Transcriptional Repression by the Promyelocytic Leukemia Protein, PML

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

A human retinoic acid receptor which belongs to the family of nuclear receptors

1987 • 2,245 citations

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

1995 • 2,059 citations

A transcriptional co-repressor that interacts with nuclear hormone receptors

1995 • 1,744 citations

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

1991 • 1,463 citations

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

1991 • 1,371 citations

Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor

1978 • 1,284 citations

The V(D)J recombination activating gene, RAG-1

1989 • 1,164 citations

Identification of a retinoic acid responsive element in the retinoic acid receptor & beta;gene

1990 • 1,018 citations

Deletion analysis of GAL4 defines two transcriptional activating segments

1987 • 898 citations

Cloning of murine α and β retinoic acid receptors and a novel receptor γ predominantly expressed in skin

1989 • 804 citations

A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein

1994 • 798 citations

A versatilein vivoandin vitroeukaryotic expression vector for protein engineering

1988 • 686 citations

A model fungal gene regulatory mechanism: the GAL genes of Saccharomyces cerevisiae

1987 • 676 citations

Retinoic acid regulates aberrant nuclear localization of PML-RARα in acute promyelocytic leukemia cells

1994 • 668 citations

The retinoid receptors.

1994 • 665 citations

The acute promyelocytic leukemia-specific PML-RARα fusion protein inhibits differentiation and promotes survival of myeloid precursor cells

1993 • 602 citations

Polarity-specific activities of retinoic acid receptors determined by a co-repressor

1995 • 569 citations

The t(15;17) translocation alters a nuclear body in a retinoic acid-reversible fashion.

1994 • 492 citations

Acute promyelocytic leukemia: from genetics to treatment

1994 • 474 citations

Characterization of a Zinc Finger Gene Disrupted by the t(15;17) in Acute Promyelocytic Leukemia

1991 • 464 citations

Structure, localization and transcriptional properties of two classes of retinoic acid receptor alpha fusion proteins in acute promyelocytic leukemia (APL): structural similarities with a new family of oncoproteins.

1992 • 441 citations

Acute promyelocytic leukemia: from genetics to treatment

1994 • 384 citations

PMLRAR homodimers: distinct DNA binding properties and heteromeric interactions with RXR.

1993 • 307 citations

RARs and RXRs: evidence for two autonomous transactivation functions (AF-1 and AF-2) and heterodimerization in vivo.

1993 • 305 citations

A transferable silencing domain is present in the thyroid hormone receptor, in the v-erbA oncogene product and in the retinoic acid receptor.

1992 • 302 citations

PML, a growth suppressor disrupted in acute promyelocytic leukemia.

1994 • 296 citations

Structure and origin of the acute promyelocytic leukemia myl/RAR alpha cDNA and characterization of its retinoid-binding and transactivation properties.

1991 • 291 citations

Leucine zippers of fos, jun and GCN4 dictate dimerization specificity and thereby control DNA binding

1989 • 281 citations

Transcriptional induction of the PML growth suppressor gene by interferons is mediated through an ISRE and a GAS element.

1995 • 268 citations

A novel zinc finger coiled-coil domain in a family of nuclear proteins

1992 • 260 citations

The PML growth-suppressor has an altered expression in human oncogenesis.

1995 • 241 citations

Characterization of the IE110 Gene of Herpes Simplex Virus Type 1

1986 • 192 citations

A functional interaction between the C-terminal domain of RNA polymerase II and the negative regulator SIN1

1991 • 176 citations

rpt-1, an intracellular protein from helper/inducer T cells that regulates gene expression of interleukin 2 receptor and human immunodeficiency virus type 1.

1988 • 150 citations

Development of a highly efficient expression cDNA cloning system: application to oncogene isolation.

1991 • 145 citations

The PML gene encodes a phosphoprotein associated with the nuclear matrix

1995 • 136 citations

Analysis of the Growth and Transformation Suppressor Domains of Promyelocytic Leukemia Gene, PML

1996 • 129 citations

The C-terminal 79 amino acids of the herpes simplex virus regulatory protein, Vmw65, efficiently activate transcription in yeast and mammalian cells in chimeric DNA-binding proteins.

1989 • 127 citations

Conserved motifs in Fos and Jun define a new class of activation domain.

1992 • 120 citations

The Retinoblastoma Susceptibility Gene Product Represses Transcription When Directly Bound to the Promoter

1995 • 115 citations

The PML-RAR alpha gene product of the t(15;17) translocation inhibits retinoic acid-induced granulocytic differentiation and mediated transactivation in human myeloid cells.

1994 • 107 citations

Site-specific conformational alteration of the Oct-1 POU domain-DNA complex as the basis for differential recognition by Vmw65 (VP16)

1994 • 81 citations

Effect of PML and PML-RAR on the transactivation properties and subcellular distribution of steroid hormone receptors.

1995 • 71 citations

The PML-retinoic acid receptor alpha translocation converts the receptor from an inhibitor to a retinoic acid-dependent activator of transcription factor AP-1.

1993 • 69 citations

Wild type GAL4 binds cooperatively to the GAL1-10 UASG in vitro

1993 • 51 citations

Promyelocytic leukemia-specific PML-retinoic acid alpha receptor fusion protein interferes with erythroid differentiation of human erythroleukemia K562 cells.

1995 • 44 citations

An inhibitor domain in c-Fos regulates activation domains containing the HOB1 motif.

1995 • 42 citations

RET PROTOONCOGENE AND HUMAN-DISEASES - REVIEW

1994 • 7 citations