Ultrastructural cytochemistry of cartilage proteoglycans and their relation to the calcification process

Cell Biology of Extracellular Matrix

1988 • 1,498 citations

Ultrastructure of the Connective Tissue Matrix

1984 • 260 citations

Connective tissue diseases

2020 • 242 citations

Cartilage ultrastructure after high pressure freezing, freeze substitution, and low temperature embedding. I. Chondrocyte ultrastructure--implications for the theories of mineralization and vascular invasion.

1984 • 225 citations

An immunoelectron microscope study of the organization of proteoglycan monomer, link protein, and collagen in the matrix of articular cartilage.

1982 • 223 citations

Improved cartilage fixation by ruthenium hexammine trichloride (RHT)

1982 • 195 citations

STUDIES ON ULTRASTRUCTURAL IDENTIFICATION AND DISTRIBUTION OF PROTEIN-POLYSACCHARIDE IN CARTILAGE MATRIX

1967 • 195 citations

Electron microscopic demonstration of proteoglycans in guinea pig epiphyseal cartilage

1973 • 189 citations

Biology of Proteoglycans

1987 • 182 citations

Structure and Function of the Growth Plate

1978 • 164 citations

Role of proteoglycans in endochondral ossification: immunofluorescent localization of link protein and proteoglycan monomer in bovine fetal epiphyseal growth plate.

1982 • 159 citations

The use of osmium-thiocarbohydrazide-osmium (OTO) and ferrocyanide-reduced osmium methods to enhance membrane contrast and preservation in cultured cells.

1984 • 158 citations

Proteoglycans

1981 • 151 citations

Cartilage proteoglycans: comparison of sectioned and spread whole molecules

1980 • 150 citations

Cartilage ultrastructure after high pressure freezing, freeze substitution, and low temperature embedding. II. Intercellular matrix ultrastructure - preservation of proteoglycans in their native state.

1984 • 138 citations

THE FINE STRUCTURE OF BOVINE NASAL CARTILAGE

1971 • 138 citations

Localization of a dermatan sulfate proteoglycan (DS-PGII) in cartilage and the presence of an immunologically related species in other tissues.

1986 • 131 citations

Proteoglycan Structure in Calcifying Cartilage

1983 • 123 citations

Crystallization and some properties of chondroitinase from Arthrobacter aurescens.

1975 • 117 citations

Simultaneous localization of proteoglycan by light and electron microscopy using toluidine blue O. A study of epiphyseal cartilage.

1976 • 116 citations

Proteoglycans of mineralizing rib and epiphyseal cartilage

1975 • 116 citations

EVIDENCE FOR CHANGES IN PROTEIN POLYSACCHARIDE ASSOCIATED WITH THE ONSET OF CALCIFICATION IN CARTILAGE

1968 • 116 citations

A comparative study between a chondroitinase B and a chondroitinase AC from Flavobacterium heparinum: Isolation of a chondroitinase AC-susceptible dodecasaccharide from chondroitin sulphate B

1975 • 115 citations

The localization of proteoglycan by light and electron microscopy using Safranin O

1976 • 112 citations

Further investigation on the organic/inorganic relationships in calcifying cartilage

1969 • 98 citations

The disposition of proteinpoly-saccharide in the epiphysial plate cartilage of the young rabbit

1970 • 89 citations

Quantitative spatial distributions of calcium, phosphorus, and sulfur in calcifying epiphysis by high resolution electron spectroscopic imaging.

1983 • 82 citations

Alcian Blue staining of cartilage for electron microscopy. Application of the critical electrolyte concentration principle

1975 • 72 citations

Collagen-proteoglycan interaction

1984 • 70 citations

Electron microscopic visualization of proteoglycans with Alcian Blue

1975 • 69 citations

Preparation and circular dichroism analysis of sodium hyaluronate oligosaccharides and chondroitin

1981 • 66 citations

The fine structure of decalcified cartilage and bone: A comparison between decalcification procedures performed before and after embedding

1978 • 63 citations

Ultrastructural modifications of proteoglycans coincident with mineralization in local regions of rat growth plate.

1985 • 61 citations

An electron microscopic and spectroscopic study of murine epiphyseal cartilage: Analysis of fine structure and matrix vesicles preserved by slam freezing and freeze substitution

1988 • 59 citations

Organization of extracellular matrix in epiphyseal growth plate.

1971 • 59 citations

29 Protein???polysaccharides of Cartilage and Bone in Health and Disease

1970 • 58 citations

LANTHANUM STAINING OF DEVELOPING CHICK CARTILAGE AND REAGGREGATING CARTILAGE CELLS

1970 • 51 citations

In situ localization of cartilage extracellular matrix components by immunoelectron microscopy after cryotechnical tissue processing.

1987 • 49 citations

Cartilage calcification: an ultrastructural, histochemical, and analytical x-ray microprobe study of the zone of calcification in the normal avian epiphyseal growth plate.

1982 • 46 citations

Ultrastructure of Growing Epiphyseal Cartilage Processed by Rapid Freezing and Freeze-Substitution

1983 • 45 citations

Interaction of sulfated glycosaminoglycans with lectins.

1981 • 44 citations

The measurement of proteoglycan in the mineralizing region of the rat growth plate.

1982 • 40 citations

Cytochemistry of complex carbohydrates by light and electron microscopy: available methods and their application.

1983 • 39 citations

The amount of proteoglycans in cartilage matrix and the onset of mineralization

1984 • 36 citations

Light and electron microscope analysis of lectin binding to adult rat liver in situ.

1984 • 36 citations

Patterns of proteoglycan degradation by a neutral protease from human growth-plate epiphyseal cartilage.

1982 • 35 citations

Proteoglycans from bovine nasal and articular cartilages. Fractionation of the link proteins by wheat germ agglutinin affinity chromatography.

1985 • 35 citations

Patterns of proteoglycan degradation by a neutral protease from human growth-plate epiphyseal cartilage.

1982 • 33 citations

Ultrastructural cytochemistry and immunocytochemistry of sulfated glycosaminoglycans in epiphyseal cartilage.

1982 • 32 citations

Ultrastructural localization of acidic glycoconjugates with the low iron diamine method.

1982 • 31 citations

[124] Chondroitinases from Proteus vulgaris and Flavobacterium heparinum

1972 • 28 citations

Electron microscopic analysis of articular cartilage proteoglycan degradation by growth plate enzymes

1987 • 28 citations

Ultrastructural cytochemistry and immunocytochemistry of proteoglycans associated with epiphyseal cartilage calcification.

1983 • 27 citations

Ultrastructural observations on the inorganic/organic rellationships in early cartilage calcification

1971 • 26 citations

Alterations in the composition of growth cartilage septa during calcification studied by microscopic X-ray elemental analysis

1968 • 26 citations

Electron-microscopic microprobe analysis on the initial stages of mineral formation in the epiphyseal growth plate

1981 • 25 citations

Concanavalin A-binding link protein in the proteoglycan aggregate of hyaline cartilage

1982 • 19 citations

Ultrastructural visualization of complex carbohydrates in epiphyseal cartilage with the tannic acid-metal salt methods.

1983 • 18 citations

In Vivo Degradation Systems of the Epiphyseal Cartilage

1986 • 13 citations

Specific binding of peanut agglutinin and soybean agglutinin to chondroitinase ABC-digested cartilage proteoglycans: Histochemical, ultrastructural cytochemical, and biochemical characterization

1988 • 12 citations

Isolation, characterization and immunohistochemical localization of a dermatan sulfate-containing proteoglycan from bovine fetal epiphyseal cartilage.

1982 • 10 citations

Localization of antigenic components in proteoglycan aggregate of bovine nasal cartilage

1983 • 10 citations

Electron microscopical demonstration of sulphated mucopolysaccharides in mouse tracheal cartilage with a diaminobenzidine-osmium tetroxide technique

1972 • 9 citations

Untitled

1984 • 3 citations

Contributions of light and electron histochemical techniques to the study of proteoglycan function in cartilage.

1984 • 2 citations