The significance of serum levels of insulin‐like growth factor‐1 in patients with prostate cancer

Insulin-like Growth Factor (IGF)-binding Protein-3 Induces Apoptosis and Mediates the Effects of Transforming Growth Factor-β1 on Programmed Cell Death through a p53- and IGF-independent Mechanism

1997 • 725 citations

Insulin-Like Growth Factor 1 and Prostate Cancer Risk: A Population-Based, Case-Control Study

1998 • 592 citations

Insulin-like growth factor 1 in relation to prostate cancer and benign prostatic hyperplasia

1997 • 376 citations

Insulin-Like Growth Factors (IGFs), IGF Receptors, and IGF-Binding Proteins in Primary Cultures of Prostate Epithelial Cells*

1991 • 361 citations

Antisense RNA to the type I insulin-like growth factor receptor suppresses tumor growth and prevents invasion by rat prostate cancer cells in vivo.

1996 • 239 citations

Insulin‐like growth factor I: Action and receptor characterization in human prostate cancer cell lines

1993 • 215 citations

Elevated levels of insulin-like growth factor-binding protein-2 in the serum of prostate cancer patients.

1993 • 201 citations

Autocrine regulation of cell proliferation by the insulin-like growth factor (IGF) and IGF binding protein-3 protease system in a human prostate carcinoma cell line (PC-3).

1995 • 164 citations

Protein and messenger ribonucleic acid (mRNA) for the type 1 insulin-like growth factor (IGF) receptor is decreased and IGF-II mRNA is increased in human prostate carcinoma compared to benign prostate epithelium.

1996 • 162 citations

The IGF Axis in the Prostate

1994 • 148 citations

Sex hormone-induced prostatic carcinogenesis in the Noble rat: The role of insulin-like growth factor-1 (IGF-1) and vascular endothelial growth factor (VEGF) in the development of prostate cancer

1998 • 123 citations

Elevated levels of insulin-like growth factor-binding protein-2 in the serum of prostate cancer patients

1993 • 100 citations

The Effects of Growth Factors Associated with Osteoblasts on Prostate Carcinoma Proliferation and Chemotaxis: Implications for the Development of Metastatic Disease*

1997 • 95 citations

Discordance of assay methods creates pitfalls for the interpretation of prostate-specific antigen values

1996 • 94 citations

Protein and messenger ribonucleic acid (mRNA) for the type 1 insulin- like growth factor (IGF) receptor is decreased and IGF-II mRNA is increased in human prostate carcinoma compared to benign prostate epithelium

1996 • 90 citations

DIFFERENTIAL EXPRESSION OF INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS IN HIGH VERSUS LOW GLEASON SCORE PROSTATE CANCER

1998 • 76 citations

The Effects of Growth Factors Associated with Osteoblasts on Prostate Carcinoma Proliferation and Chemotaxis: Implications for the Development of Metastatic Disease

1997 • 36 citations

Serum insulin-like growth factor-I (IGF-I) and IGF binding protein-3 levels in children with precocious puberty treated with gonadotropin-releasing hormone analog without or in combination with cyproterone acetate

1997 • 10 citations

Prostate-cancer link sours IGF-1

1998 • 4 citations

[Insulin growth factor I (IGF-I) in normal, hyperplastic, and tumor prostatic tissue].

1996 • 2 citations

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