A₂‐purinoceptor‐mediated relaxation in the guinea‐pig coronary vasculature: a role for nitric oxide

Nitric oxide: physiology, pathophysiology, and pharmacology.

1991 • 15,563 citations

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1980 • 12,033 citations

Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs

1971 • 8,596 citations

Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo

1990 • 1,869 citations

Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin.

1978 • 1,559 citations

The physiological activity of adenine compounds with especial reference to their action upon the mammalian heart1

1929 • 1,470 citations

L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation

1988 • 1,379 citations

Cardiac nucleotides in hypoxia: possible role in regulation of coronary blood flow

1963 • 1,015 citations

Arterial walls are protected against deposition of platelet thrombi by a substance (prostaglandin X) which they make from prostaglandin endoperoxides

1976 • 1,012 citations

The role of adenosine in the regulation of coronary blood flow.

1980 • 877 citations

A basis for distinguishing two types of purinergic receptor

1978 • 725 citations

A novel citrulline-forming enzyme implicated in the formation of nitric oxide by vascular endothelial cells

1989 • 612 citations

Arginine is a physiological precursor of endothelium-derived nitric oxide

1988 • 392 citations

8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) ? a selective high affinity antagonist radioligand for A1 adenosine receptors

1987 • 390 citations

Purine Receptors in Mammalian Tissues: Pharmacology and Functional Significance

1987 • 302 citations

Biosynthesis of endothelium-derived relaxing factor: A cytosolic enzyme in porcine aortic endothelial cells Ca2+-dependently converts L-arginine into an activator of soluble guanylyl cyclase

1989 • 271 citations

CGS 21680C, an A2 selective adenosine receptor agonist with preferential hypotensive activity.

1989 • 245 citations

The coronary endothelium: a highly active metabolic barrier for adenosine

1985 • 207 citations

Adenosine relaxes the aorta by interacting with an A2 receptor and an intracellular site

1983 • 132 citations

Contribution of coronary endothelial cells to cardiac adenosine production

1986 • 127 citations

L-arginine availability determines the duration of acetylcholine-induced systemic vasodilatation in vivo

1989 • 126 citations

Adenosine Receptors

1990 • 104 citations

N6-Cycloalkyladenosines. Potent, A1-selective adenosine agonists

1985 • 98 citations

PD 116,948, a highly selective A1 adenosine receptor antagonist

1987 • 90 citations

Relaxant effects of ATP and adenosine on canine large and small coronary arteries in vitro

1987 • 55 citations

Role of nitric oxide synthesis in the regulation of coronary vascular tone in the isolated perfused rabbit heart

1992 • 51 citations

Purinergic relaxation and hyperpolarization in guinea pig and rabbit coronary artery: role of the endothelium.

1992 • 49 citations

Apparent affinity of 1,3‐dipropyl‐8‐cyclopentylxanthine for adenosine A₁ and A₂ receptors in isolated tissues from guinea‐pigs

1989 • 46 citations

Functional evidence for the presence of adenosine A2-receptors in cultured coronary endothelial cells

1987 • 44 citations

Apparent affinity of some 8‐phenyl‐substituted xanthines at adenosine receptors in guinea‐pig aorta and atria

1987 • 39 citations

Functional role of intravascular coronary endothelial adenosine receptors

1992 • 30 citations

Effects of nitric oxide synthase inhibitors, <scp>l</scp>‐N^G‐nitroarginine and <scp>l</scp>‐N^G‐nitroarginine methyl ester, on responses to vasodilators of the guinea‐pig coronary vasculature

1992 • 25 citations

AN INVESTIGATION OF THE RECEPTORS INVOLVED IN THE CORONARY VASODILATORY EFFECT OF ADENOSINE ANALOGUES

1985 • 19 citations

Adenosine Receptor Sub-types in Isolated Tissues: Antagonist Studies

1990 • 13 citations

Structure Activity Relationships for Adenosine Antagonists

1990 • 13 citations

Effect of adenosine on the formation of prostacyclin in the rabbit isolated heart

1988 • 13 citations

Prostanoids Contribute to Endothelium-Dependent Coronary Vasodilation in Guinea Pigs

1990 • 12 citations

Are there two Types of Adenosine Receptors in Peripheral Tissues?

1985 • 12 citations

Adenosine Agonists and Antagonists

1990 • 10 citations

Purinoceptor Subtypes in the Coronary-artery

1990 • 2 citations