Ras activation of genes: Mob-1 as a model.

ras oncogenes in human cancer: a review.

1989 • 5,116 citations

Differential Display of Eukaryotic Messenger RNA by Means of the Polymerase Chain Reaction

1992 • 5,105 citations

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1983 • 2,871 citations

G ₁ Events and Regulation of Cell Proliferation

1989 • 2,203 citations

The p53 proto-oncogene can act as a suppressor of transformation

1989 • 2,019 citations

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

1987 • 1,792 citations

Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue

1983 • 1,028 citations

Complexes of Ras⋅GTP with Raf-1 and Mitogen-Activated Protein Kinase Kinase

1993 • 987 citations

γ-Interferon transcriptionally regulates an early-response gene containing homology to platelet proteins

1985 • 949 citations

Distribution and cloning of eukaryotic mRNAs by means of differential display: refinements and optimization

1993 • 874 citations

Cooperation between oncogenes

1991 • 792 citations

Isolation of a transforming sequence from a human bladder carcinoma cell line

1982 • 776 citations

Signaling by the cytokine receptor superfamily: JAKs and STATs

1994 • 659 citations

Biochemical characterization of a gamma interferon-inducible cytokine (IP-10).

1987 • 643 citations

Mutation is required to activate the p53 gene for cooperation with the ras oncogene and transformation

1989 • 599 citations

Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein.

1991 • 544 citations

Aberrant expression of the p53 oncoprotein is a common feature of a wide spectrum of human malignancies.

1991 • 512 citations

Molecular characterization and chromosomal mapping of melanoma growth stimulatory activity, a growth factor structurally related to beta-thromboglobulin.

1988 • 357 citations

Constitutive overexpression of a growth-regulated gene in transformed Chinese hamster and human cells.

1987 • 283 citations

New vectors for high level expression of recombinant proteins in bacteria

1992 • 244 citations

Cooperative interaction between interferon (IFN) stimulus response element and kappa B sequence motifs controls IFN gamma- and lipopolysaccharide-stimulated transcription from the murine IP-10 promoter.

1993 • 242 citations

Effect of a dominant inhibitory Ha-ras mutation on mitogenic signal transduction in NIH 3T3 cells.

1990 • 242 citations

Raf-1 protein kinase activates the NF-kappa B transcription factor by dissociating the cytoplasmic NF-kappa B-I kappa B complex.

1993 • 209 citations

Transformation by Rous sarcoma virus induces a novel gene with homology to a mitogenic platelet protein

1987 • 206 citations

Structural and biological characteristics of connective tissue activating peptide (CTAP-III), a major human platelet-derived growth factor.

1983 • 181 citations

Identification of CRG-2. An interferon-inducible mRNA predicted to encode a murine monokine.

1990 • 172 citations

Induction of NF-kappa B DNA-binding activity during the G0-to-G1 transition in mouse fibroblasts.

1991 • 167 citations

Expression of raf oncogenes activates the PEA1 transcription factor motif.

1989 • 101 citations

Two burgeoning families of platelet factor 4-related proteins: mediators of the inflammatory response.

1990 • 87 citations

Oncogene activation of human keratin 18 transcription via the Ras signal transduction pathway.

1994 • 80 citations

Increased proliferation of human synovial fibroblasts treated with recombinant immune interferon.

1985 • 79 citations

Methods for cloning and analysis of eukaryotic genes

1990 • 71 citations

Effect of a Dominant Inhibitory Ha-ras Mutation on Mitogenic Signal Transduction in NIH 3T3 Cells

1990 • 42 citations

Induction of NF-κB DNA-Binding Activity during the G₀-to-G₁ Transition in Mouse Fibroblasts

1991 • 38 citations

Oncogene activation of HIV-LTR-driven expression via the NF-ϰB binding sites

1993 • 33 citations

Characterization of G1 transit induced by the mitogenic-oncogenic viral Ki-ras gene product.

1986 • 33 citations

Persistence of carcinogen-altered cell population in rat urothelium which can be promoted to tumors by chronic inflammatory stimulus.

1994 • 30 citations

Expression of raf Oncogenes Activates the PEA1 Transcription Factor Motif

1989 • 27 citations