemical localization of enamelin proteins in developing bovine teeth

1990 • 10 citations

An improved periodic acid-thiosemicarbazide-osmium technique to reveal glycoconjugates at the molecular level in situ.

1986 • 9 citations

Ultrastructural Demonstration of the Carbohydrate in Developing Mantle Dentine with Soybean Agglutinin-Gold Complexes

1988 • 7 citations

The use of chromic potassium sulphate in bone electron microscopy.

1984 • 4 citations