A sodium channel defect in hyperkalemic periodic paralysis: Potassium-induced failure of inactivation

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

1989 • 7,327 citations

Structural parts involved in activation and inactivation of the sodium channel

1989 • 1,189 citations

Sodium and calcium channels in bovine chromaffin cells

1982 • 983 citations

Correction of the cystic fibrosis defect in vitro by retrovirus-mediated gene transfer

1990 • 576 citations

Primary structure and functional expression of a mammalian skeletal muscle sodium channel

1989 • 561 citations

Destruction of Sodium Conductance Inactivation in Squid Axons Perfused with Pronase

1973 • 540 citations

Ryanodine receptor gene is a candidate for predisposition to malignant hyperthermia

1990 • 508 citations

Two types of calcium channels in the somatic membrane of new‐born rat dorsal root ganglion neurones.

1985 • 412 citations

Chloride and potassium channels in cystic fibrosis airway epithelia

1986 • 392 citations

Identification of an Intracellular Peptide Segment Involved in Sodium Channel Inactivation

1988 • 382 citations

A voltage-dependent persistent sodium current in mammalian hippocampal neurons.

1990 • 377 citations

A rat brain na+ channel α subunit with novel gating properties

1988 • 359 citations

Phosphorylation fails to activate chloride channels from cystic fibrosis airway cells

1987 • 341 citations

Hyperkalemic Periodic Paralysis and the Adult Muscle Sodium Channel α-Subunit Gene

1990 • 304 citations

Adynamia episodica hereditaria with myotonia: A non‐inactivating sodium current and the effect of extracellular pH

1987 • 234 citations

Effect of N-bromoacetamide on single sodium channel currents in excised membrane patches.

1982 • 216 citations

Abnormal ryanodine receptor channels in malignant hyperthermia

1990 • 208 citations

Two modes of gating during late Na+ channel currents in frog sartorius muscle.

1986 • 182 citations

Voltage-dependent gating of single sodium channels from mammalian neuroblastoma cells

1987 • 167 citations

Fast and slow gating of sodium channels encoded by a single mRNA

1990 • 162 citations

Functional Differences Between Two Classes of Sodium Channels in Developing Rat Skeletal Muscle

1986 • 161 citations

Removal of sodium channel inactivation in squid giant axons by n-bromoacetamide.

1978 • 149 citations

Open channel noise. I. Noise in acetylcholine receptor currents suggests conformational fluctuations

1985 • 147 citations

Muscle membrane potentials in episodic adynamia

1963 • 141 citations

Adynamia Episodica Hereditaria

1956 • 129 citations

Adynamia episodica hereditaria

1957 • 123 citations

Slow inactivation of currents in cardiac Purkinje fibres

1968 • 115 citations

Modification of Na channel gating by an alpha scorpion toxin from Tityus serrulatus.

1989 • 113 citations

Functional Properties of Rat Brain Sodium Channels Expressed in a Somatic Cell Line

1990 • 104 citations

Mechanism of action of a polypeptide neurotoxin from the coral Goniopora on sodium channels in mouse neuroblastoma cells.

1986 • 104 citations

Two cases of adynamia episodica hereditaria: In vitro investigation of muscle cell membrane and contraction parameters

1983 • 97 citations

Voltage clamp analysis of tetrodotoxin-sensitive and -insensitive sodium channels in rat muscle cells developing in vitro

1985 • 94 citations

Characteristics of Na+ channels and Cl‐ conductance in resealed muscle fibre segments from patients with myotonic dystrophy.

1990 • 92 citations

Kinetic properties of single sodium channels in rat heart and rat brain.

1989 • 90 citations

Expression of the Duchenne's muscular dystrophy gene in cultured muscle cells.

1987 • 88 citations

Schwartz–Jampel syndrome: II. Na⁺ channel defect causes myotonia

1990 • 57 citations

Abnormalities of the fast sodium current in myotonic dystrophy, recessive generalized myotonia, and adynamia episodica

1989 • 50 citations

Kinetic diversity of Na+ channel bursts in frog skeletal muscle.

1989 • 33 citations

The primary periodic paralyses

1985 • 27 citations

Incomplete inactivation of sodium currents in nonperfused squid axon

1980 • 26 citations

Mechanism of Action of a Polypeptide Neurotoxin from the Coral Goniopora on Sodium Channels in Mouse Neuroblastoma Cells

1986 • 12 citations